Search results for "selection"
showing 10 items of 1940 documents
Pharmacogenetics of treatments for pancreatic cancer
2019
Introduction: Despite clinical efforts, pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The scarcity of effective therapies can be reflected by the lack of reliable biomarkers to adapt anticancer drugs prescription to tumors’ and patients’ features. Areas covered: Pharmacogenetics should provide the way to select patients who may benefit from a specific therapy that best matches individual and tumor genetic profile, but it has not yet led to gains in outcome. This review describes PDAC pharmacogenetics findings, critically reappraising studies on polymorphisms and -omics profiles correlated to response to gemcitabine, FOLFIRINOX, and nab-paclitaxel combinations, as well as l…
Transplantation in follicular lymphoma: not "yes or no" but "whom and when".
2013
After years of debate, the question as to what is the optimal use of transplantation strategies in indolent lymphoma remains controversial. In the July issue of Haematologica, a study was published by the EBMT Lymphoma Working Party that aims to define indications for hematopoietic stem cell
Traitement 3D de nuages de points basé sur la connaissance
2013
The modeling of real-world scenes through capturing 3D digital data has proven to be both useful andapplicable in a variety of industrial and surveying applications. Entire scenes are generally capturedby laser scanners and represented by large unorganized point clouds possibly along with additionalphotogrammetric data. A typical challenge in processing such point clouds and data lies in detectingand classifying objects that are present in the scene. In addition to the presence of noise, occlusionsand missing data, such tasks are often hindered by the irregularity of the capturing conditions bothwithin the same dataset and from one data set to another. Given the complexity of the underlying…
Ontological information system for the selection of technologies for the treatment and disposal of organic waste: engineering and educational aspects
2021
The article proves a problem of information processing in the field of the structuring of information and decision-making in environmental engineering, including education in this field. This article presents the ontology-information model that was used to systematize waste treatment equipment. The article presents the use of an ontological algorithm “Polyhedron” for engineers and teachers. The algorithm consists of integrating ontological solutions from abstract to specific. The proposed model consists of a general ontology of “waste treatment technologies selection”, “waste treatment equipment selection” and “Ontology for the analysis of scientific publications”. Users of the system can i…
Project Selection by Constrained Fuzzy AHP
2004
The selection of a project among a set of possible alternatives is a difficult task decision makers have to face. Difficulties in selecting a project arise because of the different goals involved and because of the large number of attributes to consider. Our approach is based upon a fuzzy extension of the Analytic Hierarchy Process (AHP). This paper focuses on the constraints that have to be considered within fuzzy AHP in order to take in account all the available information. This study demonstrates that by considering all the information deriving from the constraints better results in terms of certainty and reliability can be achieved.
A fast algorithm for muon track reconstruction and its application to the ANTARES neutrino telescope.
2011
An algorithm is presented, that provides a fast and robust reconstruction of neutrino induced upward-going muons and a discrimination of these events from downward-going atmospheric muon background in data collected by the ANTARES neutrino telescope. The algorithm consists of a hit merging and hit selection procedure followed by fitting steps for a track hypothesis and a point-like light source. It is particularly well-suited for real time applications such as online monitoring and fast triggering of optical follow-up observations for multi-messenger studies. The performance of the algorithm is evaluated with Monte Carlo simulations and various distributions are compared with that obtained …
Joint Power Allocation and Link Selection for Multi-Carrier Buffer Aided Relay Network
2019
In this paper, we present a joint power allocation and adaptive link selection protocol for an orthogonal frequency division multiplexing (OFDM)-based network consists of one source node i.e., base station (BS), one destination node i.e., (MU) and a buffer aided decode and forward (DF) relay node. Our objective is to maximize the average throughput of the system via power loading over different subcarriers at source and relay nodes. A separate power budget is assumed at each transmitting node to make the system more practical. In order to form our solution more tractable, a decomposition framework is implemented to solve the mixed integer optimization problem. Further, less complex suboptim…
Distributed Resource Allocation for Energy Efficiency in OFDMA Multicell Networks with Wireless Power Transfer
2019
In this paper, an energy-efficient resource allocation problem is investigated for the wireless power transfer (WPT)-enabled OFDMA multicell networks. In the considered system, multiple base stations (BSs) with a large number of antennas are responsible to provide WPT in the downlink, and the users can recycle and utilize the received energy for uplink data transmission. The role of BS is to execute WPT; thus, there are no data transmissions in the downlink. A time-division protocol is considered to divide the time of downlink WPT and uplink wireless information transfer into separate time slots. With the objective to improve the energy efficiency, we propose the time, subcarrier, and power…
Multicriteria-Oriented Optimization of Building Energy Performances: The Annex 72 IEA-EBC Experience
2021
International audience; This chapter describes the research experience of the International Energy Agency-Energy in Buildings and Communities Programme Annex 72 members on the application of multi-objective optimization processes for the selection of design or retrofit actions that allow for improving different aspects (energy, environmental, economic, etc.) of buildings in a life cycle perspective. Thirteen case studies were examined focussing on methodologies, applications and results and deriving generic conclusions and guidelines for building designers and decision-makers.
Multi Sources Water Supply System Optimal Control: A Case Study
2014
The optimal operation of a multi quality network was analysed applying Linear Programming methods. The peculiar service condition of the industrial city of Gela (Italy) was investigated. The network is supplied both from waters derived from a desalination plant and other natural sources. The method aimed to minimise energy cost and find the optimal operation control, while satisfying demand and quality constraints, specifically with regard to water temperature. The method proved to be effective in the selection of the optimal management strategy after the definition of a specific water quality target. (C) 2014 Published by Elsevier Ltd.