Search results for "rex"
showing 10 items of 701 documents
Interstitial lung disease induced by drugs and radiation.
2004
An ever-increasing number of drugs can reproduce variegated patterns of naturally occurring interstitial lung disease (ILD), including most forms of interstitial pneumonias, alveolar involvement and, rarely, vasculitis. Drugs in one therapeutic class may collectively produce the same pattern of involvement. A few drugs can produce more than one pattern of ILD. The diagnosis of drug-induced ILD (DI-ILD) essentially rests on the temporal association between exposure to the drug and the development of pulmonary infiltrates. The histopathological features of DI-ILD are generally consistent, rather than suggestive or specific to the drug etiology. Thus, the diagnosis of DI-ILD is mainly made by …
Phase II study of pemetrexed and cisplatin plus cetuximab followed by pemetrexed and cetuximab maintenance therapy in patients with advanced nonsquam…
2013
Abstract Objectives The aim was to determine if combined pemetrexed, cisplatin, and cetuximab was efficacious and safe as first-line treatment in advanced nonsquamous non-small cell lung cancer (NSCLC). Patients and methods In this single-arm, multicenter clinical trial, patients with Stage IIIB/IV nonsquamous NSCLC received first-line therapy consisting of pemetrexed (500mg/m 2 ) and cisplatin (75mg/m 2 ) on Day 1 (21-day cycles) plus weekly cetuximab (400mg/m 2 loading dose, then 250mg/m 2 ) for 4–6 cycles. Non-progressing patients received maintenance therapy consisting of pemetrexed and cetuximab as above until disease progression. All patients received vitamin supplementation, dexameth…
A randomized phase II study of pemetrexed in combination with cisplatin or carboplatin as first-line therapy for patients with locally advanced or me…
2013
Abstract Background Pemetrexed plus cisplatin was approved for first-line treatment of non–small-cell lung cancer (NSCLC) in patients with nonsquamous histology after initiation of this study. This phase II study evaluated pemetrexed plus cisplatin and pemetrexed plus carboplatin as first-line treatments for stage IIIB/IV NSCLC. Patients and Methods The patients were randomized (1:1) to 2 parallel arms: pemetrexed (500 mg/m2) plus cisplatin (75 mg/m2) or pemetrexed (500 mg/m2) plus carboplatin (area under the curve 6) day 1 every 3 weeks (maximum, 6 cycles). Progression-free survival (PFS) was the primary objective; secondary objectives included overall survival (OS), 1-year survival, and s…
ON A QUESTION OF BEIDLEMAN AND ROBINSON
2002
[EN] In [J. C. Beidleman, D. J. S. Robinson, J. Algebra 1997, 191, 686--703, Theorem A], Beidleman and Robinson proved that if a group satisfies the permutizer condition, it is soluble, its chief factors have order a prime number or 4 and G induces the full group of automorphisms in the chief factors of order 4. In this paper, we show that the converse of this theorem is false by showing some counterexamples. We also find some sufficient conditions for a group satisfying the converse of that theorem to satisfy the permutizer condition.
A note on finite determinacy for corank 2 map germs from surfaces to 3-space
2008
AbstractWe study properties of finitely determined corank 2 quasihomogeneous map germs f:($\C^2$, 0) → ($\C^3$, 0). Examples and counter examples of such map germs are presented.
On the quasi-isometric and bi-Lipschitz classification of 3D Riemannian Lie groups.
2021
AbstractThis note is concerned with the geometric classification of connected Lie groups of dimension three or less, endowed with left-invariant Riemannian metrics. On the one hand, assembling results from the literature, we give a review of the complete classification of such groups up to quasi-isometries and we compare the quasi-isometric classification with the bi-Lipschitz classification. On the other hand, we study the problem whether two quasi-isometrically equivalent Lie groups may be made isometric if equipped with suitable left-invariant Riemannian metrics. We show that this is the case for three-dimensional simply connected groups, but it is not true in general for multiply connec…
Hitchhiker's guide to the fractional Sobolev spaces
2012
AbstractThis paper deals with the fractional Sobolev spaces Ws,p. We analyze the relations among some of their possible definitions and their role in the trace theory. We prove continuous and compact embeddings, investigating the problem of the extension domains and other regularity results.Most of the results we present here are probably well known to the experts, but we believe that our proofs are original and we do not make use of any interpolation techniques nor pass through the theory of Besov spaces. We also present some counterexamples in non-Lipschitz domains.
Orbit spaces of Small Tori
2003
Consider an algebraic torus of small dimension acting on an open subset of ℂn, or more generally on a quasiaffine variety such that a separated orbit space exists. We discuss under which conditions this orbit space is quasiprojective. One of our counterexamples provides a toric variety with enough effective invariant Cartier divisors that is not embeddable into a smooth toric variety.
Multifunctions determined by integrable functions
2019
Integral properties of multifunctions determined by vector valued functions are presented. Such multifunctions quite often serve as examples and counterexamples. In particular it can be observed that the properties of being integrable in the sense of Bochner, McShane or Birkhoff can be transferred to the generated multifunction while Henstock integrability does not guarantee it.
Nowhere differentiable intrinsic Lipschitz graphs
2021
We construct intrinsic Lipschitz graphs in Carnot groups with the property that, at every point, there exist infinitely many different blow-up limits, none of which is a homogeneous subgroup. This provides counterexamples to a Rademacher theorem for intrinsic Lipschitz graphs.