Search results for "repeats"

showing 10 items of 209 documents

A brief history of the formation of DNA databases in forensic science within Europe.

2001

The introduction of DNA analysis to forensic science brought with it a number of choices for analysis, not all of which were compatible. As laboratories throughout Europe were eager to use the new technology different systems became routine in different laboratories and consequently, there was no basis for the exchange of results. A period of co-operation then started in which a nucleus of forensic scientists agreed on an uniform system. This collaboration spread to incorporate most of the established forensic science laboratories in Europe and continued through two major changes in the technology. At each step agreement was reached on which systems to use. From the beginning it was realise…

Databases FactualInternational CooperationLegislationMinisatellite RepeatsBiologycomputer.software_genrePolymerase Chain ReactionSensitivity and SpecificityPathology and Forensic MedicineDNA databaseCrime sceneHumansEthics MedicalDatabaseHistorical ArticleForensic MedicineHistory 20th CenturyDNA FingerprintingForensic scienceEuropeDNA profilingLawcomputerNational DNA databaseNucleic Acid Amplification TechniquesPolymorphism Restriction Fragment LengthCriminal justiceForensic science international
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On Sturmian Graphs

2007

AbstractIn this paper we define Sturmian graphs and we prove that all of them have a certain “counting” property. We show deep connections between this counting property and two conjectures, by Moser and by Zaremba, on the continued fraction expansion of real numbers. These graphs turn out to be the underlying graphs of compact directed acyclic word graphs of central Sturmian words. In order to prove this result, we give a characterization of the maximal repeats of central Sturmian words. We show also that, in analogy with the case of Sturmian words, these graphs converge to infinite ones.

Discrete mathematicsApplied MathematicsCDAWGsContinued fractionsSturmian wordSturmian wordsCharacterization (mathematics)RepeatsDirected acyclic graphCombinatoricsIndifference graphSturmian words CDAWGs Continued fractions RepeatsChordal graphComputer Science::Discrete MathematicsDiscrete Mathematics and CombinatoricsContinued fractionWord (group theory)Computer Science::Formal Languages and Automata TheoryReal numberMathematics
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Temporal relationship between genetic and warning signal variation in the aposematic wood tiger moth (Parasemia plantaginis).

2013

Many plants and animals advertise unpalatability through warning signals in the form of colour and shape. Variation in warning signals within local populations is not expected because they are subject to directional selection. However, mounting evidence of warning signal variation within local populations suggests that other selective forces may be acting. Moreover, different selective pressures may act on the individual components of a warning signal. At present, we have a limited understanding about how multiple selection processes operate simultaneously on warning signal components, and even less about their temporal and spatial dynamics. Here, we examined temporal variation of several w…

EstoniaGenetic MarkersMaleAposematismMothsSignalDNA MitochondrialSpatio-Temporal AnalysisGene FrequencyParasemia plantaginisGeneticsAnimalsWings AnimalSelection GeneticEcology Evolution Behavior and SystematicsSelection (genetic algorithm)FinlandCell NucleusWingbiologyDirectional selectionEcologyPigmentationGenetic VariationSequence Analysis DNAbiology.organism_classificationVariation (linguistics)Genetics PopulationPhenotypeEvolutionary biologyGenetic structureta1181Microsatellite RepeatsMolecular ecology
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Phylogeography of a Habitat Specialist with High Dispersal Capability: The Savi’s Warbler Locustella luscinioides

2012

In order to describe the influence of Pleistocene glaciations on the genetic structure and demography of a highly mobile, but specialized, passerine, the Savi's Warbler (Locustella luscinioides), mitochondrial DNA sequences (ND2) and microsatellites were analysed in c.330 individuals of 17 breeding and two wintering populations. Phylogenetic, population genetics and coalescent methods were used to describe the genetic structure, determine the timing of the major splits and model the demography of populations. Savi's Warblers split from its sister species c.8 million years ago and have two major haplotype groups that diverged in the early/middle Pleistocene. One of these clades originated in…

Evolutionary Genetics0106 biological sciencesAnimal EvolutionPopulation Dynamicslcsh:MedicinePopulation genetics01 natural sciencesCoalescent theoryWarblerSongbirdslcsh:ScienceGenome EvolutionPhylogenyLikelihood FunctionsPrincipal Component Analysis0303 health scienceseducation.field_of_studyMultidisciplinarybiologyGenomicsEuropePhylogeographyGenetic structureResearch ArticleGene FlowMolecular Sequence DataPopulationDNA Mitochondrial010603 evolutionary biology03 medical and health sciencesAnimalsEvolutionary SystematicseducationBiologyEcosystemDemography030304 developmental biologyAnalysis of VarianceEvolutionary BiologyBase SequenceModels Geneticlcsh:RComputational BiologyLocustella luscinioidesBayes TheoremSequence Analysis DNAbiology.organism_classificationOrganismal EvolutionPhylogeographyGenetics PopulationHaplotypesEvolutionary biologyBiological dispersallcsh:QAnimal MigrationGenome Expression AnalysisPopulation GeneticsMicrosatellite RepeatsPLoS ONE
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Genetic and Ecotypic Differentiation in a Californian Plant Polyploid Complex (Grindelia, Asteraceae)

2014

Studies of ecotypic differentiation in the California Floristic Province have contributed greatly to plant evolutionary biology since the pioneering work of Clausen, Keck, and Hiesey. The extent of gene flow and genetic differentiation across interfertile ecotypes that span major habitats in the California Floristic Province is understudied, however, and is important for understanding the prospects for local adaptation to evolve or persist in the face of potential gene flow across populations in different ecological settings. We used microsatellite data to examine local differentiation in one of these lineages, the Pacific Coast polyploid complex of the plant genus Grindelia (Asteraceae). W…

Evolutionary GeneticsMarshPlant EvolutionSpeciationlcsh:MedicinePlant ScienceCaliforniaGene flowPloidyMolecular SystematicsNatural Selectionlcsh:ScienceFlowering Plantseducation.field_of_studyMultidisciplinarygeography.geographical_feature_categoryGeographyEcotypeEcologyfood and beveragesPolyploid complexPlantsBiological EvolutionHabitatResearch ArticleGene FlowEvolutionary ProcessesGrindeliaGenotypeGeneral Science & TechnologyPopulationParallel EvolutionBiologyPolyploidyGrindeliaEvolutionary Adaptationparasitic diseasesGeneticsEvolutionary SystematicseducationHybridizationTaxonomyLocal adaptationEcotypeEvolutionary BiologygeographyPopulation Biologylcsh:ROrganismsBiology and Life SciencesGeobotanyPlant Taxonomybiology.organism_classificationOrganismal EvolutionGenetic Locilcsh:QPopulation GeneticsMicrosatellite RepeatsPLoS ONE
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Localization of non-specific X-linked mental retardation gene (MRX73) to Xp22.2.

2001

Clinical and molecular studies are reported on a family (MRX73) of five males with non-specific X-linked mental retardation (XLMR). A total of 33 microsatellite and RFLP markers was typed. The gene for this XLMR condition was been linked to DXS1195, with a lod score of 2.36 at theta = 0. The haplotype and multipoint linkage analyses suggest localization of the MRX73 locus to an interval of 2 cM defined by markers DXS8019 and DXS365, in Xp22.2. This interval contains the gene of Coffin-Lowry syndrome (RSK2), where a missense mutation has been associated with a form of non-specific mental retardation. Therefore, a search for RSK2 mutations was performed in the MRX73 family, but no causal muta…

Family HealthMaleGeneticscongenital hereditary and neonatal diseases and abnormalitiesCoffin–Lowry syndromeX ChromosomeGenetic LinkageHaplotypeChromosome MappingLocus (genetics)Biologymedicine.diseasePedigreeGenetic linkageIntellectual DisabilitymedicineHumansMissense mutationMicrosatelliteFemaleLod ScoreRestriction fragment length polymorphismGenetics (clinical)X chromosomeMicrosatellite Repeats
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Absence of spatial genetic structure in common dentex (Dentex dentex Linnaeus, 1758) in the Mediterranean Sea as evidenced by nuclear and mitochondri…

2018

International audience; The common dentex, Dentex dentex, is a fish species which inhabits marine environments in the Mediterranean and Northeast Atlantic regions. This is an important species from an ecological, economic and conservation perspective, however critical information on its population genetic structure is lacking. Most samples were obtained from the Mediterranean Sea (17 sites) with an emphasis around Corsica (5 sites), plus one Atlantic Ocean site. This provided an opportunity to examine genetic structuring at local and broader scales to provide science based data for the management of fishing stocks in the region. Two mitochondrial regions were examined (D-loop and COI) along…

Gene Flow0106 biological sciences0301 basic medicinePopulation geneticsPopulationZoologyPopulation geneticslcsh:MedicineDNA Mitochondrial010603 evolutionary biology01 natural sciencesMarine fish03 medical and health sciencesMediterranean seaGene FrequencyMediterranean SeaAnimals14. Life underwatereducationlcsh:ScienceAtlantic OceanAllelesPhylogenyIsolation by distanceCell NucleusPanmixiaeducation.field_of_studyMultidisciplinary[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]biologylcsh:RGenetic VariationBayes TheoremDentex dentexbiology.organism_classificationMitochondrial DNAMitochondriaPerciformesDentex dentex D-loop COI microsatellite loci Mediterranean Sea Atlantic Ocean.Polymerase chain reactionPhylogeographyPhylogeography[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal geneticsGenetics Population030104 developmental biologyHaplotypesGenetic structurelcsh:QMicrosatellite RepeatsPLoS ONE
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Is the population genetic structure of complex life cycle parasites determined by the geographic range of the most motile host?

2010

Due to their particular way of life, dispersal of parasites is often mediated by their host's biology. Dispersal distance is relevant for parasites because high degree of dispersal leads to high gene flow, which counters the rate of parasite local adaptation in the host populations. Parasites with complex life cycles need to exploit sequentially more than one host species to complete their life cycle. Most trematode parasites have such complex life cycles involving invertebrate and vertebrate hosts. The spatial scales of invertebrate and vertebrate host populations are often different, which may decrease the probability that the parasite cycles locally in the intermediate host population. W…

Gene Flow0106 biological sciencesMicrobiology (medical)Population DynamicsPopulationZoologyTrematode InfectionsBiologyPolymerase Chain Reaction010603 evolutionary biology01 natural sciencesMicrobiologyHost-Parasite InteractionsCharadriiformesFish Diseases03 medical and health sciencesGeneticsAnimalseducationMolecular BiologyEcology Evolution Behavior and SystematicsLymnaea030304 developmental biologyLocal adaptationIsolation by distanceLife Cycle Stages0303 health scienceseducation.field_of_studyPolymorphism GeneticBase SequenceGeographyBird DiseasesHost (biology)FishesIntermediate hostGenetic Variationbiology.organism_classificationObligate parasiteInfectious DiseasesBiological dispersalAnimal MigrationDNA IntergenicTrematodaTrematodaMicrosatellite RepeatsInfection, Genetics and Evolution
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Divergent Macroparasite Infections in Parapatric Swiss Lake-Stream Pairs of Threespine Stickleback (Gasterosteus aculeatus)

2015

Spatial heterogeneity in diversity and intensity of parasitism is a typical feature of most hostparasite interactions, but understanding of the evolutionary implications of such variation is limited. One possible outcome of infection heterogeneities is parasite-mediated divergent selection between host populations, ecotypes or species which may facilitate the process of ecological speciation. However, very few studies have described infections in populationpairs along the speciation continuum from low to moderate or high degree of genetic differentiation that would address the possibility of parasite-mediated divergent selection in the early stages of the speciation process. Here we provide…

Gene FlowGenetic SpeciationAllopatric speciationlcsh:MedicinePopulation geneticsGasterosteusParapatric speciationjärvetinfektiotEcological speciationHost-Parasite InteractionsFish DiseaseslakesAnimalsinfectionslcsh:ScienceEcosystemkolmipiikkiMultidisciplinarybiologylcsh:RSticklebackbiology.organism_classificationBiological EvolutionSmegmamorphaLakesGenetic SpeciationEvolutionary biologythreespine sticklebackta1181Macroparasite570 Life sciences; biologylcsh:QResearch ArticleMicrosatellite Repeats
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Morphology and genetics reveal an intriguing pattern of differentiation at a very small geographic scale in a bird species, the forest thrush Turdus …

2014

12 pages; International audience; Mobile organisms are expected to show population differentiation only over fairly large geographical distances. However, there is growing evidence of discrepancy between dispersal potential and realized gene flow. Here we report an intriguing pattern of differentiation at a very small spatial scale in the forest thrush (Turdus lherminieri), a bird species endemic to the Lesser Antilles. Analysis of 331 individuals from 17 sampling sites distributed over three islands revealed a clear morphological and genetic differentiation between these islands isolated by 40-50 km. More surprisingly, we found that the phenotypic divergence between the two geographic zone…

Gene FlowGenotypePopulationForestsBiologyDNA MitochondrialGene flowForest thrushEvolution MolecularSongbirdsGeneticsAnimalseducationGuadeloupeGenetics (clinical)IslandsmtDNA control regioneducation.field_of_studyHabitat fragmentationGeographyModels GeneticEcology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]Sequence Analysis DNA15. Life on landbiology.organism_classificationGenetics PopulationPhenotype[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]Spatial ecologyBiological dispersalMicrosatelliteOriginal ArticleMicrosatellite Repeats
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