Search results for "riskinarviointi"

Assessing the influence of confounding biological factors when estimating bioaccumulation of PCBs with passive samplers in aquatic ecosystems

2017

Passive samplers are promising surrogates for organisms, mimicking bioaccumulation. However, several biological characteristics disturb the passive partitioning process in organisms by accelerating or restraining bioaccumulation, resulting in species-specific body residues of hydrophobic organic contaminants (HOCs). In addition to site-specific characteristics and HOC concentrations, age, sex, diet, biotransformation capability and habitat-specific characteristics may affect body residues. Two passive sampler types, polyethylene (PE) and polydimethylsiloxane (PDMS) were deployed in a PCB-contaminated freshwater lake water and sediment, respectively, to assess their bioaccumulation predictio…

Mammal assemblage composition predicts global patterns in emerging infectious disease risk

2021

Abstract As a source of emerging infectious diseases, wildlife assemblages (and related spatial patterns) must be quantitatively assessed to help identify high‐risk locations. Previous assessments have largely focussed on the distributions of individual species; however, transmission dynamics are expected to depend on assemblage composition. Moreover, disease–diversity relationships have mainly been studied in the context of species loss, but assemblage composition and disease risk (e.g. infection prevalence in wildlife assemblages) can change without extinction. Based on the predicted distributions and abundances of 4466 mammal species, we estimated global patterns of disease risk through …

A preliminary study on the ecotoxic potency of wastewater treatment plant sludge combining passive sampling and bioassays.

2021

Highlights • The passive samplers collected bioavail able and bioaccessible chemicals from the WWTP sludge samples. • The sampler extracts were acutely and chronically toxic to water flea. • The sampler extracts were cytotoxic and genotoxic. • The sludge treatment such as composting and digesting diminished the toxicity. • Effect-based methods should be part of the risk assessment of sludge recycling. Sewage sludge is an inevitable byproduct produced in wastewater treatment. Reusing nutrient-rich sludge will diminish the amount of waste ending in soil dumping areas and will promote circular economy. However, during sewage treatment process, several potentially harmful organic chemicals are …

Toxicity of Mining-Contaminated Lake Sediments to Lumbriculus variegatus

2021

AbstractBoreal lakes with soft water and low buffering capacity are susceptible to excess ion loading resulting from metal mining. The impact of two Finish mining sites in downstream lakes was assessed with a chronic sediment toxicity test using a laboratory-reared freshwater Lumbriculus variegatus (Oligochaeta). The test organisms were exposed to mining-contaminated natural lake sediments and hypolimnion water (HLW) or artificial freshwater (AFW) as overlying water in two independent experimental setups. In both test setups, growth and reproduction of L. variegatus were lower in sediments from the lakes receiving high amount of mining effluents from the mines nearby. In the biomining site,…

Early discharge and home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban: an international multi…

2020

Abstract Aims To investigate the efficacy and safety of early transition from hospital to ambulatory treatment in low-risk acute PE, using the oral factor Xa inhibitor rivaroxaban. Methods and results We conducted a prospective multicentre single-arm investigator initiated and academically sponsored management trial in patients with acute low-risk PE (EudraCT Identifier 2013-001657-28). Eligibility criteria included absence of (i) haemodynamic instability, (ii) right ventricular dysfunction or intracardiac thrombi, and (iii) serious comorbidities. Up to two nights of hospital stay were permitted. Rivaroxaban was given at the approved dose for PE for ≥3 months. The primary outcome was sympto…

Handgrip strength is inversely associated with fatal cardiovascular and all-cause mortality events

2020

Purpose: We aimed to assess the associations of handgrip strength (HS) with cardiovascular and all-cause mortality and whether adding data on HS to cardiovascular disease (CVD) risk factors is associated with improvement in CVD mortality prediction. Design: Handgrip strength was assessed in a population-based sample of 861 participants aged 61–74 years at baseline. Relative HS was obtained by dividing the absolute value by body weight. Results: During a median (interquartile range) follow-up of 17.3 (12.6–18.4) years, 116 fatal coronary heart diseases (CHDs), 195 fatal CVDs and 412 all-cause mortality events occurred. On adjustment for several risk factors, the hazard ratios (95% confidence…

Integrating risk management tools for regional forest planning : an interactive multiobjective value at risk approach

2018

In this paper, we present an approach employing multiobjective optimization to support decision making in forest management planning under risk. The primary objectives are biodiversity and timber cash flow, evaluated from two perspectives: the expected value and the value-at-risk (VaR). In addition, the risk level for both the timber cash flow and biodiversity values are included as objectives. With our approach, we highlight the trade-off between the expected value and the VaR, as well as between the VaRs of the two objectives of interest. We employ an interactive method in which a decision maker iteratively provides preference information to find the most preferred management plan and lea…

AQUATOX - ecological risk assessment model : a tool for impact assessment for waters

2009

Satamasedimenttien ekotoksikologinen riskinarviointi

2008

Kokonaistoksisuuden testauksen soveltuvuus suomalaisten yhdyskuntajätevesien riskinarviointiin ja tarkkailuun

2016

Jätevesissä on monia erilaisia yhdisteitä, joista osa on ympäristölle haitallisia. Kemikaalien yhteisvaikutuksien riskinarviointi ja tarkkailu on mahdotonta pelkkien fysikaalis-kemiallisten testien voimin. Täten onkin kehitelty biologisia menetelmiä, joiden avulla näiden monimuotoisten seosten haitallisuutta voidaan tarkkailla. Vaikka maailmalla jätevesien kokonaistoksisuuden testausta on käytetty jo 1980-luvulta lähtien, menetelmää on toistaiseksi hyödynnetty Suomessa vain vähänlaisesti. Tämän tutkielman tavoitteena oli tutkia kokonaistoksisuuden testauksen soveltuvuutta suomalaisten yhdyskuntajätevesien analysointiin. Biotestien luotettavuutta tarkasteltiin niiden toistettavuutta vertaile…