Search results for "scaffold"
showing 10 items of 470 documents
Sviluppo di spugne bioerodibili multifunzionali per la promozione di processi riparativi mediante il rilascio controllato di agenti antibiotici e ant…
2023
La salute delle strutture molli e dure del cavo orale è essenziale non solo per preservare le funzioni ad esse direttamente associate, ma anche per promuovere la salute generale dell’organismo. Tra le problematiche di maggiore interesse clinico a carico della cavità orale ritroviamo: i) le complicazioni post-operatorie che possono verificarsi a seguito di comuni avulsioni dentali che, se non trattate tempestivamente, possono sfociare in gravi parodontiti; ii) i fenomeni di osteonecrosi a carico di mascella e mandibola associate a trattamenti farmacologici nonché alla radioterapia; iii) il carcinoma orale a cellule squamose (OSCC) che è tra i più aggressivi tumori del collo e della testa, ca…
HYBRID SYSTEMS FOR TISSUE ENGINEERING
2009
Microfibers obtained by electrospinning of alpha, beta poly(N-2-hydroxyethyl)-DL-aspartamide-g-polylactic acid for potential use in tissue reconstruc…
2009
ANTICANCER RELEASING FILMS AND POROUS SCAFFOLDS BASED ON PHYSICALLY ASSEMBLED HYALURONIC ACID DERIVATIVES
2012
Micro Scale Based Mechanical Models for Electrospun Poly (Ester Urethane) Urea Scaffolds.
2009
Micro scale based mechanical models can provide a tool to guide tissue engineering scaffold design and to investigate on how the cellular mechanical and metabolic response are related to local micro-structural deformations. The present study proposes a novel approach to automatically collect micro-architectural data from SEM images of electrospun poly (ester urethane) urea (PEUU) and to recreate statistically equivalent scaffold mechanical models. Sets of contiguous SEM images for each of the three mandrel velocities (1.5, 4.5, 9.0 m/s) were analyzed. A combination of thresholding and morphological procedures enabled fibers overlaps to be detected. The algorithm precision was tested on regu…
Fabrication Techniques for Electrospun Polyurethane Scaffolds that Generate Valve Leaflet Mechanical Properties.
2010
A Structural Deterministic Model for Electrospun Scaffolds.
2009
Analysis of Electrospun Scaffolds Micro - Architectural Data.
2009
STRUCTURAL DETERMINISTIC MODELING DESIGN AND FABRICATION OF ELECTROSPUN SCAFFOLDS FOR SOFT TISSUE ENGINEERING
2011
The research fields of tissue engineering, biomechanics and regenerative medicine continue to evolve in response to the ever growing need for tissue replacement options. These fields aim to restore, maintain, or improve tissue or whole organ function. This doctoral studies focus on the development and experimental validation of a structural deterministic modeling strategy to: A) guide tissue engineering scaffold design, B) provide a better understanding of cellular mechanical and metabolic response to local micro-structural deformations. Targeted clinical application was the pulmonary heart valve. Electrospinning was selected as the optimal platform technology to implement, validate and tes…