Search results for "rex"
showing 10 items of 701 documents
Solar Neutrino Observables Sensitive to Matter Effects
2010
We discuss constraints on the coefficient A_{MSW} which is introduced to simulate the effect of weaker or stronger matter potential for electron neutrinos with the current and future solar neutrino data. The currently available solar neutrino data leads to a bound A_{MSW} = 1.47^{-0.42}_{+0.54} (^{-0.82}_{+1.88}) at 1\sigma (3\sigma) CL, which is consistent with the Standard Model prediction A_{MSW} = 1. For weaker matter potential (A_{MSW} 1), the bound is milder and is dominated by the day-night asymmetry of ^8B neutrino flux recently observed by Super-Kamiokande. Among the list of observable of ongoing and future solar neutrino experiments, we find that (1) an improved precision of the d…
Robust signatures of solar neutrino oscillation solutions
2001
With the goal of identifying signatures that select specific neutrino oscillation parameters, we test the robustness of global oscillation solutions that fit all the available solar and reactor experimental data. We use three global analysis strategies previously applied by different authors and also determine the sensitivity of the oscillation solutions to the critical nuclear fusion cross section, S_{17}(0), for the production of 8B. The favored solutions are LMA, LOW, and VAC in order of g.o.f. The neutral current to charged current ratio for SNO is predicted to be 3.5 +- 0.6 (1 sigma), which is separated from the no-oscillation value of 1.0 by much more than the expected experimental er…
Updating neutrino magnetic moment constraints
2016
20 pages.- 4 figures.- Addendum on the limit from the Borexino data
If sterile neutrinos exist, how can one determine the total solar neutrino fluxes?
2002
The 8B solar neutrino flux inferred from a global analysis of solar neutrino experiments is within 11% (1 sigma) of the predicted standard solar model value if only active neutrinos exist, but could be as large as 1.7 times the standard prediction if sterile neutrinos exist. We show that the total 8B neutrino flux (active plus sterile neutrinos) can be determined experimentally to about 10% (1 sigma) by combining charged current measurements made with the KamLAND reactor experiment and with the SNO CC solar neutrino experiment, provided the LMA neutrino oscillation solution is correct and the simulated performance of KamLAND is valid. Including also SNO NC data, the sterile component of the…
Measuring the14C content in liquid scintillators
2016
We are going to perform a series of measurements where the 14C/12 C ratio will be measured from several liquid scintillator samples with a dedicated setup. The setup is designed with the aim of measuring ratios smaller than 10-18. Measurements take place in two underground laboratories: in the Baksan Neutrino Observatory, Russia and in the Pyhasalmi mine, Finland. In Baksan the measurements started in 2015 and in Pyhasalmi they start in the beginning of 2015. In order to fully understand the operation of the setup and its background contributions a development of simulation packages has also been started. Low-energy neutrino detection with a liquid scintillator requires that the intrinsic 1…
Low-energy (anti)neutrino physics with Borexino: Neutrinos from the primary proton-proton fusion process in the Sun
2014
The Sun is fueled by a series of nuclear reactions that produce the energy that makes it shine. The primary reaction is the fusion of two protons into a deuteron, a positron and a neutrino. These neutrinos constitute the vast majority of neutrinos reaching Earth, providing us with key information about what goes on at the core of our star. Several experiments have now confirmed the observation of neutrino oscillations by detecting neutrinos from secondary nuclear processes in the Sun; this is the first direct spectral measurement of the neutrinos from the keystone proton-proton fusion. This observation is a crucial step towards the completion of the spectroscopy of pp-chain neutrinos, as we…
Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review
2017
Marco Solmi,1,2 Andrea Murru,3 Isabella Pacchiarotti,3 Juan Undurraga,4,5 Nicola Veronese,2,6 Michele Fornaro,7,8 Brendon Stubbs,2,9–11 Francesco Monaco,2 Eduard Vieta,3 Mary V Seeman,12 Christoph U Correll,13,14 André F Carvalho2,15 1Neuroscience Department, University of Padua, 2Institute for Clinical Research and Education in Medicine, Padua, Italy; 3Bipolar Disorders Unit, Institute of Neuroscience, Hospital Clínic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain; 4Department of Psychiatry, Faculty of Medicine, Clínica Alemana Universidad del Desarrollo, 5Early Intervention Program, J. Horwitz Psychiatric Institute, Santiago, Chile; 6Na…
Hypothalamus-olfactory system crosstalk: orexin a immunostaining in mice
2012
It is well known that olfaction influences food intake, and conversely, that an individual’s nutritional status modulates olfactory sensitivity. However, what is still poorly understood is the neuronal correlate of this relationship, as well as the connections between the olfactory bulb and the hypothalamus. The goal of this report is to analyze the relationship between the olfactory bulb and hypothalamus, focusing on orexin A immunostaining, a hypothalamic neuropeptide that is thought to play a role in states of sleep/wakefulness. Interestingly, orexin A has also been described as a food intake stimulator. Such an effect may be due in part to the stimulation of the olfactory bulbar pathway…
Conventional induction and post-remission therapy in APL: have we arrived?
2014
Since the introduction of all-trans-retinoic acid, the use of this molecularly targeted treatment in combination with anthracycline-based chemotherapy has completely changed the prognosis of acute promyelocytic leukemia (APL) turning it into the most curable acute myeloid leukemia. Also, the use of risk-adapted protocols has optimized the drug combination and the most appropriate dose intensity for each subset of patients classified according to both risk of relapse and vulnerability to drug toxicity. Recent developments have included the investigation of the role of arsenic trioxide (ATO) as front-line treatment after its success in relapsed APL, both to minimize or even omit the use of cy…
Whole-brain radiotherapy or autologous stem-cell transplantation as consolidation strategies after high-dose methotrexate-based chemoimmunotherapy in…
2017
Background The International Extranodal Lymphoma Study Group-32 (IELSG32) trial is an international randomised phase 2 study that addresses two key clinical questions in the treatment of patients with newly diagnosed primary CNS lymphoma. Results of the first randomisation have demonstrated that methotrexate, cytarabine, thiotepa, and rituximab (called the MATRix regimen) is the induction combination associated with significantly better outcome compared with the other induction combinations tested. Here, we report the results of the second randomisation that addresses the efficacy of myeloablative chemotherapy supported by autologous stem-cell transplantation (ASCT), as an alternative to wh…