Search results for "respiration."

showing 3 items of 533 documents

Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: Study protocol for a pilot randomized controlled trial, the PROT…

2018

Background Adding cyclic short sustained inflations (sigh) to assisted ventilation yields optimizes lung recruitment, decreases heterogeneity and reduces inspiratory effort in patients with acute hypoxemic respiratory failure (AHRF). These findings suggest that adding sigh to pressure support ventilation (PSV) might decrease the risk of lung injury, shorten weaning and improve clinical outcomes. Thus, we conceived a pilot trial to test the feasibility of adding sigh to PSV (the PROTECTION study). Methods PROTECTION is an international randomized controlled trial that will be conducted in 23 intensive care units (ICUs). Patients with AHRF who have been intubated from 24 h to 7 days and under…

procedurePressure supportTime Factorsgenetic structuresbreathingmedicine.medical_treatmentMedicine (miscellaneous)Pilot Projects[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractintensive care unitlaw.inventionPositive-Pressure RespirationStudy Protocol0302 clinical medicineMechanical ventilationRandomized controlled triallawtime factorClinical endpointpatient safetyMulticenter Studies as TopicPharmacology (medical)030212 general & internal medicinerandomized controlled trial (topic)Intervention study; Mechanical ventilation; Positive-pressure ventilation; Pressure support; Recruitment; Sigh; Ventilator-induced lung injury; Weaning; Feasibility Studies; Humans; Hypoxia; Intubation Intratracheal; Lung; Multicenter Studies as Topic; Pilot Projects; Positive-Pressure Respiration; Recovery of Function; Respiratory Insufficiency; Time Factors; Treatment Outcome; Randomized Controlled Trials as Topic; Medicine (miscellaneous); Pharmacology (medical)HypoxiaLungpathophysiologyendotracheal intubationRandomized Controlled Trials as TopicVentilator-induced lung injurylcsh:R5-920Intervention studyadultpilot studyfeasibility studytreatment outcome Feasibility Studie3. Good healthTreatment OutcomeAnesthesiapositive end expiratory pressureBreathingmulticenter study (topic)oxygenationRecruitmentlcsh:Medicine (General)Respiratory Insufficiencyrespiratory tract intubationcirculatory and respiratory physiologyHumanextubationPressure support ventilationWeaningLung injuryArticleSpontaneous breathing trialNO03 medical and health sciencesIntensive care[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]medicineIntubation IntratrachealHumanscontrolled studyPilot ProjectSightreatment failureMechanical ventilationhypoxemiapressure support ventilationtreatment durationbusiness.industrylung inflationrespiratory failureconvalescenceRecovery of Functionmajor clinical studymortalitywater acute respiratory failurehospital dischargeIntratracheal030228 respiratory systemrandomized controlled trialFeasibility StudiesbusinessPositive-pressure ventilationIntubationclinical protocol
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­Cardiac cycle and respiration phase affect responses to the conditioned stimulus in young adults trained in trace eyeblink conditioning

2022

Rhythms of breathing and heartbeat are linked to each other as well as to rhythms of the brain. Our recent studies suggest that presenting the conditioned stimulus during expiration or during the diastolic phase of the cardiac cycle facilitates neural processing of that stimulus and improves learning an eyeblink classical conditioning task. To date, it has not been examined whether utilizing information from both respiration and cardiac cycle phases simultaneously allows even more efficient modulation of learning. Here we studied whether the timing of the conditioned stimulus to different cardiorespiratory rhythm phase combinations affects learning trace eyeblink conditioning in healthy you…

sykelearningBlinkingoppiminenbreathingPhysiologyRespirationGeneral NeuroscienceConditioning Classicalherätevastesydämen sykeElectroencephalographykognitiiviset prosessitConditioning EyelidpsykofysiologiaYoung Adultevent-related potentialehdollistuminenhengitysHumansAgedheartbeat
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Rhythmic Memory Consolidation in the Hippocampus

2022

Functions of the brain and body are oscillatory in nature and organized according to a logarithmic scale. Brain oscillations and bodily functions such as respiration and heartbeat appear nested within each other and coupled together either based on phase or based on phase and amplitude. This facilitates communication in wide-spread neuronal networks and probably also between the body and the brain. It is a widely accepted view, that nested electrophysiological brain oscillations involving the neocortex, thalamus, and the hippocampus form the basis of memory consolidation. This applies especially to declarative memories, that is, memories of life events, for example. Here, we present our vie…

värähtelytbrain oscillationshengityselektrofysiologiahermoverkot (biologia)hippokampussleepelectrophysiologyneuronal circuitsrespirationuni (lepotila)muisti (kognitio)
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