Search results for "retrospective analysi"
showing 10 items of 87 documents
A retrospective analysis of immunohistochemical determined IRF4 (interferon regulating factor 4) expression in a consecutive cohort of 114 ovarian ca…
2018
The role of second and third line tyrosine kinase inhibitor monotherapy in EGFR wild-type (and unknown mutational status) advanced non-small-cell lun…
2015
Dentoalveolar changes in adults promoted by the use of auxiliary expansion arch: A CBCT study
2019
Background The objective of this study was to evaluate the dentoalveolar effects and the changes of buccal cortical bone in the posterior area after expansion obtained with TMA auxiliary expansion arch in adult patients. Material and Methods A retrospective analysis of CT scans of 13 patients (6 male, 7 female) treated at a private clinic, taken immediately before and after the use of an auxiliary expansion archwire, was performed. Mean age at installation of TMA auxiliary expansion arch was 29.23 years (s.d.=9.13) and the mean age when the auxiliary arch was removed was 29.52 years (s.d.=9.16). Mean time of the use of the TMA auxiliary expansion arch was 0.29 years (s.d.=0.09). The patient…
Calidad de la farmacoterapia y seguridad de los pacientes en hemodiálisis tratados con estimulantes eritropoyéticos
2008
Objective: To assess an interdisciplinary programme for the improvement of pharmacotherapy quality and patient safety in patients with chronic renal disease who are treated with erythropoiesis-stimulating agents. Method: Observational, longitudinal study. Retrospective analysis (period A) and prospective analysis (period B) following implementation of the programme for haemoglobin values and monthly erythropoiesis- stimulating agent dosage. The proportion of patients with haemoglobin values within the target range (10-5-12.5 g/dl) and those with values above the safety limit (≥ 12.5g/dl) were compared every four months and the average percentage of time with haemoglobin values within the ta…
Impact of 70 years urban growth associated with heavy metal pollution
2014
Historical trends in trace element deposition were analyzed using herbaria specimens. We determined Al, Fe, Mg, Mn, Ca, Na, P, K, S, As, Cd, Cr, Cu, Ni, Pb and Zn contents in leaves of eight specimens collected in 1941. To assess changes, we collected the same plants from a botanical garden in 2012. The concentrations of major elements showed large species variability. However, temporal trends were predominately detected for heavy metals. The Cd, Ni and Cr contents in the 2012 leaves were 10, 13 and 16 times higher, respectively, than in 1941. Urban activities have substantially raised the levels of these metals in urban atmospheres due to changes in human activities over 70 years of urban …
Exceptional LAS Requests in Eurotransplant: Analysis of an 8-year Effort to Improve Lung Allocation for Precarious Patients
2020
PURPOSE: Following introduction of the lung allocation score (LAS) in 2011, Eurotransplant member centers can apply for an exceptional LAS (eLAS) if the calculated LAS insufficiently reflects the perceived transplant benefit for a patient, specifically in case of primary pulmonary hypertension group 1 and 4; combined lung+non-renal transplantation; rare diseases; or extracorporeal support. Each eLAS proposal is evaluated by a LAS Review Board, consisting of ≥3 lung transplant experts, which subsequently declines or approves the eLAS request in consensus of ≥3 votes. In case of a lower than accepted score, predefined business rules to assign LAS percentiles are used. METHODS: A retrospective…
What drives inhaler prescription for asthma patients? Results from a real-life retrospective analysis
2020
Abstract Background The choice of inhaler device for asthma patients depends upon multiple attributes. We investigated factors that may drive general practitioners (GPs) and respiratory specialists in the prescription of inhaler devices for asthma patients who initiated inhalation therapy. Methods We retrospectively analysed prescriptions by GPs and respiratory specialists to asthma patients commencing inhaled corticosteroid/long-acting β2-agonist combination therapy available as both pressurised metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs). Patient characteristics were compared by device and multivariate analysis was used to model the likelihood of receiving a pMDI as oppos…
Semi-ResMass Study: Residual masses after salvage chemotherapy in men with pure seminoma—A multicenter retrospective analysis.
2020
420 Background: Only scarce data exist on the management of residual masses in men who have received two lines of chemotherapy for advanced seminoma. Due to the lack of data, the role of PET scanning, surgery and other additional treatments is controversial in these men. Methods: Data from men with pure seminoma and residual masses after salvage chemotherapy were retrospectively collected from 10 high-volume centers in 3 European countries. We analyzed the clinical management of residual masses (imaging, surgery, pathological data, and additional treatment modalities) and long-term outcomes. Residual mass was defined as a lesion of ≥1 cm after two lines of platin-based chemotherapy. Result…
Ethics appraisal procedure in 79,670 Marie Skłodowska-Curie proposals from the entire European HORIZON 2020 research and innovation program (2014–202…
2021
Introduction Horizon 2020 was the most significant EU Research and Innovation programme ever implemented and included the Marie Skłodowska-Curie Actions (MSCA). Proposals submitted to the MSCA actions awere subject to the Ethics Appraisal Procedure. In this work we explored the ethics appraisal procedure in MSCA H2020. Methods Using a retrospective analysis of pooled anonymized data, we explored the ethics appraisal procedure on proposals submitted to Marie Skłodowska-Curie Actions (MSCA) during the entire Horizon 2020 program period (N = 79,670). Results Our results showed that one of the most frequently identified ethics categories was Data protection. We also detected slight differences…
A retrospective analysis of oral and maxillofacial lesions in children and adolescents reported in two different services.
2021
Background Most epidemiological studies involving oral and maxillofacial lesions assess only data from histopathological analysis. This may lead to a poor notification of diseases whose diagnosis is predominantly clinical. Aim: To evaluate and to compare the frequency of oral and maxillofacial lesions in children and adolescents in two different types of services: Oral Medicine clinic service and laboratory service. Material and methods The records of patients ≤ 19 years attending the Oral Medicine clinic service and records from the laboratory service in Oral and Maxillofacial Pathology of the Dental School of a university were analyzed. Results 828 records from the Oral Medicine clinic se…