Search results for "regulation"

showing 10 items of 4463 documents

Réseaux de distribution de l’énergie et sobriété énergétique des territoires, les apports d’une approche thermodynamique et métabolique des systèmes …

2017

Dans le contexte de transition énergétique et de crise environnementale actuel, les intérêts des approches territoriales et systémiques de l’énergie semblent aujourd’hui admis. Cependant et malgré les nombreuses avancées dans les domaines technologiques, en matière d’urbanisme et d’aménagement ou bien encore en termes d’approches psycho-sociales et comportementales, les courbes de consommations énergétiques peinent à s’infléchir. Fort de ce constat, nous posons l’hypothèse, sur la base d’éléments théoriques empruntés à la thermodynamique et à la biologie, du rôle potentiel que pourraient jouer les réseaux de distribution énergétique, leurs caractéristiques, leur morphologie et leur dynamiqu…

métabolisme territorialSocial Sciences and Humanitiesréseaux énergétiques020209 energy0211 other engineering and technologies02 engineering and technologyterritorial metabolism[ SHS.GEO ] Humanities and Social Sciences/Geography[ SDE ] Environmental Sciencesreseaux energétiquesthermodynamicsobriété énergétiquerégulation0202 electrical engineering electronic engineering information engineeringrational use of energyenergy networksGE1-350thermodynamiquelcsh:Environmental scienceslcsh:GE1-350Régulation021107 urban & regional planningregulation[SHS.GEO]Humanities and Social Sciences/GeographyEnvironmental sciences13. Climate actionSciences Humaines et Sociales
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Internet two sided market regulation: A zero-ratong analysis from a theoretical and experimental approach

2022

El objetivo de esta tesis es estudiar las prácticas discriminatorias empleadas en el Mercado de Internet. Dichas prácticas han sido reguladas por la neutralidad de red en medio de un amplio y polémico debate político, económico y técnico. Con esta investigación, hemos querido analizar los efectos de los servicios de zero-rating desde una perspectiva teórica y experimental. Así mismo, proponemos un replanteamiento de la neutralidad de red a través de un estudio experimental que replica las interacciones entre agentes en el actual ecosistema digital. Capítulo 2: El objetivo de este capítulo es estudiar el efecto de los contratos de zero-rating en un mercado bilateral de duopolio de Internet. …

net neutralityUNESCO::CIENCIAS ECONÓMICAStwo-sided market:CIENCIAS ECONÓMICAS [UNESCO]internet regulationzero-ratingvertical integration
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The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model

2020

2-Methoxyestradiol is one of the natural 17&beta

neuronal nitric oxide synthaseProgrammed cell death2-methoxyestradiolLactams MacrocyclicAntineoplastic AgentsBone NeoplasmsModels BiologicalArticleCatalysisHsp90 inhibitorNitric oxidelcsh:ChemistryInorganic Chemistrychemistry.chemical_compoundDownregulation and upregulationosteosarcomaHeat shock proteinBenzoquinonesAnimalsHumansDrug InteractionsHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsPhysical and Theoretical Chemistrygeldanamycinlcsh:QH301-705.5Molecular BiologySpectroscopyAntibiotics AntineoplasticbiologyOrganic ChemistryGeneral MedicineGeldanamycinHsp90Computer Science ApplicationsHsp70lcsh:Biology (General)lcsh:QD1-999chemistryCancer researchbiology.proteinInternational Journal of Molecular Sciences
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Post-Publication Gatekeeping Factors and Practices: Data, Platforms, and Regulations in News Work

2023

The gatekeeping literature has turned to look at the factors and practices that shape gatekeeping in the post-publication environment, i.e., after news has entered circulation. This article adds to the discussion and argues that news workers share gatekeeping power in the post-publication environment with audiences, platforms, and regulations. Further, this study extends the post-publication gatekeeping framework and considers it in the context of datafication. The article aims to broadly understand how (audience) data is part of editorial decision-making in news media from news workers’ perceptions. The current study was conducted by interviewing news workers from three Finnish news organi…

news workersuutisettoimittajat (media)Communicationpäätöksentekososiaalinen mediatoimitustyöaudiencesyleisödataplatformsregulationsgatekeepingjournalismidataficationMedia and Communication
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The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) and its Role in Conservation of Cacti and Other Succulent…

2007

The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) contributes to nature conservation by regulating international trade in listed species by means of a permit system. Through this control system all parties assist in maintaining the listed rare and threatened species in the wild. CITES allows trade in wild specimens up to a level that is not detrimental for the survival of the species in the wild, that is, a use of nature commonly referred to as sustainable use. The basis of CITES are discussed with special emphasis on the Cactaceae and other succulent plants included in the Convention. The framework of regulation of plants in trade is outlined and t…

non-detrimentregulationBiodiversitylegislationsustainable usepolicy
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Reputation, regulation and corporate governance as determinants of the improvement of non-financial information (NFI) reporting

2023

Many years have passed since corporate social responsibility (CSR) and the disclosure of non-financial information (NFI) aroused interest in very few organizations (Hąbek & Wolniak, 2016). Today, they are part of the main priorities for the most important companies in the world, and they are seen as an important part of the strategy due to the many benefits associated with them (Castilla-Polo & Sánchez-Hernández, 2020). In the last decades, it has become evident the relevance that NFI reporting has worldwide. It can be seen through the evolution of the issuance of this type of reports. In 2002, 45% of the G250 companies published a separate report, 20 years later, the numbers show that 96% …

non-financial information reportingcorporate governanceregulationreputationUNESCO::CIENCIAS ECONÓMICASsustainability reports
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The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms.

2015

Objectives:\ud The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.\ud \ud Methods:\ud Pharmacological manipulation of the activity of CRF receptors, CRF1 and CRF2, was performed in 3T3L1 white pre-adipocytes and T37i brown pre-adipocytes during in vitro differentiation. The expression of genes of the CRF/urocortin system and of markers of white and brown adipocytes was evaluated along with mitochondrial biogenesis and cellular oxygen consumption. Metabolic evaluation of corticosterone-deficient or supplemented Crhr1-null (Crhr1−/−) mice and their wild-type controls was performed alo…

obesitycrf1Corticotropin-Releasing Hormonecrf2Endocrinology Diabetes and MetabolismIMPAIRED STRESS-RESPONSE[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionAdipocytes WhiteMedicine (miscellaneous)urocortinWhite adipose tissueMOUSEMicebrown adiposte tissue0302 clinical medicineBrowningUrocortinsUrocortin0303 health sciencesNutrition and Dietetics[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismParacrine mechanisms[ SDV.MHEP.EM ] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismImmunohistochemistryADIPOCYTESAdipocytes BrownADIPOSE-TISSUESKELETAL-MUSCLEhormones hormone substitutes and hormone antagonistsSignal TransductionEXPRESSIONmedicine.medical_specialtyendocrine systemTHERMOGENESISBiologycrfReceptors Corticotropin-Releasing Hormone03 medical and health scienceswhite adipose tissueInternal medicine3T3-L1 CellsmedicineAnimalsRNA MessengerGLUCOCORTICOIDS030304 developmental biologyENERGY HOMEOSTASISCorticotrophin releasing factoradipose plasticityPigments BiologicalUROCORTIN-II GENEQPEndocrinologyGene Expression Regulation[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgery
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High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice

2021

In the large GWAS studies, NEGR1 gene has been one of the most significant gene loci for body mass phenotype. The purpose of the current study was to clarify the role of NEGR1 in the maintenance of systemic metabolism, including glucose homeostasis, by using both male and female Negr1−/− mice receiving a standard or high fat diet (HFD). We found that 6 weeks of HFD leads to higher levels of blood glucose in Negr1−/− mice. In the glucose tolerance test, HFD induced phenotype difference only in male mice

obesitymedicine.medical_specialtyQH301-705.5Medicine (miscellaneous)BiologyArticleGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundDownregulation and upregulationgenetic modelsInternal medicineGenetic modelmedicineGlucose homeostasisBiology (General)Fatty acid synthesisGlucose tolerance testmedicine.diagnostic_testnutritional and metabolic diseasesMetabolismmetabolic diseasemetabolomicsNegr1Protein catabolismEndocrinologyglucose intoleranceGluconeogenesischemistry<i>Negr1</i>Biomedicines
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Clinical justification of dental radiology in adult patients: A review of the literature

2007

Although the radiological doses used by dentists are low individually, patients are often exposured to many repeat dental radiographic examinations. The ‘routine’ use of dental radiography, such as screening of all patients using dental panoramic radiography (DPRs) or a random decision to take a dental radiograph, will inevitable lead to unnecessary patient exposure. The use of Radiographic Referral Criteria has now become a legal requirement for all practitioners following the adoption of European Legislation. All exposures to x-rays should be clinically justified and each exposure should be expected to give the patient a positive net benefit. Recently the European Commission has published…

odontologíaRadiation protectiondentistryregulationsGuías europeasradiología dentalUNESCO::CIENCIAS MÉDICASdental radiologylegislación:CIENCIAS MÉDICAS [UNESCO]European guidelinesProtección radiológica
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Assessment of genetically modified oilseed rape MS8, RF3 and MS8×RF3 for renewal of authorisation under regulation (EC) No 1829/2003 (application EFS…

2017

Efsa Panel On Genetically Modified Organisms (gmo)Opinion scientificRequestor: European CommissionQuestion number: EFSA-Q-2016-00569; Following the submission of application EFSA-GMO-RX-004 under Regulation (EC) No 1829/2003 from Bayer CropScience, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a scientific risk assessment on the data submitted in the context of the renewal of authorisation application of the genetically modified (GM) herbicide-tolerant oilseed rape MS8, RF3 and MS89RF3. The data received in the context of this renewal application contain post-market environmental monitoring reports, systematic searches and…

oilseed rapeoilseed rape;MS8;RF3 and MS89RF3;renewal;articles 11 and 23;Regulation (EC) No 1829/2003040301 veterinary sciencesgmo[SDV]Life Sciences [q-bio]Veterinary (miscellaneous)ogmContext (language use)Plant Science010501 environmental sciencesOriginal ApplicationMS801 natural sciencesMicrobiologyarticles 11 and 230403 veterinary sciencearticles 11 and 23RF3 and MS8×RF30105 earth and related environmental sciencesoilseedrenewal2. Zero hungerbusiness.industryRegulation (EC) No 1829/2003Authorization10079 Institute of Veterinary Pharmacology and Toxicology04 agricultural and veterinary sciencesFood safetyBiotechnologyGenetically modified organismRF3 and MS89RF3Scientific OpinionRF3 and MS8xRF3Regulation (EC) No1829/2003570 Life sciences; biologygraine oléagineuseAnimal Science and ZoologyParasitologybusinessRisk assessmentRegulation (EC) No 1829/2003Food Science
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