Search results for "relationship"

Low Grade Inflammation as a Common Pathogenetic Denominator in Age-Related Diseases: Novel Drug Targets for Anti-Ageing Strategies and Successful Age…

2010

Nowadays, people are living much longer than they used to do, however they are not free from ageing. Ageing, an inexorable intrinsic process that affects all cells, tissues, organs and individuals, is a post-maturational process that, due to a diminished homeostasis and increased organism frailty, causes a reduction of the response to environmental stimuli and, in general, is associated to an increased predisposition to illness and death. However, the high incidence of death due to infectious, cardiovascular and cancer diseases underlies a common feature in these pathologies that is represented by dysregulation of both instructive and innate immunity. Several studies show that a low-grade s…

Book Review: Properties of Chemically Interesting Potential Energy Surfaces.(Series: Lecture Notes in Chemistry, Vol. 56.) By D. Heidrich, W. Kleisch…

1993

On estimating contemporaneous quarterly regional GDP

2007

Subnational regional jurisdictions rarely have at their disposal a reasonable array of timely statistics to monitor their economic condition. In light of this, we develop a procedure that simultaneously estimates a quarterly time series for all regions of a country based upon quarterly national and annual regional data. While other such techniques exist, we suggest a temporal error structure that eliminates possible spurious jumps. Using our approach, regional analysts should now be able to distribute national growth among regions as soon as quarterly national figures are released. In a Spanish application, we detail some practicalities of the process and show that our proposal produces bet…

Assessing changes in rainfall erosivity in Sicily during the twentieth century

2007

Changes in rainfall erosivity are an expected consequence of climate change. Long-term series of the single storm erosion index, EI, may be analysed to detect trends in rainfall erosivity. An indirect approach has to be applied for estimating EI, given that long series of rainfall intensities are seldom available. In this paper, a method for estimating EI from the corresponding rainfall amount, he, was developed for Sicily. This method was then applied at 17 Sicilian locations, representative of different climatic zones of the region, to generate a long series (i.e. from 1916 to 1999 in most cases) of EI values. Linear and step (step located at 1970) trends in annual and seasonal erosivity …

Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.

1999

The distribution of tricyclic antidepressants from plasma to brain, where these drugs exert their main clinical action, and other organs is related to transport events across the cell membranes of the different tissues. It could be expected that all the molecular features that condition the transport processes (mainly hydrophobicity and molar total charge) also control the pharmacokinetic and biochemical behavior. Micellar liquid chromatography (MLC) has been proposed to emulate in vitro the partitioning process in the biomembranes. The use of micellar solutions of Brij35 as mobile phases in reversed-phase liquid chromatography has proven to be valid to predict the biological activities of …

Epidemiological analysis of Salmonella enterica from beef sampled in the slaughterhouse and retailers in Dakar (Senegal) using pulsed-field gel elect…

2007

Seventy-eight isolates of Salmonella spp. isolated from beef sampled from the official city slaughterhouse and from retailers in Dakar, Senegal were analyzed using serotyping, antimicrobial testing and macrorestriction profiling by Pulsed-Field Gel Electrophoresis (PFGE). These analyses were done to identify clonal relationships and potential transmission routes in beef channel. XbaI macrorestriction allowed defining 17 genotypes among the six main analyzed serotypes: Salmonella bredeney (3 genotypes), S. muenster (6), S. waycross (1), S. corvallis (3), S. kentucky (1) and S. brandenburg (3). The cross analysis of PFGE profiles and origin of the beef samples reveals a wide range of contamin…

Linking functional and relational service quality to customer satisfaction and loyalty: differences between men and women.

2010

This study assessed differences between men and women in the association of perceptions of service quality with customer evaluations. Functional (efficiency with which the service is delivered) and relational (customers' emotional benefits, beyond the core performance, related to the social interaction of customers with employees) dimensions of service quality were measured as well as customer satisfaction and loyalty. The sample of 277 customers (191 men, 86 women), surveyed in 29 Mexican hotels, had a mean age of 38.1 yr. ( SD = 9.7) for men and 34.5 yr. ( SD = 11.0) for women. To be eligible for survey, customers had to have spent at least one night in the hotel in question. Analysis in…

I love you, but you let me down! How hate and retaliation damage customer-brand relationship

2022

The literature on the dark side of the customer-brand relationship is still evolving. Admittedly, scholars have given it noteworthy attention in the recent past, yet gaps persist related to the products and services, antecedents, and consequents examined. Our study augments the understanding of the negative aspects of the customer-brand relationship by examining brand hate and betrayal as its two manifestations. Using online food delivery (OFD) platforms as the product/service under focus, we employ a mixed-method approach to identify the negative experiences (i.e., safety and hygiene grievances, dissatisfaction, negative word of mouth, and advertisement overload) that could stimulate the n…

Value, supplier dependence and long‐term orientation

2011

PurposeIn organizational markets, many companies tend to reduce the number of providers to focus on establishing relationships with few of them. The purpose of this paper is to analyze the influence of relationship value and dependence of supplier on long‐term orientation and customer loyalty in the setting of relationships between travel agencies and their main providers.Design/methodology/approachA partial least square regression is performed to test a proposed model that links several relational variables with outcomes in terms of customer loyalty.FindingsResults provide support for the positive indirect influence of relationship value on long‐term orientation, while customer dependence …

Systemic Development of Service Innovation

2015

This chapter explores the intrinsic characteristics of services and service systems and presents systemic approach to produce service innovations. The chapter consists of elaborating the characteristics of services and the principles of systemic development, discussing service matrixes, service systems, service strategies and business models, and special challenges related to the development of services and service innovations. Services are always produced in service systems consisting of combination of service personnel and information systems. Customers are involved in these systems by interacting with the front end of service organization. The key issue in service development and innovat…