Search results for "regression"
showing 10 items of 2619 documents
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
2021
Abstract Background Biological aging estimators derived from DNA methylation data are heritable and correlate with morbidity and mortality. Consequently, identification of genetic and environmental contributors to the variation in these measures in populations has become a major goal in the field. Results Leveraging DNA methylation and SNP data from more than 40,000 individuals, we identify 137 genome-wide significant loci, of which 113 are novel, from genome-wide association study (GWAS) meta-analyses of four epigenetic clocks and epigenetic surrogate markers for granulocyte proportions and plasminogen activator inhibitor 1 levels, respectively. We find evidence for shared genetic loci ass…
Determination of the modulus of elasticity of bone material by an acoustical approach at the forearm distinguishes women with and without vertebral f…
2002
The modulus of elasticity is a parameter characterizing fracture stability of bone independent of bone mineral density. Measurement of acoustical properties of the forearm by determination of the resonant frequency of the ulna in longitudinal direction as a function of sound transmission velocity after adjustment of the measuring result by ulna length yields information about the modulus of elasticity. It was the aim of this study to investigate whether this parameter may distinguish between subjects with and without vertebral fractures independent of bone mineral density. Fifty females (61.1 +/- 9.1 years) were enrolled into the study, 25 with, and 25 age-matched without prevalent osteopor…
Combined resistance and balance-jumping exercise reduces older women's injurious falls and fractures: 5-year follow-up study
2014
BACKGROUND AND OBJECTIVE: previously, a randomised controlled exercise intervention study (RCT) showed that combined resistance and balance-jumping training (COMB) improved physical functioning and bone strength. The purpose of this follow-up study was to assess whether this exercise intervention had long-lasting effects in reducing injurious falls and fractures. DESIGN: five-year health-care register-based follow-up study after a 1-year, four-arm RCT. SETTING: community-dwelling older women in Finland. SUBJECTS: one hundred and forty-five of the original 149 RCT participants; women aged 70-78 years at the beginning. METHODS: participants' health-care visits were collected from computerised…
Force Platform Balance Measures as Predictors of Indoor and Outdoor Falls in Community-Dwelling Women Aged 63-76 Years
2008
Background. Inability to maintain balance while standing increases risk of falls in older people. The present study assessed whether center of pressure (COP) movement measured with force platform technology predicts risk for falls among older people with no manifest deficiency in standing balance. Methods. Participants were 434 community-dwelling women, aged 63-76 years. COP was measured in six stances on a force platform. Following balance tests, participants reported their falls with 12 monthly calendars. Incidence rate ratios (IRR) with 95% confidence intervals (CI) were computed from negative binomial regression models. For the analysis, those with>/=1 fall indoors were coded"indoor fal…
Poor vision accompanied with other sensory impairments as a predictor of falls in older women
2008
Objectives:we studied visual acuity (VA) and co-existing hearing impairment and poor standing balance as predictors of falls. Design: prospective study with 1-year follow-up. Setting: research laboratory and residential environment. Participants: 428 women aged 63‐76 years from the Finnish Twin Study on Aging. Measurements: participants were followed up for incidence of falls over 1 year. VA, hearing ability and standing balance were assessed at the baseline. The incidence rate ratios (IRR) for falls were computed using the negative binomial regression model. Results: during the follow-up, 47% of participants experienced a fall. After adjusting for age and interdependence of twin sisters, p…
Importance of Personality for Objective and Subjective-Physical Health in Older Men and Women
2020
Objective and subjective health generally have a positive relationship, although their association may be moderated by factors such as gender and personality. We aimed to analyze the association between personality and objective (metabolic syndrome (MetS)) and subjective-physical health in older men and women. For this purpose, in 138 participants (53.6% women, Mage = 66.85), neuroticism, conscientiousness, extraversion, openness, and agreeableness (NEO Five Factor Inventory), subjective-physical health (Short Form Health Survey, SF-36), and MetS (employing waist circumference, blood pressure, triglycerides, high-density lipoprotein cholesterol, and glycated hemoglobin) were assessed. Logis…
Can personality predict retirement behaviour? A longitudinal analysis combining survey and register data from Norway.
2017
Published version of an article in the journal: European Journal of Ageing. Also available from the publisher at: http://dx.doi.org/10.1007/s10433-011-0212-6 This study investigates how far personality can predict the timing and routes of people’s retirement. It uses a large comprehensive Norwegian survey, with larger sample size than earlier related studies, providing estimates of personality based on the five-factor model. The survey data are matched with administrative data, allowing observations of retirement over the 2002–2007 period. The analysis distinguishes between the disability and the non-disability retirements. Retirement is investigated using discrete time, competing risk, log…
How Universal Is the Relationship between Remotely Sensed Vegetation Indices and Crop Leaf Area Index? A Global Assessment
2016
This study aims to assess the relationship between Leaf Area Index (LAI) and remotely sensed Vegetation Indices (VIs) for major crops, based on a globally explicit dataset of in situ LAI measurements over a significant set of locations. We used a total of 1394 LAI measurements from 29 sites spanning 4 continents and covering 15 crop types with corresponding Landsat satellite images. Best-fit functions for the LAI-VI relationships were generated and assessed in terms of crop type, vegetation index, level of radiometric/atmospheric processing, method of LAI measurement, as well as the time difference between LAI measurements and satellite overpass. These global LAI-VI relationships were evalu…
Determinants of elite-level air rifle shooting performance
2015
This study focused on identifying the most important factors determining performance in elite-level air rifle shooting technique. Forty international- and national-level shooters completed a simulated air rifle shooting competition series. From a total of 13 795 shots in 319 tests, shooting score and 17 aiming point trajectory variables were measured with an optoelectronic device and six postural balance variables were measured with force platform. Principal component analysis revealed six components in the air rifle shooting technique: aiming time, stability of hold, measurement time, cleanness of triggering, aiming accuracy, and timing of triggering. Multiple regression analysis identifie…
Dynamics of the general factor of personality: A predictor mathematical tool of alcohol misuse
2020
[EN] There are few studies developed about the general factor of personality (GFP) dynamics. This paper uses a dynamical mathematical model, the response model, to predict the short-term effects of a dose of alcohol on GFP and reports the results of an alcohol intake experiment. The GFP dynamical mechanism of change is based on the unique trait personality theory (UTPT). This theory proposes the existence of GFP, which occupies the apex of the hierarchy of personality. An experiment with 37 volunteers was performed. All the participants completed The five-adjective scale of the general factor of personality (GFP-FAS) in trait-format (GFP-T) and state-format (GFP-S) before alcohol consumptio…