Search results for "scale"
showing 10 items of 5180 documents
A Universal Length-Dependent Vibrational Mode in Graphene Nanoribbons
2019
Graphene nanoribbons (GNRs) have attracted considerable interest as their atomically tunable structure makes them promising candidates for future electronic devices. However, obtaining detailed information about the length of GNRs has been challenging and typically relies on low-temperature scanning tunneling microscopy. Such methods are ill-suited for practical device application and characterization. In contrast, Raman spectroscopy is a sensitive method for the characterization of GNRs, in particular for investigating their width and structure. Here, we report on a length-dependent, Raman active low-energy vibrational mode that is present in atomically precise, bottom-up synthesized armch…
Rational Design of Thermoresponsive Microgel Templates with Polydopamine Surface Coating for Microtissue Applications.
2021
Functional microgels provide a versatile basis for synthetic in vitro platforms as alternatives to animal experiments. The tuning of the physical, chemical, and biological properties of synthetic microgels can be achieved by blending suitable polymers and formulating them such to reflect the heterogenous and complex nature of biological tissues. Based on this premise, this paper introduces the development of volume-switchable core-shell microgels as 3D templates to enable cell growth for microtissue applications, using a systematic approach to tune the microgel properties based on a deep conceptual and practical understanding. Microscopic microgel design, such as the tailoring of the microg…
Extreme precipitation events over northern Italy. Part II : Dynamical precursors
2021
The connection between weather extremes and Rossby wave packets (RWP) has been increasingly documented in recent years. RWP propagation and characteristics can modulate the midlatitude weather, setting the scene for temperature and precipitation extremes and controlling the geographical area affected. Several studies on extreme precipitation events (EPEs) in the Alpine area reported, as the main triggering factor, a meridionally elongated upper‐level trough as part of an incoming Rossby wave packet. In this work, we investigate a wide number of EPEs occurring between 1979 and 2015 in northern‐central Italy. The EPEs are subdivided into three categories (Cat1, Cat2, Cat3) according to thermo…
The WHO-5 Well-Being Index – Validation based on item response theory and the analysis of measurement invariance across 35 countries.
2020
Abstract Background The five-item World Health Organization Well-Being Index (WHO-5) is a frequently used brief standard measure in large-scale cross-cultural clinical studies. Despite its frequent use, some psychometric questions remain that concern the choice of an adequate item response theory (IRT) model, the evaluation of reliability at important cutoff points, and most importantly the assessment of measurement invariance across countries. Methods Data from the 6th European Working Condition survey (2015) were used that collected nationally representative samples of employed and self-employed individuals (N = 43,469) via computer-aided personal interviews across 35 European countries. …
Análisis biomecánico de las actividades de subir y bajar escaleras en personas con patologías de rodilla
2016
La patología de la rodilla produce discapacidad para las actividades de la vida diaria, lo cual supone un reto médico, social y económico creciente. Es necesario contar con mejores herramientas de valoración con la finalidad de evaluar los nuevos tratamientos y protocolos, orientar mejor los programas para cada paciente y hacerlos más eficaces y eficientes. Las técnicas biomecánicas se utilizan para la valoración funcional de las personas con patologías de rodilla. El objetivo del trabajo es mejorar el conocimiento sobre las repercusiones funcionales que produce la patología de rodilla en las actividades de subir y bajar escaleras. Para ello se ha desarrollado un protocolo de valoración que…
Search for a Dark Leptophilic Scalar in e(+) e(-) Collisions
2020
Many scenarios of physics beyond the standard model predict the existence of new gauge singlets, which might be substantially lighter than the weak scale. The experimental constraints on additional scalars with masses in the MeV to GeV range could be significantly weakened if they interact predominantly with leptons rather than quarks. At an e+e- collider, such a leptophilic scalar (φL) would be produced predominantly through radiation from a τ lepton. We report herein a search for e+e-→τ+τ-φL, φL→ℓ+ℓ- (ℓ=e, μ) using data collected by the BABAR experiment at SLAC. No significant signal is observed, and we set limits on the φL coupling to leptons in the range 0.04<mφL<7.0 GeV. These bounds s…
Wilson’s Disease: Facing the Challenge of Diagnosing a Rare Disease
2021
Wilson disease (WD) is a rare disorder caused by mutations in ATP7B, which leads to the defective biliary excretion of copper. The subsequent gradual accumulation of copper in different organs produces an extremely variable clinical picture, which comprises hepatic, neurological psychiatric, ophthalmological, and other disturbances. WD has a specific treatment, so that early diagnosis is crucial to avoid disease progression and its devastating consequences. The clinical diagnosis is based on the Leipzig score, which considers clinical, histological, biochemical, and genetic data. However, even patients with an initial WD diagnosis based on a high Leipzig score may harbor other conditions th…
Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: study protocol for a randomized controlled trial
2021
Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program i…
Event Horizon Telescope imaging of the archetypal blazar 3C 279 at an extreme 20 microarcsecond resolution
2020
Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Open Access funding provided by Max Planck Society.--All authors: Kim, Jae-Young; Krichbaum, Thomas P.; Broderick, Avery E.; Wielgus, Maciek; Blackburn, Lindy; Gómez, José L.; Johnson, Michael D.; Bouman, Katherine L.; Chael, Andrew; Akiyama, Kazunori; Jorstad, Svetlana; Marscher, Alan P.; Issaoun, Sara; Janssen, Michael; Chan, Chi-kwan; Savolainen, Tuomas; Pesce, Dominic W.; Özel, Feryal; Alberdi, Antxon; Alef, Walt…
Are remote sensing evapotranspiration models reliable across South American ecoregions?
2021
Many remote sensing-based evapotranspiration (RSBET) algorithms have been proposed in the past decades and evaluated using flux tower data, mainly over North America and Europe. Model evaluation across South America has been done locally or using only a single algorithm at a time. Here, we provide the first evaluation of multiple RSBET models, at a daily scale, across a wide variety of biomes, climate zones, and land uses in South America. We used meteorological data from 25 flux towers to force four RSBET models: Priestley–Taylor Jet Propulsion Laboratory (PT-JPL), Global Land Evaporation Amsterdam Model (GLEAM), Penman–Monteith Mu model (PM-MOD), and Penman–Monteith Nagler model (PME-VI).…