Search results for "relation"

showing 10 items of 10542 documents

Spectrofluorimetric Quantification of Malondialdehyde for Evaluation of Cyclooxygenase-1/Thromboxane Synthase Inhibition

1999

The in vitro assay developed by Hartmann and Ledergerber (1995) utilizing the spectrofluorimetric quantification of malondialdehyde after reaction with thiobarbituric acid was modified and used for further investigations. The human whole blood was replaced by a platelet suspension of pig blood, and calcium ionophore A23187 was used instead of collagen for inducing the arachidonic acid cascade. The modified assay represents a simple, time and cost saving method for the evaluation of cyclooxygenase-1/thromboxane synthase inhibition. The reproducibility and comparability of results is given. Additional experiments allow classification of selective phospholipase A2, cyclooxygenase-1, and thromb…

Blood PlateletsSwineThiobarbituric acidPharmaceutical ScienceCyclooxygenase pathwaychemistry.chemical_compoundPhospholipase A2MalondialdehydeDrug DiscoveryAnimalsHumansCyclooxygenase InhibitorsDrug InteractionsPlateletEnzyme InhibitorsDose-Response Relationship DrugbiologyImidazolesMembrane ProteinsReproducibility of ResultsThiobarbituratesMalondialdehydeIsoenzymesSpectrometry FluorescencechemistryBiochemistryProstaglandin-Endoperoxide SynthasesCyclooxygenase 1biology.proteinArachidonic acidThromboxane-A SynthaseThromboxane-A synthaseCyclooxygenaseArchiv der Pharmazie
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Comparison between rectal and body surface temperature in dogs by the calibrated infrared thermometer

2020

Highlights • Dogs poorly tolerate rectal temperature measurements with a contact thermometer. • Existing alternative approaches used uncalibrated infrared thermometers. • Gum and inguinal temperature are correlated moderately to rectal temperature. • Hyperthermia was detected with sensitivity and specificity up to 90.0% and 78.6%. • Future studies should include a calibrated thermometer and control external factors.

Body surface temperatureHyperthermiaMaterials scienceCorrelation coefficient040301 veterinary sciencesBody surface temperatureInfrared thermometerRectal temperatureArticleHealth status0403 veterinary scienceDogmedicinelcsh:Veterinary medicineGeneral Veterinarybusiness.industry0402 animal and dairy science04 agricultural and veterinary sciencesGold standard (test)Hypothermiamedicine.disease040201 dairy & animal scienceInfrared thermometerThermometerlcsh:SF600-1100Animal Science and Zoologymedicine.symptomSnoutNuclear medicinebusinessVeterinary and Animal Science
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An ab initio study of the tautomeric equilibria of the N-oxides of hydroxypyridines in the vapour phase

1993

Abstract An ab initio self-consistent field molecular orbital study of the N-oxides of hydroxypyridines has been carried out. The optimized structures have been obtained at the 6-31G ∗ level, and the energy values have been computed at the 6-31G ∗ and MP2-6-31G ∗ //6-31G ∗ levels. The tautomerization energies for the three couples of systems in the vapour phase have been evaluated.

Bond lengthMolecular geometryElectronic correlationChemistryAb initio quantum chemistry methodsComputational chemistryPhase (matter)Ab initioMolecular orbitalPhysical and Theoretical ChemistryCondensed Matter PhysicsBiochemistryTautomerJournal of Molecular Structure: THEOCHEM
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A theoretical determination of the dissociation energy of the nitric oxide dimer

1994

Multi-reference CI methods have been applied to determine the dissociation energy and structure of thecis-N2O2 molecule. The convergence of the theoretical result has been checked with respect to a systematic expansion of the one-electron basis set and the multi-reference CI wave function. The best calculated value, 13.8 kJ/mol, is in agreement with the experimental value, 12.2 kJ/mol. It has been obtained with an extended ANO-type basis set [6s5p3d2f], including the effect of the basis set superposition error (BSSE) in the geometry optimization, and additional effects, such as the electron correlation of core electrons and relativistic corrections, using the average coupled pair functional…

Bond lengthPhysicsMolecular geometryElectronic correlationCore electronAb initio quantum chemistry methodsThermodynamicsChiropracticsPhysical and Theoretical ChemistryConfiguration interactionBond-dissociation energyBasis setTheoretica Chimica Acta
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Analysis of the CIPSI/DCCI approach to characterize the HF AND F2 single bond

1990

Abstract The aim of the present work is to account for the main differential correlation contributions occurring during the bond breaking process of HF and F2 molecules in an accurate and inexpensive way. Starting from the dissociation-consistent configuration interaction (DCCI) scheme by Goddard and co-workers the corresponding contributions are evaluated within the framework reported by Malrieu and co-workers, namely configuration interaction by perturbation with multiconfigurational zeroth-order wavefunction selected by iterative process (CIPSI). In addition, the DCCI scheme has been improved by introducing the dispersion effects associated with the valence MOs adjacent to the bond. The …

Bond lengthValence (chemistry)Electronic correlationComputational chemistryChemistryGeneral Physics and AstronomySingle bondElectronic structurePhysical and Theoretical ChemistryConfiguration interactionWave functionMolecular physicsDiatomic moleculeChemical Physics
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Diagnostic efficacy of panoramic mandibular index to identify postmenopausal women with low bone mineral densities

2011

Objectives: The aim of the study was to compare and assess the accuracy of panoramic mandibular index (PMI) and antegonial index (AI) in the panoramic radiographs of postmenopausal women with normal and low skeletal bone mineral densities( BMD) diagnosed by using dual energy x-ray absorptiometry ( DXA). Study Design: In panoramic radiographs obtained from 40 post menopausal women( 20 normal and 20 osteoporo tic) aged between 50-75 who’s BMD has already been assessed by a DXA, the mean was calculated for PMI and AI index values measured in the right and left mandibles. The PMI and AI index values were evaluated using the student’s t test. The correlation between the observers for indices was…

Bone mineralIndex (economics)Receiver operating characteristicbusiness.industryRadiographyOsteoporosisDentistryOdontología:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludConfidence intervalPearson product-moment correlation coefficientsymbols.namesakeStandard errorUNESCO::CIENCIAS MÉDICASsymbolsmedicinebusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
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Emergence of statistically validated financial intraday lead-lag relationships

2014

According to the leading models in modern finance, the presence of intraday lead-lag relationships between financial assets is negligible in efficient markets. With the advance of technology, however, markets have become more sophisticated. To determine whether this has resulted in an improved market efficiency, we investigate whether statistically significant lagged correlation relationships exist in financial markets. We introduce a numerical method to statistically validate links in correlation-based networks, and employ our method to study lagged correlation networks of equity returns in financial markets. Crucially, our statistical validation of lead-lag relationships accounts for mult…

Bootstrap methodFinancial market01 natural sciencesLead-lag correlation010305 fluids & plasmasFOS: Economics and businessCorrelationSettore SECS-S/06 -Metodi Mat. dell'Economia e d. Scienze Attuariali e Finanz.Statistically validated network0502 economics and business0103 physical sciencesStatisticsEconomicsEconometricsStock (geology)FinanceStatistical Finance (q-fin.ST)050208 financeHigh-frequency databusiness.industry05 social sciencesFinancial marketMarket efficiencyEquity (finance)Quantitative Finance - Statistical FinanceStock returnSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Economics Econometrics and Finance (all)2001 Economics Econometrics and Finance (miscellaneous)Multiple comparisons problemLead–lag compensatorbusinessGeneral Economics Econometrics and FinanceTransaction dataFinanceQuantitative Finance
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The Border Effect in Spain

2005

This paper analyses the border effect in Spain using a unique dataset on intranational trade flows over the period 1995–98. The results indicate that, after controlling for market size and distance, Spanish regions trade around 22 times more with the rest of Spain than they do with OECD countries. Moreover, the size of the Spanish bias is lower in the case of the Spanish regions’ exports than in the case of imports, although the difference is not statistically significant in most cases. Finally, the border effect is not uniform across Spanish regions.

Border effectEconomics and EconometricsAccountingRest (finance)Political Science and International RelationsMarket sizeEconomicsOecd countriesInternational economicsFinanceThe World Economy
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Is the Border Effect an Artefact of Geographical Aggregation?

2011

The existence of a large border effect is considered as one of the main puzzles of international macroeconomics. We show that the border effect is, to a large extent, an artefact of geographic concentration. In order to do so we combine international flows with intra-national flows data characterised by a high geographic grid. At this fine grid, intra-national flows are highly localised and dropping sharply with distance. The use of a small geographical unit of reference to measure intra-national bilateral trade flows allows to estimating correctly the negative impact of distance on shipments. When we use sector disaggregated export flows of 50 Spanish provinces in years 2000 and 2005 split…

Border effectEconomics and EconometricsBilateral tradeGeographyOrder (exchange)AccountingPolitical Science and International RelationsEconometricsInternational economicsGridFinanceInternational financeUnit (housing)The World Economy
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Development of an Easily Bioconjugatable Water-Soluble Single-Photon Emission-Computed Tomography/Optical Imaging Bimodal Imaging Probe Based on the …

2021

A water-soluble fluorescent aza-BODIPY platform (Wazaby) was prepared and functionalized by a polyazamacrocycle agent and a bioconjugable arm. The resulting fluorescent derivative was characterized and bioconjugated onto a trastuzumab monoclonal antibody as a vector. After bioconjugation, the imaging agent appeared to be stable in serum (>72 h at 37 °C) and specifically labeled HER-2-positive breast tumors slices. The bioconjugate was radiolabeled with [111In] indium and studied in vivo. The developed monomolecular multimodal imaging probe (MOMIP) is water-soluble and chemically and photochemically stable, emits in the near infrared (NIR) region (734 nm in aqueous media), and displays a goo…

Boron CompoundsFluorescence-lifetime imaging microscopyFluorophoreMice NudeQuantum yieldBreast Neoplasms01 natural sciencesMiceStructure-Activity Relationship03 medical and health scienceschemistry.chemical_compound0302 clinical medicineNuclear magnetic resonanceDrug DevelopmentIn vivoDrug DiscoveryAnimalsHumansFluorescent DyesTomography Emission-Computed Single-PhotonBioconjugationDose-Response Relationship DrugMolecular Structure010405 organic chemistryOptical ImagingNear-infrared spectroscopyAntibodies MonoclonalMammary Neoplasms ExperimentalWaterHep G2 CellsFluorescenceImaging agent0104 chemical sciences3. Good healthSolubilitychemistry030220 oncology & carcinogenesisMolecular MedicineFemaleJournal of Medicinal Chemistry
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