Search results for "retractions"

Retracted papers on SARS-CoV-2 and COVID-19

2021

Internal inverse limits and retractions

2015

We establish equivalences between compacta that admit a sequence of retractions that converge uniformly to the identity map and compacta that are inverse limits on subcompacta with retractions for bonding maps. We give partial answers to questions of Charatonik and Prajs, and of Krasinkiewicz. Our results are related to and use results from another paper of the authors \cite{mp}.

Lipase maturation factor 1 is required for endothelial lipase activity

2011

Lipase maturation factor 1 (Lmf1) is an endoplasmic reticulum (ER) membrane protein involved in the posttranslational folding and/or assembly of lipoprotein lipase (LPL) and hepatic lipase (HL) into active enzymes. Mutations in Lmf1 are associated with diminished LPL and HL activities ("combined lipase deficiency") and result in severe hypertriglyceridemia in mice as well as in human subjects. Here, we investigate whether endothelial lipase (EL) also requires Lmf1 to attain enzymatic activity. We demonstrate that cells harboring a (cld) loss-of-function mutation in the Lmf1 gene are unable to generate active EL, but they regain this capacity after reconstitution with the Lmf1 wild type. Fur…