Search results for "script"

Detection of the norovirus variants GGII.4 hunter and GGIIb/hilversum in Italian children with gastroenteritis.

2006

Noroviruses (NoVs) are important enteric pathogens of humans. Although they exhibit an impressive genetic diversity, few NoV strains appear to predominate worldwide. Limited epidemiological data are available on NoV gastroenteritis in Italy. In this study, we assessed the prevalence of human NoV in Italian children with gastroenteritis by using a reverse-transcription nested polymerase chain reaction (RT-PCR) assay specific for the RNA-dependent RNA polymerase (RdRp) on faecal samples collected throughout the 2004 surveillance activity in Palermo, Italy. NoVs were detected in 47% of the stool samples obtained from children <5 years age, admitted to hospital with acute non-bacterial gastroen…

Use of ICS in COPD: From Blockbuster Medicine to Precision Medicine

2017

Chronic obstructive pulmonary disease (COPD) is a major cause of mortality worldwide, whose burden is expected to increase in the next decades, because of numerous risk factors, including the aging of the population. COPD is both preventable and treatable by an effective management including risk factor reduction, prevention, assessment, and treatment of acute exacerbations and co-morbidities. The available agents approved for COPD treatment are long-acting or ultra-long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) bronchodilators, as well as inhaled corticosteroids (ICS) in combination with LABAs. ICS use has been restricted only to selected COPD patients by th…

A Proposal to estimate the roaming–dog Total in an urban area through a PPSWOR spatial sampling with sample size greater than two

2018

Sex and Sexuality

2021

Abstract Symbolic interactionist approaches to sexuality state that human beings become sexual as they become whatever else and learn sexual definitions and sexual meanings just like they learn any other kind of meaning. Therefore, interactionist analysis shifts the focus of inquiry into sex from being sexual towards becoming sexual, which takes into account how sexualities are produced, organized, and negotiated, rather than tracing their sources in an immutable (conception of) nature. Sociosexual meanings give people the chance to define themselves and others sexually, to construct their sexual self and doing sexual things together in the shaping of more complex sexual choreographies and …

Introduzione. I copioni sessuali. Storia, analisi e applicazioni

2017

Il saggio introduttivo presenta la prospettiva sociologica dei copioni sessuali ed elabora i contributi presenti in volume.

miRNA Signature and Dicer Requirement during Human Endometrial Stromal Decidualization In Vitro

2012

Decidualization is a morphological and biochemical transformation of endometrial stromal fibroblast into differentiated decidual cells, which is critical for embryo implantation and pregnancy establishment. The complex regulatory networks have been elucidated at both the transcriptome and the proteome levels, however very little is known about the post-transcriptional regulation of this process. miRNAs regulate multiple physiological pathways and their de-regulation is associated with human disorders including gynaecological conditions such as endometriosis and preeclampsia. In this study we profile the miRNAs expression throughout human endometrial stromal (hESCs) decidualization and analy…

MASCHILITÀ OMOSESSUALI TRA SESSO E AMICIZIA. COME LE ‘DATING APPS’ RISCRIVONO I COPIONI SESSUALI NEL XXI SECOLO

2021

This paper analysis sexual scripts theory in relation to gay men courtship, love relationships, and casual sex. The aim is to understand how gay masculinity is evolving in the 21st Century. Previous research has reinforced the concept that gay men follow heterosexual masculinity and scripts in their relationships with other men. Here, analysing data from the most used gay dating app ‘Grindr’, we try to understand the balance among the different needs gay men in Italy express in their daily lives: from friendship to love, from casual sex to long-term relationships. Indeed, applying the heterosexual cultural script to gay men is problematic because hegemonic masculinity is also reinforced in …

Oral and Vaginal Epithelial Cell Lines Bind and Transfer Cell-Free Infectious HIV-1 to Permissive Cells but Are Not Productively Infected

2014

The majority of HIV-1 infections worldwide are acquired via mucosal surfaces. However, unlike the vaginal mucosa, the issue of whether the oral mucosa can act as a portal of entry for HIV-1 infection remains controversial. To address potential differences with regard to the fate of HIV-1 after exposure to oral and vaginal epithelium, we utilized two epithelial cell lines representative of buccal (TR146) and pharyngeal (FaDu) sites of the oral cavity and compared them with a cell line derived from vaginal epithelium (A431) in order to determine (i) HIV-1 receptor gene and protein expression, (ii) whether HIV-1 genome integration into epithelial cells occurs, (iii) whether productive viral in…

TEACHER OPINIONS ON SEXUAL EDUCATION OF STUDENTS WITH INTELLECTUAL DISABILITY IN LATVIA

2021

Sexual education plays an important role in preparing children and adolescents for a safe and productive life. Sex education provides not only knowledge about different types of sexual issues, or about common sexually transmitted diseases, unwanted pregnancies, sexual violence, but also personal identity, safety, love, intimacy and relationships.This study was conducted in order to examine the opinions of special education teachers working with adolescents with intellectual disabilities on sexual education. A descriptive study design was used. The authors designed a questionnaire to explore the opinions of 72 special education teachers in Latvia.The research results approved how crucial it …

Discovery of novel trichomonacidals using LDA-driven QSAR models and bond-based bilinear indices as molecular descriptors

2008

Few years ago, the World Health Organization estimated the number of adults with trichomoniasis at 170 million worldwide, more than the combined numbers for gonorrhea, syphilis, and chlamydia. To combat this sexually transmitted disease, Metronidazole (MTZ) has emerged, since 1959, as a powerful drug for the systematic treatment of infected patients. However, increasing resistance to MTZ, adverse effects associated to high-dose MTZ therapies and very expensive conventional technologies related to the development of new trichomonacidals necessitate novel computational methods that shorten the drug discovery pipeline. Therefore, bond-based bilinear indices, new 2-D bond-based TOMOCOMD-CARDD M…