Search results for "respiration"

showing 10 items of 538 documents

Independent right lung high frequency and left lung conventional ventilation in the management of severe air leak during ARDS

1995

Summary Pulmonary air leaks are one of the most common problems in patients with the adult respiratory distress syndrome, ARDS. We report what we believe to be the first case in which unilateral high-frequency ventilation combined with contralateral conventional positive pressure ventilation has been used successfully to manage severe air leak in an infant with ARDS.

MaleARDSFistulaAir leaklaw.inventionHigh-Frequency Jet VentilationPositive-Pressure RespirationlawHumansMedicineIn patientCushing SyndromeLungRespiratory Distress Syndrome NewbornLeft lungLungRespiratory distressbusiness.industryInfant NewbornInfantPneumothoraxPleural Diseasesmedicine.diseaseAnesthesiology and Pain Medicinemedicine.anatomical_structurePulmonary EmphysemaAnesthesiaPediatrics Perinatology and Child HealthVentilation (architecture)Bronchial FistulabusinessConventional ventilationPediatric Anesthesia
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Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries

2018

Background: To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS recruited into the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG-SAFE) study. Methods: This is a secondary analysis of LUNG-SAFE, an international, multicenter, prospective cohort study of patients receiving invasive or noninvasive ventilation in 50 countries spanning 5 continents. The study was carried out over 4 weeks consecutively in the winter of 2014, and 459 ICUs participated. We evaluated the clinical characteris…

MaleARDSInternationality[SDV]Life Sciences [q-bio]humanoslnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]traqueostomíaCritical Care and Intensive Care MedicineSeverity of Illness IndexCohort StudiesPropensity-matched analysi0302 clinical medicineTracheostomyestudios prospectivosEpidemiologyAcute respiratory distress syndrome (ARDS)030212 general & internal medicineProspective Studiespuntuación de propensión10. No inequalityProspective cohort studyestudios de cohortesmediana edadancianoRespiratory Distress SyndromerespiraciónRespirationlcsh:Medical emergencies. Critical care. Intensive care. First aidMiddle Aged3. Good healthIntensive Care UnitsCohortArtificialCritical IllneFemaleAcute respiratory distress syndrome (ARDS); ICU; Propensity-matched analysis; Tracheostomy; Ventilation; Aged; Cohort Studies; Critical Illness; Female; Humans; Intensive Care Units; Internationality; Male; Middle Aged; Propensity Score; Prospective Studies; Respiration Artificial; Respiratory Distress Syndrome Adult; Severity of Illness Index; TracheostomyCohort studyHumanAdultmedicine.medical_specialtyCritical IllnessIntensive Care UnitSocio-culturaleunidades de cuidados intensivosenfermedad críticaPropensity-matched analysis03 medical and health sciencesAcute respiratory distress syndrome (ARDS); ICU; Propensity-matched analysis; Tracheostomy; VentilationSeverity of illnessSettore MED/41 - ANESTESIOLOGIAmedicineHumansíndice de gravedad de la enfermedadPropensity ScoreAgedbusiness.industryResearchRespiratory Distress Syndrome Adultinternacionalidadlcsh:RC86-88.9medicine.diseaseR1Respiration ArtificialVentilationProspective Studie030228 respiratory systemPropensity score matchingEmergency medicineICUObservational studyCohort Studiebusiness
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Influence of PEEP on cerebral blood flow and cerebrovascular autoregulation in patients with acute respiratory distress syndrome.

2013

High levels of positive end-expiratory pressure (PEEP), as part of the treatment in patients with acute respiratory distress syndrome (ARDS), may prevent alveolar collapse and maintain oxygenation. PEEP potentially reduces cerebral venous return, increases intracranial blood volume, and may, therefore, affect cerebral blood flow (CBF) and cerebrovascular autoregulation (AR). This study investigates the effect of PEEP on CBF and AR in patients with respiratory failure.CBF velocity was measured using transcranial doppler and correlated with the invasive arterial blood pressure curve to calculate the index of AR Mx (Mx0.3 indicates impaired AR). Mx was measured at lower PEEP levels and after i…

MaleARDSmedicine.medical_specialtyCritical CareUltrasonography Doppler TranscranialBlood volumeBlood PressurePreoperative carePositive-Pressure RespirationOxygen ConsumptionInternal medicinePreoperative CaremedicineHomeostasisHumansHypnotics and SedativesIn patientCollapse (medical)AgedAged 80 and overRespiratory Distress SyndromeBlood Volumebusiness.industryOxygenationrespiratory systemMiddle Agedmedicine.diseaserespiratory tract diseasesOxygenAnesthesiology and Pain MedicineCerebral blood flowCerebrovascular CirculationCardiologySurgeryFemaleNeurology (clinical)medicine.symptombusinesstherapeuticsVenous return curvecirculatory and respiratory physiologyJournal of neurosurgical anesthesiology
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Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multice…

2019

Contains fulltext : 208648.pdf (Publisher’s version ) (Closed access) OBJECTIVES: To understand the impact of mild-moderate and severe acute kidney injury in patients with acute respiratory distress syndrome. DESIGN: Secondary analysis of the "Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure", an international prospective cohort study of patients with severe respiratory failure. SETTING: Four-hundred fifty-nine ICUs from 50 countries across five continents. SUBJECTS: Patients with a glomerular filtration rate greater than 60 mL/min/1.73 m prior to admission who fulfilled criteria of acute respiratory distress syndrome on day 1 and day 2 of acute …

MaleARDSmedicine.medical_treatmentComorbidityCritical Care and Intensive Care MedicineSeverity of Illness Indexchemistry.chemical_compound0302 clinical medicineacute kindey faliureRisk FactorsOdds Ratio80 and overHospital MortalityProspective StudiesAged 80 and overRespiratory Distress SyndromeRespirationAcute kidney injuryMiddle Agedacute kidney injury acute respiratory distress syndrome invasive mechanical ventilation mortality renal replacement therapyIntensive Care Unitsacute kidney injuryCreatinineArtificialFemaleGlomerular Filtration RateAdultinvasive mechanical ventilationrenal replacement therapy.medicine.medical_specialtySocio-culturaleRenal functionard03 medical and health sciencesInternal medicineSettore MED/41 - ANESTESIOLOGIASeverity of illnessmedicineHumansacute kidney injury acute respiratory distress syndromeRenal replacement therapyAgedCreatinineRenal replacement therapybusiness.industry030208 emergency & critical care medicineCarbon Dioxideacute respiratory distress syndromemedicine.diseaseRespiration Artificialmortalitylnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]030228 respiratory systemchemistryRespiratory failurebusinessRespiratory minute volume
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Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study

2018

Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initial…

MaleARDSmedicine.medical_treatmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]ARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS;Critical Care and Intensive Care Medicineassisted ventilation0302 clinical medicineRisk Factors030212 general & internal medicinerisk factor AdultTidal volumecomparative studyeducation.field_of_studyRespiratory Distress SyndromeMortality rateRemission Inductiontidal volumeARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS; Critical Care and Intensive Care MedicineARDS reassessmentartificial ventilationclinical trialimmunosuppressive treatmentadult respiratory distress syndromeMiddle AgedARDS SurvivalMonte Carlo methodmedicine.anatomical_structureclassificationpositive end expiratory pressureCardiologyDisease ProgressionSOFA scoredisease severityFemaleAdultmedicine.medical_specialtyPopulationdisease classificationArticleNO03 medical and health sciencesremissionlength of stayAnesthesiologyInternal medicinemedicinepneumoniaSequential Organ Failure Assessment ScoreHumanshumaneducationAgedMechanical ventilationhospital mortalityLungbusiness.industryRisk Factordisease associationRespiratory Distress Syndrome AdultPersisting ARDSmedicine.diseasemajor clinical studymortalityRespiration Artificialbreathing rate030228 respiratory systemdisease exacerbationBerlin criteria ARDSbusinessIntensive care medicine
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Immunocompromised patients with acute respiratory distress syndrome: Secondary analysis of the LUNG SAFE database

2018

Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiog…

MaleARDSmodelos logísticosDatabases Factualmedicine.medical_treatment[SDV]Life Sciences [q-bio]humanoslnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Kaplan-Meier EstimateCritical Care and Intensive Care MedicineAcute respiratory failureSeverity of Illness IndexCohort Studiesrandomized-trial0302 clinical medicineMechanical ventilationRisk Factorsestudios prospectivosEpidemiology80 and overicuMedicineProspective StudiesProspective cohort studyestudios de cohortesImmunodeficiencymediana edadestadísticasAged 80 and overRespiratory Distress Syndromeancianocritically-ill patientsRespirationresultado del tratamientorespiraciónStatisticslcsh:Medical emergencies. Critical care. Intensive care. First aidadultoMiddle Aged3. Good healthfailureIntensive Care UnitsTreatment OutcomeArtificialCohortprospective multicenterImmunocompromised patientsAcute respiratory failure; ARDS; Immunocompromised patients; Mechanical ventilation; Noninvasive ventilation; Critical Care and Intensive Care MedicineFemaleNoninvasive ventilationHumanestimación de Kaplan-MeierAdultmedicine.medical_specialtyLogistic ModelIntensive Care UnitSocio-culturaleunidades de cuidados intensivossurvivalStatistics NonparametricSepsisDatabases03 medical and health sciencesImmunocompromised HostInternal medicineImmunocompromised patientcancerfactores de riesgoHumansNonparametricíndice de gravedad de la enfermedadintensive-care-unitFactualAgedMechanical ventilationbusiness.industryResearchRisk FactorRespiratory Distress Syndrome Adult030208 emergency & critical care medicinelcsh:RC86-88.9medicine.diseaseRespiration ArtificialPneumoniaProspective StudieLogistic Models030228 respiratory systemmalignanciesARDShuésped inmunodeprimidoCohort StudiebusinessAcute respiratory failure; ARDS; Immunocompromised patients; Mechanical ventilation; Noninvasive ventilation; Adult; Aged; Aged 80 and over; Cohort Studies; Databases Factual; Female; Humans; Intensive Care Units; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Prospective Studies; Respiration Artificial; Respiratory Distress Syndrome Adult; Risk Factors; Severity of Illness Index; Statistics Nonparametric; Treatment Outcome; Immunocompromised Host
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Oral breathing and head posture

2006

Abstract Objective: To determine the head posture and cephalometric characteristics in oral breathing children. Materials and Methods: Lateral cephalograms taken in natural head posture of 35 oral breathing patients (OB) (mean age 8.8 ± 2.2 years SD; range 5–13 years) and of 35 patients with varied malocclusions and physiological breathing (PB) (mean age 9.7 ± 1.6 years SD; range 7–13 years) were examined. Results: A Student's t-test showed that an increase in angles NSL/OPT (P = .000), NSL/CVT (P = .001), FH/OPT (P = .000), FH/CVT (P = .005), and NSL/VER (P = .000); a decrease in the distance MGP-CV1p (P = .0001); and a decrease in the angles MGP/OP (P = .000) and OPT/ CVT (P = .036) were …

MaleAdolescentCephalometryPostureOrthodonticsMandibleNoseMaxillaMedicineHumansSella TurcicaChildOrthodonticsHead posturebusiness.industryRespiratory airwayOral breathingAirway ResistanceRespirationLateral cephalogramsHyoid boneHyoid BoneMean ageAnatomyMouth BreathingCraniometryChild PreschoolBreathingCervical VertebraeFemalebusinessHeadMalocclusion
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The Association of Self-Reported Birthweight with Lung Function and Respiratory Diseases: Results from a Multi-Centre, Multi-Case Control Study in It…

2022

Early life conditions are associated with lung function and the development of respiratory and non-respiratory illnesses. The relationship with birthweight (BW), however, is conflicting. We examined associations of self-reported BW with lung function and the development of respiratory and also non-respiratory diseases within the GEIRD (Gene–Environment Interaction in Respiratory Diseases) project, an Italian multi-centre, multi-case control study involving cases of COPD, asthma, allergic rhinitis and controls. Multinomial logistic regression was performed with case/control status as response variable; BW as main determinant; and adjusting for sex, age and smoking status. Of the 2287 p…

MaleAdultrespiratory healthadult health; birthweight; early life; lung volumes; respiratory diseases; respiratory healthrespiratory diseasesHealth Toxicology and Mutagenesisadult healthPublic Health Environmental and Occupational Healthrespiratory health.Settore MED/10 - Malattie Dell'Apparato RespiratorioRespiration Disordersrespiratory diseaseItalybirthweightCase-Control StudiesHumansBirth Weightearly lifeFemaleSelf Reportlung volumelung volumesLungInternational Journal of Environmental Research and Public Health
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Nifedipine improves blood flow and oxygen supply, but not steady-state oxygenation of tumours in perfusion pressure-controlled isolated limb perfusio…

2002

Isolated limb perfusion allows the direct application of therapeutic agents to a tumour-bearing extremity. The present study investigated whether the dihydropyridine-type Ca2+-channel blocker nifedipine could improve blood flow and oxygenation status of experimental tumours during isolated limb perfusion. Perfusion was performed by cannulation of the femoral artery and vein in rats bearing DS-sarcoma on the hind foot dorsum. Perfusion rate was adjusted to maintain a perfusion pressure of 100–140 mmHg throughout the experiment. Following equilibration, nifedipine was continuously infused for 30 min (8.3 μg min−1 kg−1 BW). During constant-pressure isolated limb perfusion, nifedipine can signi…

MaleCancer ResearchNifedipinecalcium channel blockerCell RespirationHemodynamicsFemoral arteryMicrocirculationRats Sprague-DawleyNifedipinemedicine.arterymedicineLaser-Doppler FlowmetryAnimalsExperimental TherapeuticsInfusions Intravenoustumour vascular resistancebusiness.industrytumour perfusionBlood flowOxygenationHypoxia (medical)Calcium Channel BlockersRatsOxygenOncologyRegional Blood FlowAnesthesiaChemotherapy Cancer Regional PerfusionSarcoma Experimentalmedicine.symptombusinessPerfusiontumour oxygenationmedicine.drugisolated limb perfusionBritish journal of cancer
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Propofol sedation reduces diaphragm activity in spontaneously breathing patients: ultrasound assessment.

2017

BACKGROUND: The diaphragm is the most important respiratory muscle in humans, and the close relationship between inspired volume and diaphragmatic movement in normal subjects has led to investigations into diaphragmatic activity using ultrasound, during spontaneous breathing and sedative drug infusion. METHODS: A total of 36 consecutive patients undergoing diagnostic procedures under deep propofol sedation were studied. Ultrasound measurements included the following: diaphragmatic thickening end-inspiration (TEI) and endexpiration (TEE). Diaphragmatic thickening fraction (DTF) was calculated from [(TEI TEE) / TEE] at various time points (at T0 basal; at T1 during propofol infusion; at T2 aw…

MaleDeep sedation; Diaphragm; Propofol; Ultrasonography; Anesthesiology and Pain MedicineRespiratory rateSedationdeep sedation; diaphragm; propofol; ultrasonographyDiaphragmHypnotics and SedativeDiaphragmatic breathing03 medical and health sciences0302 clinical medicine030202 anesthesiologySettore MED/41 - ANESTESIOLOGIARespiratory muscleMedicineHumansHypnotics and SedativesProspective StudiesPropofolUltrasonographybusiness.industryRespirationUltrasound030208 emergency & critical care medicineMiddle AgedDiaphragm (structural system)Prospective StudieAnesthesiology and Pain MedicineAnesthesiaBreathingFemalemedicine.symptomDeep SedationbusinessPropofolmedicine.drugHumanMinerva anestesiologica
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