Search results for "self-condensation"

showing 2 items of 12 documents

A new synthesis of soluble poly(1,4-phenylenevinylene)s and poly(2,5-pyrimidinylenevinylene)s

1991

Abstract Alkoxy-substituted 4-methylbenzylideneanilines 2a-f and their pyrimidine analogues 2g,h show an efficient selfcondensation in the alkaline medium KOC(CH 3 ) 3 /DMF. The totally stereoselective reaction yields 3a-h which are transformed by acidic work-up to 4a-h . A narrow distribution of the molecular weight can be achieved.

chemistry.chemical_classificationPyrimidine analoguechemistryOrganic ChemistryDrug DiscoveryPolymer chemistryOrganic chemistryStereoselectivityPolymerSelf-condensationBiochemistryTetrahedron Letters
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Synthesis of 6,12-Disubstituted Methanodibenzo[b,f][1,5]dioxocins : Pyrrolidine Catalyzed Self-Condensation of 2′-Hydroxyacetophenones

2019

The preparation of unprecedented 6,12-disubstituted methanodibenzo[b,f][1,5]dioxocins from pyrrolidine catalyzed self-condensation of 2′-hydroxyacetophenones is herein described. This method provides easy access to this highly bridged complex core, resulting in construction of two C–O and two C–C bonds, a methylene bridge and two quaternary centers in a single step. The intricate methanodibenzo[b,f][1,5]dioxocin compounds were obtained in up to moderate yields after optimization of the reaction conditions concerning solvent, reaction times and the use of additives. Several halide substituted methanodibenzo[b,f][1,5]dioxocins could be prepared from correspondent 2′-hydroxyacetophenones.

lcsh:QD241-441kemiallinen synteesiself-condensationlcsh:Organic chemistryenamine116 Chemical sciences15-dioxocin2′-hydroxyacetophenoneorgaaniset yhdisteet
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