Search results for "sensitive"
showing 10 items of 210 documents
Reflux reactions for chromatography
1976
Reactions under pressure are mainly used to prepare derivatives before chromatographic analysis because of the lack of microequipment. A ml-refluxer has been designed to allow reactions under atmospheric pressure for volumes from 0.2 to 5 cm3. The reaction temperature is determined by the boiling point of the solvent thus derivatives of heat sensitive compounds can be made in the micro scale. With the aid of the ml-refluxer large series of derivatisations can be carried out and hence the reaction parameters can be optimized. This is shown at the example of the alkylation of barbituric acids for gas chromatography, where thus only N,N′-derivatives were obtained. The reliability of the appara…
Vesicle transport and photoreceptor death: fishing for molecular links.
2013
Intracellular vesicle transport defects can induce retinal degeneration and photoreceptor cell death, but the molecular connections between these processes remains poorly understood. Reporting in Developmental Cell, Nishiwaki et al. (2013) suggest that a vesicle fusion cis-SNARE complex component translates vesicular transport defects into photoreceptor cell apoptosis.
Participants’ home as an interview context when studying sensitive family issues
2013
This article considers the meaning of the participants’ home as an interview context when studying sensitive family issues. The article is based on two qualitative family studies by the authors on foster children’s perspectives on their home and their family relations and client families’ experiences of preventive family support. Both studies address sensitive family issues, in particular Finnish child welfare. The first author’s interview data consist of interviews with foster children, social network maps and diaries and the second author’s data of interviews with six client families. Most of the interviews were conducted at the participants’ homes, but in the second author's study two in…
From top-down urban planning to culturally sensitive planning? Urban renewal and artistic activism in a neo-bohemian district in Barcelona
2020
The city of Barcelona in general and its historic center in particular have undergone a sea change from an industrial city to a global tourism and service center. Some authors argue that urban rene...
Quantifying Mean Shape and Variability of Footprints Using Mean Sets
2005
This paper1 presents an application of several definitions of a mean set for use in footwear design. For a given size, footprint pressure images corresponding to different individuals constitute our raw data. Appropriate footwear design needs to have knowledge of some kind of typical footprint. Former methods based on contour relevant points are highly sensitive to contour noise; moreover, they lack repeatability because of the need for the intervention of human designers. The method proposed in this paper is based on using mean sets on the thresholded images of the pressure footprints. Three definitions are used, two of them from Vorob’ev and Baddeley-Molchanov and one morphological mean p…
Metilazione del DNA in artrite reumatoide
2005
Lo stato di metilazione del DNA genomico e del gene PTHrP è stato valutato con tecniche molecolari e citogenetiche in artrite reumatoide (AR), patologia autoimmune caratterizzata anche da alta incidenza di linfomi e da ipercalcemia per overespressione del gene PTHrP. La metilazione del DNA, infatti, ha un ruolo critico nello sviluppo delle malattie neoplastiche; il gene PTHrP avendo tre promotori uno dei quali contiene un’isola CpG è un buon candidato per la deregolazione da alterato pattern di metilazione locale. Le indagini sulla metilazione genomica, condotte su DNA estratto da sangue periferico di pazienti e di donatori e amplificato in reazioni di Methylation-Sensitive Arbitrarily Prim…
The role of natural complexity in adaptive architecture : Eco-based design: Nature as pattern and architecture element
2021
In the broader context of an ongoing doctoral research, it is possible to consider adaptive architecture as a possible solution for designing resilience. Despite the large use of technology, it is possible in fact to recognise different design approaches that involve Nature in the whole process, from the initial conceptual phase toward the effective construction stage. Among these different ways, which underline a biomorphic common perspective, this paper would focus on two of them, underlying the role of nature in the design approach. The first is referred to the consideration of Nature as a design material and is shown through the projects of the American architectural firm SCAPE, ‘Living…
NUOVE FRONTIERE MUSEOGRAFICHE : immaterialità e multimedialità del museo narrativo
2021
Il contributo esplora, anche attraverso la lettura di alcuni casi studio, gli aspetti costitutivi e connotativi di ciò che può essere definita la nuova ‘frontiera della museografia’. Una ‘frontiera’ riconoscibile nella definizione di museo strutturato secondo il concetto ‘dell’allestimento integrato’ che si basa, prevalentemente, sul connubio tra strumentazioni tecnologiche avanzate, arte e interattività dei sistemi divulgativi dei contenuti museografici. In questi ultimi anni sono state sviluppate diverse esperienze museali caratterizzate da indagini sui nuovi linguaggi tecnologici, ma che non tralasciano la fondamentale elaborazione di scopi e contenuti degli stessi progetti allestitivi c…
An Efficient Retransmission Strategy for Data Gathering in Wireless Sensor Networks Authors
2005
This paper introduces a new strategy for data gathering in wireless sensor networks that takes into account the need for both energy saving and for a reasonable tradeoff between robustness and efficiency. The proposed algorithm implements an efficient strategy for retransmission of lost packets by discovering alternative routes and making clever use of multiple paths when necessary; in order to do that we use duplicate and order insensitive aggregation functions, and by taking advantage of some intrinsic characteristics of the wireless sensor networks, we exploit implicit acknowledgment of reception and smart caching of the data.
Fiat lux: the light became therapy. An overview on the Bright Light Therapy in Alzheimer’s Disease sleep disorders
2020
Background: A system of photosensitive retinal ganglion cells provides ‘non-visual’ information on the circadian sequences of light to the suprachiasmatic nucleus (SCN), which, as the ‘master clock’, synchronizes the chronobiological mechanisms of all the biological clocks. Damage to SCN structure alters circadian behavioral and hormonal rhythms and interferes with a regular sleep-wake pattern. Several studies have shown that, in aging and in Alzheimer’s disease (AD), circadian rhythms change their synchronization with the environment and behavior loses sync with light. Objective: The current overview aims to examine research studies showing the effect of bright light therapy (BLT) on sleep…