Search results for "script"
showing 10 items of 5143 documents
Resumen tradicional o resumen estructurado, o cómo persuadir al lector
2015
En este artículo se estudia el resumen tradicional y estructurado al objeto de valorar su contenido a través de sus cinco unidades informativas, así como la presencia de información adicional en la unidad 'métodos', para poder determinar el modelo de resumen que mejor persuada al lector. La investigación se desarrolla a partir de un corpus de 320 resúmenes de revistas españolas de enfermería. Entre los resultados más significativos destaca su variabilidad estructural, siendo mayor la información en el resumen estructurado y, como consecuencia, mayor el tamaño del mismo. A partir de estos resultados se puede concluir que hace falta incidir en la necesidad de unificar criterios para una mejor…
Sp1 transcription factor interaction with accumulated prelamin a impairs adipose lineage differentiation in human mesenchymal stem cells: essential r…
2012
Abstract Lamin A (LMNA)-linked lipodystrophies may be either genetic (associated with LMNA mutations) or acquired (associated with the use of human immunodeficiency virus protease inhibitors [PIs]), and in both cases they share clinical features such as anomalous distribution of body fat or generalized loss of adipose tissue, metabolic alterations, and early cardiovascular complications. Both LMNA-linked lipodystrophies are characterized by the accumulation of the lamin A precursor prelamin A. The pathological mechanism by which prelamin A accumulation induces the lipodystrophy associated phenotypes remains unclear. Since the affected tissues in these disorders are of mesenchymal origin, we…
GLI3 is rarely implicated in OFD syndromes with midline abnormalities
2011
A range of phenotypes including Greig cephalopolysyndactyly and Pallister-Hall syndromes (GCPS, PHS) are caused by pathogenic mutation of the GLI3 gene. To characterize the clinical variability of GLI3 mutations, we present a subset of a cohort of 174 probands referred for GLI3 analysis. Eighty-one probands with typical GCPS or PHS were previously reported, and we report the remaining ninety-three probands here. This includes nineteen probands (twelve mutations) who fulfilled clinical criteria for GCPS or PHS, forty-eight probands (sixteen mutations) with features of GCPS or PHS but who did not meet the clinical criteria (sub-GCPS and sub-PHS), twenty-one probands (six mutations) with featu…
Bleomycin, a selective inhibitor of DNA-dependent DNA polymerase from oncogenic RNA viruses.
1972
Abstract Bleomycin, an antibiotic, inhibits the DNA-dependent DNA polymerase from Rauscher murine leukemia virus. Higher concentrations of BLM ∗ are required to inhibit it's RNA-dependent DNA polymerase. These inhibition effects of the non-competitive type are not altered by preincubation of the DNA with BLM. Under comparable conditions neither the DNA-dependent DNA polymerase activity from E. coli and mouse liver nor the DNA-dependent RNA polymerase activity from mouse lymphoma cells are affected by BLM.
Bleomycin: Action on growth of oncogenic RNA viruses and on cell transformation
1975
Bleomycin (BLM) inhibits cell proliferation of noninfected chick embryo fibroblasts by blocking their DNA synthesis selectively. Chick embryo fibroblasts have beentransformed by Schmidt-Ruppin D strain of Rous Sarcoma Virus. Transformation has been determined by a focus assay. Foci formation is strongly reduced by BLM. Virus replication is inhibited by BLM in growing and confluent monolayer cells. This result might be explained by the observation that this drug reduces proliferation of growing and of confluent monolayer cells very sensitively. During the first 24 hours after infection the BLM inhibitory effect is more pronounced than in the case of BLM-application during the period 24--48 h…
Evidence of oxidative stress in very long chain fatty acid--treated oligodendrocytes and potentialization of ROS production using RNA interference-di…
2011
X-linked adrenoleukodystrophy (X-ALD) and pseudo neonatal adrenoleukodystrophy (P-NALD) are neurodegenerative demyelinating diseases resulting from the functional loss of the peroxisomal ATP-binding cassette transporter D (ABCD1) and from single peroxisomal enzyme deficiency (Acyl-CoA oxidase1: ACOX1), respectively. As these proteins are involved in the catabolism of very long chain fatty acids (VLCFA: C24:0, C26:0), X-ALD and P-NALD patients are characterized by the accumulation of VLCFA in plasma and tissues. Since peroxisomes are involved in the metabolism of reactive oxygen species (ROS) and nitrogen species (RNS), we examined the impact of VLCFA on the oxidative status of 158N murine o…
The Copper-microRNA Pathway Is Integrated with Developmental and Environmental Stress Responses in Arabidopsis thaliana
2021
As an essential nutrient, copper (Cu) scarcity causes a decrease in agricultural production. Cu deficiency responses include the induction of several microRNAs, known as Cu-miRNAs, which are responsible for degrading mRNAs from abundant and dispensable cuproproteins to economize copper when scarce. Cu-miRNAs, such as miR398 and miR408 are conserved, as well as the signal transduction pathway to induce them under Cu deficiency. The Arabidopsis thaliana SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE (SPL) family member SPL7 binds to the cis-regulatory motifs present in the promoter regions of genes expressed under Cu deficiency, including Cu-miRNAs. The expression of several other SPL transcription f…
Produire expérimentalement des corpus spécialisés pour l’analyse sémantique : méthodes et enjeux
2018
International audience; [Contexte] La présente proposition vise, à la suite de De Mönnink (1999) et Gilquin / Gries (2009), à interroger et discuter le rôle de corpus produits expérimentalement et de façon ad hoc pour l’analyse du lexique spécialisé – que les unités considérées soient officiellement reconnues comme termes ou non. Elle s’inscrit dans le paradigme d’une recherche située (Condamines / Narcy-Combes 2015) et intrinsèquement interdisciplinaire (Gautier 2014). Si les corpus spécialisés écrits, et dans une moindre mesure oraux, sont devenus monnaie courante, qu’ils soient intégrés aux corpus de référence ou produits pour des besoins spécifiques (Loock 2016), les corpus expérimentau…
Rescritto degli imperatori Diocleziano e Massimiano sulla longi temporis praescriptio
2012
L'a. analizza un papiro recante un rescritto degli imperatori Diocleziano e Massimiano relativo probabilmente alla longi temporis praescriptio.
Introduction. Into the Translation for Museums, Festivals, and the Stage: Creativity and the Transmedial Turn
2022
With the objective of scrutinising general standards, specific criteria and levels of creativity applied to translation practices, especially in light of recent research in audiovisual consumption and reception, creativity and transcreation, and arts accessibility and translation for the arts, the special issue seeks to contextualise the numerous shifts within the artisitc sector in relation to the theoretical and practical challenges that our increasingly technological culture poses for the modes of translation and accessibility. Contributors shed light upon a variety of cultural areas where translation, often combined with creativity, intervenes to localise aesthetic products under the ne…