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showing 10 items of 1985 documents

Right ventricular collagen type III and IV gene expression increases during early phases of endurance training in hypobaric hypoxic condition

1997

The objective of this study was to examine the effects of prolonged exposure to hypobaric hypoxic condition, physical training and their combination on collagen type I, III and IV gene expression in the ventricles and atria of rat heart. Male rats were assigned to four groups: normobaric sedentary (NS) and trained (NT), and hypobaric sedentary (HS) and trained (HT). Exposure to and treadmill running training in hypobaric condition were carried out in a hypobaric chamber (770–740 mbar, 2250–2550 m). Experimental periods were 10, 21 and 56 days; the groups of 91 days served as recovery groups from experimental settings of 56 days. Exposure to hypobaric condition as such and in combination wit…

MaleAtmosphere Exposure Chambersmedicine.medical_specialtyPhysiologyHeart VentriclesProcollagen-Proline DioxygenaseGene ExpressionCardiomegalyBiologyLeft ventricular hypertrophyCollagen Type IIIEndurance trainingRight ventricular hypertrophyPhysical Conditioning AnimalPhysiology (medical)Internal medicineGene expressionmedicineAnimalsHeart AtriaRNA MessengerRats WistarHypoxiaCardiac muscleBlotting Northernmedicine.diseaseRatsHydroxyprolineAtmospheric PressureEndocrinologymedicine.anatomical_structureMrna levelHypobaric chamberPhysical EnduranceCollagenCardiology and Cardiovascular MedicineBasic Research in Cardiology
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A Tunable Digital Ishihara Plate for Pre-School Aged Children

2016

Colors play a fundamental role for children, both in the everyday life and in education. They recognize the surrounding world, and play games making a large use of colors. They learn letters and numbers by means of colors. As a consequence, early diagnosis of color blindness is an crucial to support an individual affected by this visual perception alteration at the initial phase of his/her life. The diagnosis of red-green color deficiencies (protanopia or deuteranopia) is commonly accomplished by means of the Ishihara test, which consists of plates showing dots with different sizes where some of them compose numbers within a gamut of colors while the ones composing the background have diffe…

MaleBrightnessColor histogramComputer scienceColor balanceColor Vision Defects050105 experimental psychology03 medical and health sciences0302 clinical medicineGamutHumansIshihara color blindness dyschromatopsia web application0501 psychology and cognitive sciencesComputer visionChromatic scaleSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniInternetColor Perception Testsbusiness.industryBinary image05 social sciencesColor quantizationWeb colorsColor modelChild PreschoolCalibration030221 ophthalmology & optometryFemaleArtificial intelligencebusinessSoftware
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An adapted optical flow algorithm for robust quantification of cardiac wall motion from standard cine-MR examinations

2012

International audience; This paper presents a method for local myocardial motion estimation from a conventional steady-state free precession cine-MRI sequence using a modified phase-based optical flow (OF) technique. Initially, the technique was tested on synthetic images to evaluate its robustness with regards to Rician noise and to brightness variations. The method was then applied to cardiac images acquired on 11 healthy subjects. Myocardial velocity is measured in centimeter per second in each studied pixel and visualized as colored vectors superimposed on MRI images. The estimated phase-based OF results were compared with a reference OF method and gave similar results on synthetic imag…

MaleBrightnessPhysics::Medical Physics[INFO.INFO-IM] Computer Science [cs]/Medical Imaging02 engineering and technology030218 nuclear medicine & medical imagingmotion estimation0302 clinical medicineCine-MRI0202 electrical engineering electronic engineering information engineeringImage Processing Computer-AssistedComputer visionMESH : FemaleOptical filterMESH : AlgorithmsMathematicsMESH: Middle Aged[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingGeneral MedicineMESH: Magnetic Resonance Imaging CineMiddle AgedMESH : AdultMESH : Magnetic Resonance Imaging CineMESH: Image Processing Computer-AssistedComputer Science Applicationscardiovascular system020201 artificial intelligence & image processingFemaleAlgorithmsMESH : Image Processing Computer-AssistedBiotechnologyAdultMESH : MaleOptical flowMagnetic Resonance Imaging CineImage processingMESH: Algorithmsheartoptical flow03 medical and health sciencesMESH : HeartRobustness (computer science)Motion estimation[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology[INFO.INFO-IM]Computer Science [cs]/Medical ImagingHumansMESH : Middle AgedElectrical and Electronic EngineeringCentimeterMESH: HumansPixelbusiness.industryMESH : HumansMESH: AdultMESH: MaleMESH: HeartArtificial intelligencebusinessMESH: Female[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Modeling Right Ventricle Failure After Continuous Flow Left Ventricular Assist Device: A Biventricular Finite-Element and Lumped-Parameter Analysis

2017

The risk of right ventricle (RV) failure remains a major contraindication for continuous-flow left ventricular assist device (CF-LVAD) implantation in patients with heart failure. It is therefore critical to identify the patients who will benefit from early intervention to avoid adverse outcomes. We sought to advance the computational modeling description of the mechanisms underlying RV failure in LVAD-supported patients. RV failure was studied by computational modeling of hemodynamic and cardiac mechanics using lumped-parameter and biventricular finite element (FE) analysis. Findings were validated by comparison of bi-dimensional speckle-tracking echocardiographic strain assessment of the …

MaleCardiac CatheterizationCardiac outputVentricular Dysfunction Rightmedicine.medical_treatmentHemodynamicsSpeckle tracking echocardiography02 engineering and technology030204 cardiovascular system & hematologySeverity of Illness IndexRight ventricular failure Left ventricular assist device Speckle-tracking echocardiography Lumped-parameter Finite-element analysis.Ventricular Function LeftVentricular Dysfunction Left0302 clinical medicineRisk FactorsMedicineModels CardiovascularMiddle AgedTreatment Outcomemedicine.anatomical_structureEchocardiographyCardiologyFemaleCardiology and Cardiovascular MedicineAdultmedicine.medical_specialtyFinite Element Analysis0206 medical engineeringBiomedical EngineeringProsthesis DesignProsthesis Implantation03 medical and health sciencesInternal medicineSettore ING-IND/12 - Misure Meccaniche E TermicheHumansComputer SimulationInterventricular septumContraindicationRetrospective StudiesHeart Failurebusiness.industryHemodynamicsmedicine.disease020601 biomedical engineeringVentricleVentricular assist deviceHeart failureVentricular Function RightHeart-Assist DevicesbusinessCardiovascular Engineering and Technology
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12‐Month outcomes of transcatheter tricuspid valve repair with the PASCAL system for severe tricuspid regurgitation

2021

Objectives We investigated the durability of tricuspid regurgitation (TR) reduction and the clinical outcomes through 12 months after transcatheter tricuspid valve repair (TTVr) with the PASCAL Transcatheter Valve Repair System. Background TTVr has rapidly developed and demonstrated favorable acute outcomes, but longer follow-up data are needed. Methods Overall, 30 patients (age 77 ± 6 years; 57% female) received PASCAL implantation from September 2017 to May 2019 and completed a clinical follow-up at 12 months. Results The TR etiology was functional in 25 patients (83%), degenerative in three (10%), and mixed in two (7%). All patients had TR severe or greater (massive or torrential in 80%)…

MaleCardiac Catheterizationmedicine.medical_specialtyTime FactorsRegurgitation (circulation)030204 cardiovascular system & hematologytranscatheter tricuspid valve intervention PASCAL 12-month outcomes severe tricuspid regurgitation right-sided heart failure03 medical and health sciences0302 clinical medicinemedicineHumansEndocarditisRadiology Nuclear Medicine and imagingddc:610030212 general & internal medicineTRICUSPID VALVE REPAIRStrokeSurvival rateAgedAged 80 and overHeart Valve Prosthesis Implantationbusiness.industryPascal (unit)General Medicinemedicine.diseaseTricuspid Valve InsufficiencySurgeryTreatment OutcomeHeart failureEtiologyFemaleTricuspid ValveCardiology and Cardiovascular MedicinebusinessCatheterization and Cardiovascular Interventions
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Value of Echocardiographic Right Ventricular and Pulmonary Pressure Assessment in Predicting Transcatheter Tricuspid Repair Outcome

2020

The aim of this study was to assess the value of echocardiographic right ventricular (RV) and systolic pulmonary artery pressure (sPAP) assessment in predicting transcatheter tricuspid edge-to-edge valve repair (TTVR) outcome.RV dysfunction and pulmonary hypertension are associated with poor prognosis and are systematically sought during tricuspid regurgitation evaluation. The value of echocardiographic assessment in predicting TTVR outcome is unknown.Data were taken from the TriValve (Transcatheter Tricuspid Valve Therapies) registry, which includes patients undergoing TTVR at 14 European and North American centers. The primary outcome was 1-year survival free from hospitalization for hear…

MaleCardiac Catheterizationmedicine.medical_specialtyTime FactorsRegurgitation (circulation)Pulmonary Artery030204 cardiovascular system & hematologySeverity of Illness Index03 medical and health sciences0302 clinical medicinePrimary outcomePredictive Value of TestsInternal medicinemedicine.arteryVentricular PressureHumansMedicineArterial PressureProspective StudiesRegistries030212 general & internal medicineAgedAged 80 and overHeart FailureHospital readmissionTricuspid valvebusiness.industryRecovery of FunctionMiddle Agedmedicine.diseasePulmonary hypertensionTricuspid Valve Insufficiency3. Good healthPulmonary pressureEuropeTreatment Outcomemedicine.anatomical_structureEchocardiographyHeart failureNorth AmericaPulmonary arteryDisease ProgressionVentricular Function RightCardiologyFemaleCardiology and Cardiovascular MedicinebusinessJACC: Cardiovascular Interventions
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Multivariate analysis on complications of central venous access devices in children with cancer and severe disease influenced by catheter tip positio…

2019

Abstract Context Reliable long-term central venous access device (CVAD) is essential for the management of pediatric patients with cancer or chronic diseases. However, there is no general consensus for optimal catheter tip location and vessel insertion site in children. Objective This single center study analyzes the risk of complications associated with long-term upper body CVAD and evaluates them with respect to catheter tip location as well as vessel insertion site. Design Pediatric patients who received long-term upper body CVAD from January 2008 through April 2017 and underwent radiographic documentation of the tip location were retrospectively included in the study. Data on demographi…

MaleCatheterization Central Venousmedicine.medical_specialtyAdolescentmedicine.medical_treatmentContext (language use)03 medical and health sciencesPostoperative Complications0302 clinical medicineMetabolic DiseasesNeoplasms030225 pediatricsOcclusionmedicineHumansChildRetrospective StudiesBronchusbusiness.industryInfant NewbornInfantPrognosisHematologic DiseasesPediatric cancerSurgeryCathetermedicine.anatomical_structureImmune System DiseasesOncologyChild Preschool030220 oncology & carcinogenesisRight Main BronchusFemaleSurgeryComplicationbusinessCentral venous catheterFollow-Up StudiesSurgical Oncology
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Prismatic adaptation effects on spatial representation of time in neglect patients

2011

Abstract Processing of temporal information may require the use of spatial attention to represent time along a mental time line. We used prismatic adaptation (PA) to explore the contribution of spatial attention to the spatial representation of time in right brain damaged patients with and without neglect of left space and in age-matched healthy controls. Right brain damaged patients presented time underestimation deficits, that were significantly greater in patients with neglect than in patients without neglect. PA inducing leftward attentional deviation reduced time underestimation deficit in patients with neglect. The results support the hypothesis that a right hemispheric network has a …

MaleCognitive Neurosciencemedia_common.quotation_subjectTemporal deficitsExperimental and Cognitive PsychologyAdaptation (eye)Neuropsychological TestsFunctional LateralityLateralization of brain functionriabilitazioneNeglectPerceptual DisordersHumansAttentionIn patientSpatial representationRight hemispherePrismatic adaptationTemporal informationAgedmedia_commonAged 80 and overSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaneglectictuSpatial attentionMiddle AgedSpatial representation of timeTime perceptionAdaptation PhysiologicalNeuropsychology and Physiological PsychologySpace PerceptionTMSTime PerceptionFemalePsychologyCognitive psychologyCortex
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Impact of conversion from laparoscopy to open surgery in patients with right colon cancer

2019

Conversion to open surgery is reported in up to 20 per cent of laparoscopic colectomies for cancer. This study aims to compare postoperative outcomes and survival between converted and successful laparoscopic right colectomy for cancer. Records of patients who underwent laparoscopic right colectomy for cancer between 2005 and 2015 were retrieved from the CLermontFerrand Ircad Mondor Hopital European Tours (CLIMHET) database. Perioperative, postoperative, and survival outcomes were evaluated. Multivariate analysis was performed to identify predictive factors for conversion. Overall, 445 patients underwent a successfully completed laparoscopic right colectomy and 28 (5.9%) were converted to …

MaleColectomiesmedicine.medical_specialtyColorectal cancermedicine.medical_treatmentOperative TimeDisease-Free SurvivalmedicineHumansLaparoscopySurvival rateColectomyColectomyconversion laparoscopy colon cancermedicine.diagnostic_testbusiness.industryCancerGeneral MedicinePerioperativemedicine.diseaseConversion to Open SurgerySurgerySurvival RateSettore MED/18 - Chirurgia GeneraleTreatment Outcomecolonic neoplasms; disease-free survival; female; humans; male; operative time; survival rate; treatment outcome; colectomy; conversion to open surgery;laparoscopyColonic NeoplasmsRight ColectomyFemaleLaparoscopybusiness
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Prognostic value of right ventricular dysfunction or elevated cardiac biomarkers in patients with low-risk pulmonary embolism: a systematic review an…

2018

Abstract Aims Patients with acute pulmonary embolism (PE) classified as low risk by the Pulmonary Embolism Severity Index (PESI), its simplified version (sPESI), or the Hestia criteria may be considered for early discharge. We investigated whether the presence of right ventricular (RV) dysfunction may aggravate the early prognosis of these patients. Methods and results We did a systematic review and meta-analysis of studies including low-risk patients with acute PE to investigate the prognostic value of RV dysfunction. Diagnosis of RV dysfunction was based on echocardiography or computed tomography pulmonary angiography. In addition, we investigated the prognostic value of elevated troponin…

MaleComputed Tomography AngiographyVentricular Dysfunction Right030204 cardiovascular system & hematologySeverity of Illness Index0302 clinical medicineNatriuretic peptidePulmonary angiographyHospital MortalityRight ventricular dysfunctionAged 80 and overbiologyMortality rateHome treatmentMiddle AgedPrognosisTroponinPulmonary embolismEchocardiographyMeta-analysisAcute DiseaseCardiologyFemaleCardiology and Cardiovascular MedicineAdultmedicine.medical_specialtymedicine.drug_classFast Track Clinical ResearchRisk Assessment03 medical and health sciencesAnticoagulationInternal medicinemedicineHumansMortalityNatriuretic PeptidesRisk stratificationAgedbusiness.industryPulmonary embolismAnticoagulants030229 sport sciencesOdds ratiomedicine.diseaseTroponinConfidence intervalEditor's Choicebiology.proteinbusinessBiomarkersEuropean Heart Journal
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