Search results for "routing"
showing 10 items of 587 documents
Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy.
2010
Aims Currently, it is still unclear which mechanisms drive metabolic benefits after angiogenic gene therapy. The side-effect profile of efficient angiogenic gene therapy is also currently incompletely understood. In this study, the effects of increasing doses of adenoviral (Ad) vascular endothelial growth factor-A (VEGF-A) were evaluated on vascular growth, metabolic benefits, and systemic side effects. Methods and results Adenoviral vascular endothelial growth factor-A or AdLacZ control was injected intramuscularly (109–1011 vp/mL) or intra-arterially (5 × 1011 vp/mL) into rabbit ( n = 102) hindlimb muscles and examined 6 or 14 days later. Blood flow, tissue oedema, metabolic benefits, and…
Vehicle routing problems with drones equipped with multi-package payload compartments
2022
The vehicle routing problem with drones (VRP-D) consists of designing combined truck-drone routes and schedules to serve a set of customers with specific requests and time constraints. In this paper, VRP-D is extended to include a fleet of drones equipped with multi-package payload compartments to serve more customers on a single trip. Moreover, a drone can return to a truck, different from the one from which it started, to swap its depleted battery and/or to pick up more packages. This problem, denoted as VRP-D equipped with multi-package payload compartments (VRP-D-MC), aims to maximize total profit. In this work, an adaptive multi-start simulated annealing (AMS-SA) metaheuristic algorith…
Joint Route Planning under Varying Market Conditions
2006
Purpose - To provide empirical evidence on the level of savings that can be attained by joint route planning and how these savings depend on specific market characteristics.Design/methodology/approach - Joint route planning is a measure that companies can take to decrease the costs of their distribution activities. Essentially, this can either be achieved through horizontal cooperation or through outsourcing distribution to a Logistics Service Provider.The synergy value is defined as the difference between distribution costs in the original situation where all entities perform their orders individually, and the costs of a system where all orders are collected and route schemes are set up si…
Privacy-preserving scheme for mobile ad hoc networks
2011
This paper proposes a decentralized trust establishment protocol for mobile ad hoc networks (MANETs), where nodes establish security associations. In order to achieve privacy and security, we use homomorphic encryption and polynomial intersection so as to find the intersection of two sets. The first set represents a list of recommenders of the initiator and the second set is a list of trusted recommenders of the responder. The intersection of the sets represents a list of nodes that recommend the first node and their recommendations are trusted by the second node. In our experimental results we show that our scheme is effective even if there are 30 trusted nodes.
Castadiva: A Test-Bed Architecture for Mobile AD HOC Networks
2007
Evaluating and deploying all sorts of protocols and applications designed for wireless ad hoc networks in a real environment is an important and urgent task. Traditionally, all the proposals made rely solely on simulator results. However, as different research groups develop different solutions to solve problems related to these new networks, it becomes more and more important to migrate the proposed solutions to a real environment. In this work we present Castadiva, a test-bed architecture that allows validating software solutions for ad hoc networks using low-cost, of the-shelf devices and open source software. Through a friendly user interface, Castadiva offers the possibility to define …
Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain
2021
The formation of new blood vessels and the establishment of vascular networks are crucial during brain development, in the adult healthy brain, as well as in various diseases of the central nervous system. Here, we describe a step-by-step protocol for our recently developed method that enables hierarchical imaging and computational analysis of vascular networks in postnatal and adult mouse brains. The different stages of the procedure include resin-based vascular corrosion casting, scanning electron microscopy, synchrotron radiation and desktop microcomputed tomography imaging, and computational network analysis. Combining these methods enables detailed visualization and quantification of t…
A coupled cluster study of the 1 1A1g and 1 1B2u states of benzene
1998
A theoretical investigation of the equilibrium structures and harmonic frequencies of the 1 1A1g and 1 1B2u states of benzene is presented. The performance of coupled cluster singles (CCS), the recently proposed CC2 model, and coupled cluster singles and doubles (CCSD) is compared. The CC2 ground and excited states frequencies are a significant improvement of the CCS results and are relatively close to the CCSD results. A comparative analysis of the vibrations in the two electronic states of both C6H6 and C6D6 is presented. The reliability of predicted shifts in harmonic frequencies between the two states and isotopic shifts is estimated on the basis of the convergence in the CCS, CC2, and …
Parallel and Distributed Resource Allocation With Minimum Traffic Disruption for Network Virtualization
2017
Wireless network virtualization has been advocated as one of the most promising technologies to provide multifarious services and applications for the future Internet by enabling multiple isolated virtual wireless networks to coexist and share the same physical wireless resources. Based on the multiple concurrent virtual wireless networks running on the shared physical substrate, service providers can independently manage and deploy different end-users services. This paper proposes a new formulation for bandwidth allocation and routing problem for multiple virtual wireless networks that operate on top of a single substrate network to minimize the operation cost of the substrate network. We …
Rates of convergence to equilibrium for collisionless kinetic equations in slab geometry
2017
This work deals with free transport equations with partly diffuse stochastic boundary operators in slab geometry. Such equations are governed by stochastic semigroups in $L^{1}$ spaces$.\ $We prove convergence to equilibrium at the rate $O\left( t^{-\frac{k}{2(k+1)+1}}\right) \ (t\rightarrow +\infty )$ for $L^{1}$ initial data $g$ in a suitable subspace of the domain of the generator $T$ where $k\in \mathbb{N}$ depends on the properties of the boundary operators near the tangential velocities to the slab. This result is derived from a quantified version of Ingham's tauberian theorem by showing that $F_{g}(s):=\lim_{\varepsilon \rightarrow 0_{+}}\left( is+\varepsilon -T\right) ^{-1}g$ exists…
A high-resolution layer-wise discontinuous Galerkin formulation for multilayered composite plates
2020
Abstract In this work, a novel high-resolution formulation for multilayered composite plates is presented. The formulations is referred to as high-resolution since it combines (i) Layer-Wise plate theories, which are based on a per-layer, high-order expansion of the primary variables throughout the plate’s thickness, providing a detailed layer-level description of the sought solution; (ii) The discontinuous Galerkin method, a numerical approach based on a discontinuous representation of the unknown fields over the mesh elements and on the introduction of boundary integral operators enforcing inter-element continuity, which allow the natural treatment of high-order mesh elements and provide …