Search results for "script"

showing 10 items of 5143 documents

Investigation of PTEN promoter methylation in ameloblastoma

2019

Background Phosphatase and tensin homolog (PTEN) acts as a tumor suppressor gene. Inactivation of PTEN has been reported in various types of cancers. PTEN promoter methylation possibly underlies PTEN inactivation, which results in tumorigenesis. The aim of this study was to investigate whether PTEN promoter methylation contributes to PTEN inactivation in ameloblastoma and its associated protein expression. Material and Methods In total, 20 fresh-frozen ameloblastoma samples were evaluated for PTEN promoter methylation using methylation-specific polymerase chain reaction (MS-PCR). A subset of 10 paraffin-embedded ameloblastoma samples was examined for PTEN expression through immunohistochemi…

Tumor suppressor genemedicine.disease_causePolymerase Chain ReactionAmeloblastoma03 medical and health sciences0302 clinical medicinemedicinePTENTensinHumansEpigeneticsAmeloblastomaPromoter Regions GeneticGeneral DentistryOral Medicine and PathologybiologyResearchPTEN Phosphohydrolase030206 dentistryDNA Methylationmedicine.disease:CIENCIAS MÉDICAS [UNESCO]ImmunohistochemistryReverse transcription polymerase chain reactionOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASDNA methylationbiology.proteinCancer researchSurgeryCarcinogenesis
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LaXp180, a mammalian ActA-binding protein, identified with the yeast two-hybrid system, co-localizes with intracellular Listeria monocytogenes

2001

The Listeria monocytogenes surface protein ActA is an important virulence factor required for listerial intracellular movement by inducing actin polymerization. The only host cell protein known that directly interacts with ActA is the phosphoprotein VASP, which binds to the central proline-rich repeat region of ActA. To identify additional ActA-binding proteins, we applied the yeast two-hybrid system to search for mouse proteins that interact with ActA. A mouse cDNA library was screened for ActA-interacting proteins (AIPs) using ActA from strain L. monocytogenes EGD as bait. Three different AIPs were identified, one of which was identical to the human protein LaXp180 (also called CC1). Bind…

Two-hybrid screeningImmunologyMolecular Sequence DataAutophagy-Related ProteinsFluorescent Antibody TechniqueStathminmacromolecular substancesmedicine.disease_causeMicrobiologylaw.inventionCell LineMicefluids and secretionsListeria monocytogenesBacterial ProteinslawVirologyTwo-Hybrid System TechniquesmedicineAnimalsHumansListeriosisAmino Acid SequencebiologyReverse Transcriptase Polymerase Chain ReactionBinding proteintechnology industry and agricultureIntracellular Signaling Peptides and ProteinsMembrane ProteinsProteinsListeria monocytogenesActinsBiochemistryPhosphoproteinembryonic structuresCOS CellsRecombinant DNAbiology.proteinbacteriaSignal transductionCarrier ProteinsIntracellularPlasmids
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Incidencia de factores personales y contextuales sobre el uso de los recursos tecnológicos por el alumnado en América Latina

2021

El uso de las tecnologías de la información y de la comunicación (TIC) por parte de alumnado refleja si el proceso de integración es apropiado. No obstante, la tipología de uso de las TIC en el alumnado no se ha establecido de forma empírica en función de su uso en casa y el centro educativo. Así, el propósito del artículo es determinar la estructura del uso de las TIC por parte del alumnado, junto con la influencia de factores personales y contextuales. Se ha empleado un diseño correlacional, siendo la muestra el alumnado de sexto curso de América Latina que ha respondido al cuestionario sobre uso de las TIC en el Tercer Estudio Regional Comparativo y Explicativo (TERCE). El análisis de da…

TypologyLatin AmericansDescriptive statisticsbusiness.industry05 social sciences050301 educationSample (statistics)EducationMultivariate analysis of varianceInformation and Communications TechnologyMathematics educationThe InternetbusinessPsychology0503 educationCategorical variableEducation Policy Analysis Archives
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From UML Specification into FPGA Implementation

2014

In the paper a method of using the Unified Modeling Language for specification of digital systems, especially logic controllers, is presented. The proposed method is based mainly on the UML state machine di- agrams and uses Hierarchical Concurrent Finite State Machines (HCFSMs) as a temporary model. The paper shows a way to transform the UML diagrams, expressed in XML language, to the form that is acceptable by reconfigurable FPGAs (Field Programmable Gate Ar- rays). The UML specification is used to generate an eective program in Hardware Description Languages (HDLs), especially Verilog.

UML toolFinite-state machineComputer scienceProgramming languageHardware description languageApplications of UMLlogic controllerscomputer.software_genreverilog.umlfpgaTK1-9971UML state machinefsmUnified Modeling LanguageVerilogElectrical engineering. Electronics. Nuclear engineeringElectrical and Electronic EngineeringcomputerObject Constraint Languagecomputer.programming_languageAdvances in Electrical and Electronic Engineering
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From UML State Machine Diagram into FPGA Implementation

2013

Abstract In the paper a method of using the Unified Modeling Language diagrams for specification of digital systems, especially logic controllers, is presented. The proposed method is based mainly on the UML state machine diagrams and uses Hierarchical Concurrent Finite State Machines (HCFSMs) as a temporary model. The paper shows a way to transform the UML diagrams to the form that is acceptable by reconfigurable FPGAs (Field Programmable Gate Arrays). The UML specification is used to generate an effective program in Hardware Description Languages (HDLs), especially Verilog.

UML toolFinite-state machineProgramming languageComputer scienceHardware description languageCommunication diagramApplications of UMLGeneral Medicinecomputer.software_genreUML state machineComputer Science::Hardware ArchitectureUnified Modeling LanguageSystems Modeling LanguageComputer Science::Programming LanguagesVerilogShlaer–Mellor methodClass diagramcomputercomputer.programming_languageObject Constraint LanguageIFAC Proceedings Volumes
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BioGRO: un nuveo método de alta resolución para el estudio de la transcripción naciente a escala genómica en levadura

2013

Esta tesis parte de la existencia de una técnica genómica para el estudio de la transcripción naciente en levadura ampliamente utilizada y contrastada: el Genomic run-on, basada en la utilización de macrochips de las ORFs completas del genoma de S. cerevisiae. Debido a la aparición progresiva de nuevas plataformas que permiten interrogar la totalidad de las regiones del genoma, y a una resolución mayor, como los microchips de embaldosado o tiling arrays, el objetivo principal de esta tesis es la puesta a punto de una técnica adaptada a ellas que permita un análisis detallado de la transcripción naciente. Los objetivos concretos que se marcaron fueron: -Desarrollar un nuevo procedimiento de …

UNESCO::CIENCIAS DE LA VIDAtranscriptómica:CIENCIAS DE LA VIDA [UNESCO]biología moleculargenética molecular de levaduras
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Soluciones bioinformáticas para el análisis de datos ómicos, descubrimiento de conocimiento y diagnóstico genético en Sparus aurata y otros organismo…

2023

Esta tesis ha sido financiada por el Ministerio de Ciencia e Innovación a través de la ayuda “DI-17-09134” para contratos para la formación de doctores en empresas (Doctorados Industriales). Con el incremento de datos generados mediante el uso de las tecnologías de secuenciación, es necesario el diseño de protocolos y herramientas que permitan el análisis y la integración de los mismos con el objetivo de entender y comprender los sistemas biológicos que forman parte de cada estudio en particular. Estas herramientas, además, es preferible que sean intuitivas y de fácil manejo para los usuarios, de manera que puedan ser utilizadas por cualquier investigador y no solamente por aquellos que sea…

UNESCO::CIENCIAS DE LA VIDA::Genética::Bioinformáticabioinformáticarna-seqhaplotipos víricosmicrobiotabiología de sistemasUNESCO::CIENCIAS DE LA VIDA::Genética::Genómica computacionaltranscriptómicaUNESCO::MATEMÁTICAS::Estadística ::Análisis de datosgenómicaUNESCO::MATEMÁTICAS::Ciencia de los ordenadores::Inteligencia artificialredes bayesianas
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Shaping women's agency through temporality in "The life and activity of the holy and blessed teacher Syncletica"

2020

The present article attempts to discuss the relationship between two female characters, Thecla and Syncletica, against the wider theoretical background of temporality as it was perceived and construed through literary texts. Syncletica is portrayed as a ‘disciple’ of Thecla. However, while the apocryphal Acts of Paul and Thecla appear to be pervaded with an eschatological expectation, the Life of Saint Syncletica shows signs of a different temporality. The detailed description of the whole life of Syncletica, with an emphasis on the course of illness, reveals a temporality more focused on the stages of life. Building on this evidence, I aim to identify a set of key features that…

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRAS1135-9560 8276 Studia philologica valentina 567083 2020 22 7762311 Shaping women?s agency through temporality in The life and activity of the holy and blessed teacher Syncletica Dell'IsolaI aim to identify a set of key features that may define the influence of different notions of time on two women saints closely related to each other. 13 31reveals a temporality more focused on the stages of life. Building on this evidence:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]with an emphasis on the course of illnessThecla and SyncleticaMaria The present article attempts to discuss the relationship between two female characterswhile the apocryphal Acts of Paul and Thecla appear to be pervaded with an eschatological expectationagainst the wider theoretical background of temporality as it was perceived and construed through literary texts. Syncletica is portrayed as a ?disciple? of Thecla. Howeverthe Life of Saint Syncletica shows signs of a different temporality. The detailed description of the whole life of Syncletica
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Conocimiento acerca de las estrategias de práctica instrumental al inicio del Grado Superior de Música

2017

Cabe pensar que un estudiante de instrumento que accede al Grado Superior de Música, tras aproximadamente 10 años de formación, debería tener una práctica efectiva y, por lo tanto, un manejo adecuado de numerosas estrategias. En este sentido, el estudio se planteó con objeto de corroborar el estado de conocimientos previos de los estudiantes que ingresan al Conservatorio Superior de Música de Aragón con respecto a diversas estrategias de práctica instrumental de eficacia avalada por investigaciones previas y/o la experiencia profesional de grandes intérpretes. La investigación de carácter descriptivo presenta una metodología de carácter cualitativo en la que las técnicas de recogida de dato…

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASDidácticas aplicadasData collection010102 general mathematics0102 computer and information sciencescomputer.software_genre01 natural sciencesEducationIndividual study010201 computation theory & mathematics:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]PedagogyPsicología y educaciónArte0101 mathematicsDescriptive researchPersonal interviewPsychologycomputerMusicInterpreterMúsicaQualitative researchRevista Electrónica de LEEME
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El Llibre de menescalia de la Societat Castellonenca de Cultura

2017

The library of the Societat Castellonenca de Cultura (Castello de la Plana) keeps a Catalan manuscript on menescalia  (veterinary medicine) virtually unknown to the specialists. Here we provide a diplomatic description, a presentation of its content, and particularly a first linguistic analysis. Our study allows us to locate its elaboration in the mid-14th century within the area of Morella, and to attribute it to a paraire or to a merchant. The manuscript is currently in the process of being edited.

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASHistoryHistoryLiterature and Literary Theorymedia_common.quotation_subjectlanguage.human_languagePresentationLinguistic analysisveterinary medicine; medieval manuscripts; Old Catalan texts; Morella; linguistic study:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]languageCatalanHumanitiesElaborationmedia_commonMagnificat Cultura i Literatura Medievals
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