Search results for "screening"
showing 10 items of 1150 documents
Colonoscopic screening of first-degree relatives of patients with large adenomas: increased risk of colorectal tumors.
2007
International audience; Background & Aims: The risk of developing colorectal neoplasia is not well established among family members of individuals with large adenomas and screening strategies remain under debate in this population. This study aimed at quantifying the risk of colorectal adenomas and cancers using colonoscopic screening in first-degree relatives of patients with large adenomas. Methods: This case-control study was performed in 18 endoscopic units of French non-University Hospitals. A colonoscopy was offered to first-degree relatives of 306 index cases with adenomas ≥ 10 mm, if they were alive, aged 40-75 and could be contacted by the index case. Among 674 relatives meeting th…
Development of Bioimage Analysis tools for the study of neurogenesis and neurodegeneration
2021
ANTECEDENTES La combinación sinérgica de métodos automatizados de captura y análisis de bioimagen está emergiendo como un enfoque de vanguardia para abordar muchas cuestiones biológicas. Sin embargo, hay muchos campos en los que estas técnicas aún no se implementan y, en cambio, todavía se basan en la inspección visual y el análisis manual, que inevitablemente limitan el rendimiento alcanzable y son más propensos a introducir el sesgo del investigador. Por lo tanto, aún queda un gran esfuerzo por hacer en la difusión del uso de tecnologías de bioimagen de vanguardia en los campos de las ciencias de la vida con una gran dependencia de métodos de microscopía. En la presente tesis, nuestro obj…
Reverse Screening on Indicaxanthin from Opuntia ficus-indica as natural chemoactive and chemopreventive agent
2018
Indicaxanthin is a bioactive and bioavailable betalain pigment extracted from Opuntia ficus indica fruits. Indicaxanthin has pharmacokinetics proprieties, rarely found in other phytochemicals, and it has been demonstrated that it provides a broad-spectrum of pharmaceutical activity, exerting antiproliferative, anti-inflammatory and neuromodulator effects. The discovery of the Indicaxanthin physiological targets plays an important role in understanding the biochemical mechanism. In this study, combined reverse pharmacophore mapping, reverse docking, and text-based database search identified Inositol Trisphosphate 3-Kinase (ITP3K-A), Glutamate carboxypeptidase II (GCPII), Leukotriene-A4 hydro…
Contributions à l'analyse et à l'interprétation des images : Extraction et représentation de caractéristiques
2016
Ce mémoire, rédigé en vue de l'obtention de l'Habilitation à Diriger des Recherches (HDR), offre un aperçu des travaux de recherche et d’encadrement que j’ai pu mener depuis l'obtention de mon doctorat. Il montre la diversité des champs d’application et de recherche (en vision et en imagerie médicale) que j’ai pu couvrir , ainsi que mon implication dans l’encadrement doctoral.Mes activités de recherche se divisent en deux grandes parties. D'une part, l'analyse de scènes dynamiques, à savoir la détection de regions d'intérêt dans des séquences d'images, pour réduire la taile des données à traiter, et la détection et le suivi d'objets mobiles à l'aide de caméras de diverses natures (perspecti…
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
2011
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. Common sequence variants have recently joined rare structural polymorphisms as genetic factors with strong evidence for association with schizophrenia. Here we extend our previous genome-wide association study and meta-analysis (totalling 7 946 cases and 19 036 controls) by examining an expanded set of variants using an enlarged follow-up sample (up to 10 260 cases and 23 500 controls). In addition to previously reported alleles in the major histocompatibility complex region, near neurogranin (NRGN) and in an intron of transcription factor 4 (TCF4), we find two novel variants show…
Evaluation of oleander accessions for resistance to Pseudomonas savastanoi pv. nerii
2006
Nine oleander accessions were evaluated for resistance to Pseudomonas savastanoi pv. nerii, causal agent of the oleander knot disease. None of the accessions was resistant when tested with three bacterial strains of different virulence, but they varied significantly in the severity of symptoms induced by these strains. The most susceptible accessions "Dark Salmon" (dark salmon flower) showed deformation of stems, leaves and seed pods and secondary knots on aerial parts, whereas the least susceptible one "White" (white flower), inoculated with the least virulent strain, showed neither localized knots at the inoculation point nor secondary symptoms. In this study an in vitro test, based on pr…
Could a Behavioral Model Explain Adherence to Second-Level Colonoscopy for Colon Cancer Screening? Results of a Cross-Sectional Study of the Palermo …
2022
According to Italian Essential Levels of Assistance (ELA), a colonoscopy is strongly recommended after a positive fecal occult blood test (FOBT) due to its effectiveness in early colorectal cancer detection. Despite the evidence, the Palermo province population (Italy), after a positive FOBT, have a lower colonoscopy adherence compared to Italian standards. This cross-sectional study analyzed patients’ perceptions of colonoscopy procedures to understand the reasons for non-adherence. Patients with a positive FOBT who did not undergo a colonoscopy within the national organized screening program were administered a telephone interview based on the Health Belief Model (HBM) questionnaire. The …
Detección de la condición TDAH en niños/as de la Provincia de Cuenca mediante la Escala Magallanes de Detección de Déficit de Atención (EMA-DDA).
2015
Actualmente nuestra sociedad sigue empleando el término “niño hiperactivo” como síntoma de un trastorno, indicio de posible TDAH, hecho que lleva a confusión a muchos padres y maestros. Es de suma importancia que aclaremos o remarquemos, a nivel social e incluso profesional, la diferencia entre niños inquietos, ansiosos o inadaptados emocionales y socialmente de aquellos que presentan un comportamiento y funcionamiento cognitivo que puede considerarse patológico, debido a la elevada intensidad de una sintomatología que puede generar problemas de adaptación, (Orjales Villar, I. 2003: Trastorno por déficit de atención/ hiperactividad TDAH), para poder ofrecerles una atención educativa y socia…
Applicants in a real-life selection context : their personality types, reactions to the process, and faking
2012
Developmental pathways of language development : a longitudinal predictive study from prelinguistic stage to outcome at school entry
2017
This research focused on the pathways of development during the prelinguistic stage and from prelinguistic development to later language ability. The first goal was to follow and describe the development of several prelinguistic communication skills during the first two years of life (Studies I and II). The second goal was to examine the predictive relations between this development and language ability and difficulties, as well as memory, up to school age (Studies I, II, and III). The third goal evaluated the feasibility of parental screening in identifying children at risk for language and communication difficulties (Studies I, II, and III). Prelinguistic skills were followed with a paren…