Search results for "risk factor"

showing 10 items of 4321 documents

RIFLE classification as predictive factor of mortality in patients with cirrhosis admitted to intensive care unit.

2009

Background and Aim: To evaluate the association of the Risk, Injury, Failure, Loss and End-stage renal failure (RIFLE) score on mortality in patients with decompensated cirrho- sis admitted to intensive care unit (ICU). Methods: A cohort of 412 patients with cirrhosis consecutively admitted to ICU was classified according to the RIFLE score. Multivariable logistic regression analysis was used to evaluate the factors associated with mortality. Liver-specific, Acute Physiology and Chronic Health Evaluation (APACHE) II, Sequential Organ Failure Assessment (SOFA) and RIFLE scores on admission, were compared by receiver-operator characteristic curves. Results: The overall mortality during ICU st…

AdultLiver CirrhosisMalemedicine.medical_specialtyTime FactorsRisk AssessmentSensitivity and SpecificitySeverity of Illness Indexlaw.inventionHepatorenal syndromelawPredictive Value of TestsRisk FactorsInternal medicineCause of DeathEpidemiologymedicineHealth Status IndicatorsHumansRifleAPACHERetrospective StudiesHepatologybusiness.industryGastroenterologyAcute kidney injuryReproducibility of ResultsOdds ratioAPACHE cirrhosis intensive care unit MELD renal failure RIFLE SOFA.Acute Kidney InjuryMiddle Agedmedicine.diseasePrognosisIntensive care unitSurgeryIntensive Care UnitsLogistic ModelsROC CurveCohortFemalebusinessKidney disease
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Predictors of mortality in patients under treatment for chronic hepatitis B in Ethiopia: a prospective cohort study

2019

Abstract Background Antiviral treatment for chronic hepatitis B (CHB) is largely unavailable in sub-Saharan Africa; hence, little is known about the prognosis after initiating treatment in African CHB patients. In this study we aimed to assess predictors of mortality in one of the largest CHB cohorts in sub-Saharan Africa. Methods Two-hundred-and-seventy-six CHB patients who started treatment with tenofovir disoproxil fumarate at a public hospital in Ethiopia between March 18, 2015, and August 1, 2017, were included in this analysis. Patients were followed up until October 1, 2017, and deaths were ascertained through hospital records and telephone interview with relatives. Decompensated cir…

AdultLiver CirrhosisMalemedicine.medical_specialtyTime FactorsSurvivalAdolescentEpidemiologyPhysical examinationAntiviral therapyAntiviral AgentsBody Mass Index03 medical and health sciencesYoung Adult0302 clinical medicineHepatitis B ChronicInterquartile rangeRisk FactorsInternal medicineEpidemiologyMedicineHumansProspective Studieslcsh:RC799-869Prospective cohort studyTenofovirProportional Hazards Modelsmedicine.diagnostic_testbusiness.industryHazard ratioGastroenterologyAge FactorsGeneral MedicineHepatitis BHepatologyMiddle Agedmedicine.diseaseHepatitis BResource-limited settingsSurvival RateVDP::Medisinske Fag: 700::Helsefag: 800030220 oncology & carcinogenesislcsh:Diseases of the digestive system. Gastroenterology030211 gastroenterology & hepatologyFemaleEthiopiabusinessBody mass indexResearch Article
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Factors That Contribute or Impede the Physical Health Recovery of Women Exposed to Intimate Partner Violence: A Longitudinal Study

2012

Abstract Background Several cross-sectional studies have demonstrated the negative impact that intimate partner violence (IPV) has on the physical health of women. However, longitudinal studies are needed to establish the time course of this effect. This study assessed the physical health course of female IPV victims and established the factors that enhance or impede their recovery. Methods Women ( n  = 91) who participated in a previous cross-sectional study (T-1) and were either victims of physical/psychological IPV ( n  = 33) or psychological IPV ( n  = 23) were evaluated 3 years later (T-2). A control group of women ( n  = 35) was included for comparison. Structured interviews provided …

AdultLongitudinal studyHealth (social science)Health StatuseducationPoison controlbehavioral disciplines and activitiesSuicide preventionOccupational safety and healthInterviews as TopicSocial supportRisk FactorsSurveys and Questionnairesmental disordersMaternity and MidwiferyInjury preventionHumansMedicineLongitudinal StudiesCrime VictimsFamily Characteristicsbusiness.industryPublic Health Environmental and Occupational HealthSocial SupportObstetrics and GynecologyHuman factors and ergonomicssocial sciencesMiddle AgedSocioeconomic FactorsSpainCase-Control StudiesSpouse Abusepopulation characteristicsDomestic violenceFemalebusinessSocial psychologyFollow-Up StudiesClinical psychologyWomen's Health Issues
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The physician-patient relationship before cancer treatment: a prospective longitudinal study.

2003

Abstract Objectives . To evaluate quality of life before surgery for genital cancer to determine risk factors that might influence the physician–patient relationship. Methods . From 1993 until 2003, 129 women with cervical cancer entered this prospective study. Patients were contacted 1 to 5 days before surgery by a psychologist or psychotherapeutically trained physician on the surgical ward. The semistructured interview included questions on the patient's psychosocial well-being according to criteria of the biographic interview technique. The preoperative anxiety level was evaluated by the STAI and quality of life by the Cancer Rehabilitation Evaluation System (CARES) and EORTC questionnai…

AdultLongitudinal studymedicine.medical_specialtymedicine.medical_treatmentUterine Cervical NeoplasmsAnxietyQuality of lifePatient Education as TopicRisk FactorsmedicineHumansPsychologyLongitudinal StudiesProspective StudiesProspective cohort studyAgedCervical cancerPhysician-Patient RelationsPelvic exenterationbusiness.industryObstetrics and GynecologyCancerMiddle Agedmedicine.diseaseOncologyPhysical therapyQuality of LifeAnxietyFemalemedicine.symptombusinessPsychosocialGynecologic oncology
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The difference in risk of chronic pulmonary disease morbidity and mortality between former elite athletes and ordinary men in Finland.

2019

The impact of a history of competitive sports on later smoking behaviour and occurrence of chronic pulmonary diseases is poorly known. We investigated how a history of elite level sports predicted later pulmonary disease morbidity and mortality. Chronic pulmonary disease incidence was assessed from national hospital and cause-of-death registers from 1970 to 2015 among Finnish male former elite athletes (n = 2078) and matched controls (n = 1453) alive in 1970 (mean age 45.0 years). Hazard ratios (HRs) were calculated by Cox proportional hazards model. In 1985, cohort members reported on their smoking habits, engagement in physical activity/sports and physician-diagnosed chronic diseases. The…

AdultLung DiseasesMalemedicine.medical_specialtyChronic bronchitisCompetitive Behavior030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationComorbidity03 medical and health sciences0302 clinical medicineAge DistributionRisk FactorsInternal medicineCause of DeathmedicineHumansOrthopedics and Sports MedicineLongitudinal StudiesYoung adultExerciseFinlandProportional Hazards ModelsCOPDbiologyAthletesProportional hazards modelbusiness.industryHazard ratioSmoking030229 sport sciencesGeneral MedicineLength of StayMiddle Agedbiology.organism_classificationmedicine.disease3. Good healthSocioeconomic FactorsAthletesCohortChronic DiseasePhysical EndurancebusinessCohort studyEuropean journal of sport science
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Short-term outcomes of colorectal cancer surgery in older patients : a novel nomogram predicting postoperative morbi-mortality

2022

Abstract Purpose To analyze short-term outcomes of curative-intent cancer surgery in all adult patients diagnosed with colorectal cancer undergoing surgery from January 2010 to December 2019 and determine risk factors for postoperative complications and mortality. Methods Retrospective study conducted at a single tertiary university institution. Patients were stratified by age into two groups: < 75 years and ≥ 75 years. Primary outcome was the influence of age on 30-day complications and mortality. Independent risk factors for postoperative adverse events or mortality were analyzed, and two novel nomograms were constructed. Results Of the 1486 patients included, 580 were older (≥ 75 year…

AdultLung DiseasesPeripheral Vascular DiseasesNomogramsPostoperative ComplicationsRisk FactorsHumansSurgeryCàncer CirurgiaColorectal NeoplasmsPersones gransAgedRetrospective Studies
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Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease St…

2022

Correction to Lancet Gastroenterol Hepatol 2022; 7: 627-47. Lancet Gastroenterol Hepatol. 2022 Aug;7(8):704. doi: 10.1016/S2468-1253(22)00210-2. PMID: 35809605. Background: Colorectal cancer is the third leading cause of cancer deaths worldwide. Given the recent increasing trends in colorectal cancer incidence globally, up-to-date information on the colorectal cancer burden could guide screening, early detection, and treatment strategies, and help effectively allocate resources. We examined the temporal patterns of the global, regional, and national burden of colorectal cancer and its risk factors in 204 countries and territories across the past three decades. Methods: Estimates of incidenc…

AdultMED/42 - IGIENE GENERALE E APPLICATAIMPACTcolorectal cancerColorectal NeoplasmGBD 2019 Colorectal Cancer CollaboratorsHEREDITARYGlobal Burden of DiseaseCancer screeningDISPARITIESSDG 3 - Good Health and Well-beingCancer treatment strategiesRisk FactorsQuality-Adjusted Life YearCOLONGlobal studiesDALY GBD colorectal cancerrisk factorsHumansGlobal Burden of Disease StudyEarly Detection of CancerHepatologyMORTALITYGastroenterologyCancer incidence ratesMiddle AgedCancer burdenSURVIVAL/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSEXGENDERQuality-Adjusted Life YearsColorectal NeoplasmsHumanThe Lancet Gastroenterology & Hepatology
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Influence of the structural components of artificial turf systems on impact attenuation in amateur football players

2019

AbstractThe purpose of this research was to evaluate the influence of the structural components of different 3rd generation artificial turf football field systems on the biomechanical response of impact attenuation in amateur football players. A total of 12 amateur football players (24.3 ± 3.7 years, 73.5 ± 5.5 kg, 178.3 ± 4.1 cm and 13.7 ± 4.3 years of sport experience) were evaluated on three third generation artificial turf systems (ATS) with different structural components. ATS were composed of asphalt sub-base and 45 mm of fibre height with (ATS1) and without (ATS2) elastic layer or compacted granular sub-base, 60 mm of fibre height without elastic layer (ATS3). Two triaxial accelerome…

AdultMale0301 basic medicineAccelerationPoison controlSTRIDElcsh:MedicineFútbolArticleLower energyRunningYoung Adult03 medical and health sciences0302 clinical medicineFloors and FloorcoveringsSoccerArtificial turfHumanslcsh:ScienceMathematicsOrthodonticsEsportsFootball playersMultidisciplinaryAttenuationlcsh:RDeporteBone quality and biomechanicsBiomechanical Phenomena030104 developmental biologyRisk factorsAthletesFootball fieldSuperficies deportivas sintéticaslcsh:QEducació físicaAmateur030217 neurology & neurosurgeryInstalación deportiva
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Lack of evidence for a reciprocal interaction between bacterial and cytomegalovirus infection in the allogeneic stem cell transplantation setting

2016

Summary Pathogenic interactions between bacteria and cytomegalovirus (CMV) may potentially occur early after allogeneic stem cell transplantation (Allo-SCT). This possibility nevertheless has not been investigated in depth. This was a retrospective study that included 170 consecutive patients who underwent 173 Allo-SCTs. Both bacterial infection (most of which were bacteremic) and CMV DNAemia were detected in 78 Allo-SCTs (62.9%). In total, 51 and 32 episodes of bacterial infection preceded or occurred after CMV DNAemia detection, respectively. Both events were diagnosed concurrently in four Allo-SCTs. The cumulative incidence of bacterial infection (of any type) over the study period was c…

AdultMale0301 basic medicineAdolescent030106 microbiologyCongenital cytomegalovirus infectionCytomegalovirusBacteremiaYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsmedicineHumansTransplantation HomologousCumulative incidence030212 general & internal medicineAgedProportional Hazards ModelsRetrospective StudiesTransplantationbusiness.industryHematopoietic Stem Cell Transplantationvirus diseasesRetrospective cohort studyBacterial InfectionsCmv dnaemiaMiddle Agedmedicine.diseaseCytomegalovirus infectionTransplantationBacteremiaCytomegalovirus InfectionsDNA ViralImmunologyFemaleStem cellbusinessFollow-Up StudiesTransplant International
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Cholelithiasis in Patients with Gaucher Disease type 1: Risk Factors and the Role of ABCG5/ABCG8 Gene Variants

2016

Background & Aim: Patients with Gaucher disease type 1 (GD1) show an altered lipid profile and a certain degree of insulin resistance, which might contribute to cholelithiasis (CL) and could possibly be associated with ABCG5/ABCG8 gene variants. We aimed to investigate the prevalence of CL in Caucasian adult patients with GD1 and the possible risk factors, including gene variants of the ABCG5/ABCG8 genes.
 Methods: 61 Caucasian patients with GD1 (38 female/23male), aged 18-62 years and 61 healthy subjects matched for age, gender and BMI, without CL, for comparison of lipid profiles. Data before start of enzyme replacement therapy (ERT) were recorded: clinical, haematological, sever…

AdultMale0301 basic medicineHeterozygotemedicine.medical_specialtyAdolescentLipoproteinsmedicine.medical_treatmentSplenectomyABCG8030105 genetics & heredityGastroenterologyWhite PeopleYoung Adult03 medical and health sciencesInsulin resistanceGene FrequencyCholelithiasisRisk FactorsInternal medicineGenotypePrevalencemedicineHumansEnzyme Replacement TherapyGenetic Predisposition to DiseaseATP Binding Cassette Transporter Subfamily G Member 5Genetic Association StudiesGaucher Diseasemedicine.diagnostic_testRomaniabusiness.industryATP Binding Cassette Transporter Subfamily G Member 8HomozygoteGastroenterologyCase-control studyGenetic VariationEnzyme replacement therapyMiddle Agedmedicine.diseaseCross-Sectional StudiesPhenotypeCase-Control StudiesGlucosylceramidaseFemaleLipid profilebusinessDyslipidemiaJournal of Gastrointestinal and Liver Diseases
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