Search results for "rosa"

Localization of MRX82: A new nonsyndromic X-linked mental retardation locus to Xq24-q25 in a Basque family

2004

Clinical and molecular studies are reported on a Basque family (MRX82) with nonsyndromic X-linked mental retardation (XLMR) in five affected males. A total of 38 microsatellite markers were typed. The XLMR locus has been linked to DXS8067, DXS1001, DXS425, DXS7877, and DXS1183 with a maximum LOD score of 2.4. The haplotype studies and multipoint linkage analysis suggest a localization of the MRX82 locus to an interval of 7.6 Mb defined by markers DXS6805 and DXS7346, in Xq24 and Xq25, respectively. No gene contained in this interval has been so far associated with nonsyndromic mental retardation, except for GRIA3, disrupted by a balanced translocation in a female patient with bipolar affect…

N-Methyl-4-(4-nitrophenyl)-N-nitroso-1,3-thiazol-2-amine

2017

The title compound, C10H8N4O3S, is almost planar [dihedral angle between the rings = 2.2 (2)°; r.m.s. deviation for the non-H atoms = 0.050 Å]. In the crystal, C—H...O and C—H...N hydrogen bonds link the molecules into (10-2) layers.

Ankkalinna - portti kahden ulottuvuuden välillä fantastisten maailmojen ilmeneminen Don Rosan Disney-sarjakuvissa

2009

Various luck of the reception of the Classical Literature: The cases of Ramón Goméz de la Serna y Francisco Ayala

2020

Se recogen en este trabajo referencias a la literatura clásica, explícitas o implícitas, en dos auto- res españoles cuyas respectivas obras resultan en muchos aspectos antagónicas: a sus diferentes trayectorias vitales, ya que pertenecen a generaciones distintas, además de que el más joven (Ayala 1906-2009) sobrevivió al otro (Gómez dela Serna, 1888-1963)en más de cuarenta años, se une una muy opuesta práctica de la creación literaria. No ha de sorprender, por tanto, que ambos muestren diferentes acercamientos a la literatura clásica. This paper presents the reception of the Classical literature, in a more or less explicit way, in two Spanish prose-writers that created quite opposite litera…

XMM-Newton observations of the young open cluster Blanco 1. II. X-ray time variability and flares.

2005

We study the X-ray variability of the young open cluster Blanco 1 observed with the EPIC camera on board the XMM-Newton X-ray observatory. The time coverage of EPIC observations has allowed us to address short time scale (hours) variability, while the comparison with previous ROSAT observations has allowed us to investigate the variability on time scale of six years. On the time scale of hours, dM stars of the cluster are more variable than solar-mass stars. The main features of X-ray light curves in dM stars appear to be essentially flare-like events with a typical duration of the order of a few ks, while dF-dG stars show smooth variations. Two intense flares were observed in the ZS76 clus…

Effect of antibodies against cytochrome P-450 on demethylation and denitrosation of N-nitrosodimethylamine and N-nitrosomethylaniline.

1988

Rat liver microsomes which were induced either with ethanol or PB were incubated with NDMA or NMA. Formaldehyde generation and nitrite formation were measured as metabolic parameters for oxidative bioactivation and denitrosation, respectively. The influence of antiserum PB3a1 and PB22 containing antibodies against the corresponding cytochrome P-450 species on both metabolic functions was investigated. The results showed that the influence on formaldehyde production and denitrosation varied independently in that both parameters were either not affected, or influenced in an opposite way, or inhibited to a different degree. Especially remarkable was the 80% inhibition of formaldehyde generatio…

Development and localization of microsatellite markers for the sibling species Chironomus riparius and Chironomus piger (Diptera: Chironomidae)

2006

Five variable microsatellite loci are reported for the nonbiting midge species Chironomus riparius and Chironomus piger. All loci show considerable intraspecific variation and species-specific alleles, which allow to discriminate among the two closely related species and their interspecific hybrids, and to estimate genetic diversity within and between populations. Additionally, the loci were localized on C. riparius polytene chromosomes to verify their single copy status and investigate possible chromosomal linkage. The described markers are used in different studies with regard to population and ecological genetics and evolutionary ecotoxicology of Chironomus.

Genetic structure in the Mediterranean seagrass Posidonia oceanica: disentangling past vicariance events from contemporary patterns of gene flow

2010

The Mediterranean Sea is a two-basin system, with the boundary zone restricted to the Strait of Sicily and the narrow Strait of Messina. Two main population groups are recognized in the Mediterranean endemic seagrass Posidonia oceanica, corresponding to the Western and the Eastern basins. To address the nature of the East-West cleavage in P. oceanica, the main aims of this study were: (i) to define the genetic structure within the potential contact zone (i.e. the Strait of Sicily) and clarify the extent of gene flow between the two population groups, and (ii) to investigate the role of present water circulation patterns vs. past evolutionary events on the observed genetic pattern. To achiev…

Somatic loss of an EXT2 gene mutation during malignant progression in a patient with hereditary multiple osteochondromas

2015

Multiple osteochondromas (MO) is an autosomal-dominant skeletal disorder caused by mutations in the exostosin-1 ( EXT1 ) or exostosin-2 ( EXT2 ) genes. In this study, we report the analysis of the mutational status of the EXT2 gene in tumor samples derived from a patient affected by hereditary MO, documenting the somatic loss of the germline mutation in a giant chondrosarcoma and in a rapidly growing osteochondroma. The sequencing of all exons and exon–intron junctions of the EXT1 and EXT2 genes from blood DNA of the proband did not reveal any mutation in the EXT1 gene but did demonstrate the presence of the transition point mutation c.67C > T in the EXT2 gene, determining the introduction …

The REFLEX galaxy cluster survey VIII. Spectroscopic observations and optical atlas

2009

We present the final data from the spectroscopic survey of the ROSAT-ESO Flux-Limited X-ray (REFLEX) catalog of galaxy clusters. The REFLEX survey covers 4.24 steradians (34% of the entire sky) below a declination of 2.5 deg and at high Galactic latitude (|b| > 20 deg). The REFLEX catalog includes 447 entries with a median redshift of 0.08 and is better than 90% complete to a limiting flux fx = 3x10^{-12} erg s^{-1} cm^{-2} (0.1 to 2.4 keV), representing the largest statistically homogeneous sample of clusters drawn from the ROSAT All-Sky Survey (RASS) to date. Here we describe the details of the spectroscopic observations carried out at the ESO 1.5 m, 2.2 m, and 3.6 m telescopes, as wel…