Search results for "semina"

Our aim is to transfer life-saving knowledge to large numbers of responders: Knowledge Dissemination in the E-health Era

2020

The origin of ‘public health’ discourse goes back to the 19th century when ideas of health and wellness began to take hold as an academic discipline at universities first in Europe (France and UK), and then in US. As scientific knowledge grew, public authorities were more concerned on general sanitation (Chave 1984) and gradually were formed to employ newly discovered interventions against health threats. The principles of public health in earlier times were guided more by the notions of the commons, wellbeing, and local knowledge. In recent times, our understanding and practice of public health is guided more by technological advances generally based on governmental decisions (Green et. al…

Maaseutupappilat tyttöjä jatko-opintoihin valmistaneina kotikouluina

2023

Effect Declines Are Systematic, Strong, and Ubiquitous: A Meta-Meta-Analysis of the Decline Effect in Intelligence Research

2019

Empirical sciences in general and psychological science in particular are plagued by replicability problems and biased published effect sizes. Although dissemination bias-related phenomena such as publication bias, time-lag bias, or visibility bias are well-known and have been intensively studied, another variant of effect distorting mechanisms, so-called decline effects, have not. Conceptually, decline effects are rooted in low initial (exploratory) study power due to strategic researcher behavior and can be expected to yield overproportional effect declines. Although decline effects have been documented in individual meta-analytic investigations, systematic evidence for decline effects in…

The C-terminal antibody binding domain ofCandida albicansmp58 represents a protective epitope during candidiasis

2003

The 58-kDa surface mannoprotein of Candida albicans (mp58) elicits strong antibody responses during infection. Epitope mapping with sera from patients with candidiasis and control individuals indicated the presence of multiple IgG-reactive continuous epitopes on the protein, expanding both the amino- and carboxy-terminal domains and several internal regions. These immunoreactive regions were similar to the ones previously identified using sera from immunized animals. Two of the epitopic regions (including the C-terminal domain) showed increased reactivity with antibodies present in sera from patients with candidiasis as compared to control individuals. Patients who survived the infection di…

Improving Oral–Systemic Healthcare through the Interoperability of Electronic Medical and Dental Records: An Exploratory Study

2019

Objectives Electronic health records (EHRs) are rarely shared among medical and dental providers. The purpose of this study was to assess current information sharing and the value of improved electronic information sharing among physicians and dentists in Germany and the United States. Materials and Methods A survey was validated and distributed electronically to physicians and dentists at four academic medical centers. Respondents were asked anonymously about EHR use and the medical and dental information most valuable to their practice. Results There were 118 responses, a response rate of 23.2%. The majority (63.9%) of respondents were dentists and the remainder were physicians. Most res…

Communal data work: Data sharing and re-use in clinical genetics

2019

In this article, we examine work with communal data in the context of clinical genetic testing. Drawing from prior research on digital research infrastructures and from the analysis of our empirical data on genetic testing, we describe how data generated in laboratories distributed all over the world are shared and re-used. Our research findings point to six different human-driven activities related to expanding, disambiguating, sanitizing and assessing the relevance, validity and combinability of data. We contribute to research within Health Informatics with a framework that foregrounds human-driven activities for data interoperability.

Fresh cell therapy followed by fatal coma

1986

A 60-year-old woman received a 3-day course of nine injections of “fresh” cells from fetal lamb ovary, placenta, brain (hypothalamus) and liver. There were no immediate complications, but a few days later she developed headache, fever and hemiparesis. She subsequently fell into a coma and died 3 weeks after her fresh cell therapy and 2 weeks after the onset of her clinical symptoms. Autopsy revealed perivenous leucoencephalopathy with a probably steroid-treatment-induced paucity of perivascular inflammation. Fresh cell therapy, clinical symptomatology and morphological findings suggest, though do not prove, that this patient's monophasic and probably immune-mediated disease is a rare and fa…

Spinal Intradural Intramedullary Dissemination in the Absence of Intracranial Relapse of a Previously Radically Treated Temporal Lobe Glioblastoma Mu…

2017

Intracranial glioblastoma multiforme (GBM) constitutes the most frequent and unfortunately aggressive primary central nervous system malignancy. Despite the high tendency of these tumors to show local relapse within the brain after primary therapy, dissemination into the spinal axis is an infrequent event. If spinal metastases occur they are leptomeningeal in the vast majority of cases and always in the context of intracranial progressive disease. Spinal intramedullary metastases of intracranial GBM have rarely been described to date. We report the unique case of a young woman with subacute progressive paraparesis due to spinal intramedullary metastases of a temporal lobe GBM despite the re…

Connection between body condition score, chemical characteristics of body and reproductive traits of rabbit does.

2008

Abstract Body condition scoring (BCS) is widely used to evaluate the nutritional status of livestock (cows, ewes, sows). In intensive systems, rabbit does are generally inseminated 11 days post partum and, due to a hormonal antagonism and an energy deficit caused by concurrent lactation and pregnancy, they show low fertility. The aim of this investigation was to assess an in vivo method for scoring the body condition of does by verifying the association with the body fat depots, the chemical composition of body tissues, the ovarian status, the hormonal response and the reproductive performance. The evaluation of BCS, involving 66 multiparous lactating does inseminated at 11 days post partum…

Additive effect of factors related to assisted conception on the reduction of maternal serum pregnancy-associated plasma protein A concentrations and…

2013

Objective To analyze whether assisted conceptions need adjustments in first-trimester Down syndrome screening and why modifications in screening markers occur. Design Eleven-year cohort retrospective analysis. Setting Maternal-fetal medicine unit. Patient(s) Two thousand eleven naturally conceived normal singleton pregnancies and 2,042 normal singleton pregnancies achieved with assisted conception: 350 by IUI and 1,692 with IVF (n = 328) or intracytoplasmic sperm injection (ICSI; n=1,364), using nondonor (n = 1,086) or donated ova (n = 606), with fresh (n = 1,432) or frozen (n = 260) embryos. Intervention(s) Comparison of ultrasound and biochemical markers of first-trimester Down syndrome s…