Search results for "sensorimotor cortex"

Cortical gene expression in spinal cord injury and repair: insight into the functional complexity of the neural regeneration program

2011

Traumatic spinal cord injury (SCI) results in the formation of a fibrous scar acting as a growth barrier for regenerating axons at the lesion site. We have previously shown (Klapka et al., 2005) that transient suppression of the inhibitory lesion scar in rat spinal cord leads to long distance axon regeneration, retrograde rescue of axotomized cortical motoneurons, and improvement of locomotor function. Here we applied a systemic approach to investigate for the first time specific and dynamic alterations in the cortical gene expression profile following both thoracic SCI and regeneration-promoting anti-scarring treatment (AST). In order to monitor cortical gene expression we carried out micr…

More comprehensive proprioceptive stimulation of the hand amplifies its cortical processing

2021

Corticokinematic coherence (CKC) quantifies the phase coupling between limb kinematics and cortical neurophysiological signals reflecting proprioceptive feedback to the primary sensorimotor (SM1) cortex. We studied whether the CKC strength or cortical source location differs between proprioceptive stimulation (i.e., actuator-evoked movements) of right-hand digits (index, middle, ring, and little). Twenty-one volunteers participated in magnetoencephalography measurements during which three conditions were tested: 1) simultaneous stimulation of all four fingers at the same frequency, 2) stimulation of each finger separately at the same frequency, and 3) simultaneous stimulation of the fingers…

Identification of proprioceptive thalamocortical tracts in children: comparison of fMRI, MEG, and manual seeding of probabilistic tractography

2022

Publisher Copyright: © The Author(s) 2022. Published by Oxford University Press. Studying white matter connections with tractography is a promising approach to understand the development of different brain processes, such as proprioception. An emerging method is to use functional brain imaging to select the cortical seed points for tractography, which is considered to improve the functional relevance and validity of the studied connections. However, it is unknown whether different functional seeding methods affect the spatial and microstructural properties of the given white matter connection. Here, we compared functional magnetic resonance imaging, magnetoencephalography, and manual seedin…

Attention directed to proprioceptive stimulation alters its cortical processing in the primary sensorimotor cortex.

2021

Funding Information: This study has been supported by the Academy of Finland ”Brain changes across the life‐span” profiling funding to University of Jyväskylä (grant #311877). HP was supported by Academy of Finland (grants #296240, #326988, #307250 and #327288) to HP and Jane and Aatos Erkko Foundation (grant #602.274). Publisher Copyright: © 2021 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd. Copyright: Copyright 2021 Elsevier B.V., All rights reserved. Movement-evoked fields to passive movements and corticokinematic coherence between limb kinematics and magnetoencephalographic signals can both be used to …

Joint damage and motor learning during unipedal stance in haemophilia arthropathy: report of two cases

2016

Proprioceptive response strength in the primary sensorimotor cortex is invariant to the range of finger movement

2023

Available online 13 February 2023 Proprioception is the sense of body position and movement that relies on afference from the proprioceptors in muscles and joints. Proprioceptive responses in the primary sensorimotor (SM1) cortex can be elicited by stim- ulating the proprioceptors using evoked (passive) limb movements. In magnetoencephalography (MEG), propri- oceptive processing can be quantified by recording the movement evoked fields (MEFs) and movement-induced beta power modulations or by computing corticokinematic coherence (CKC) between the limb kinematics and cortical activity. We examined whether cortical proprioceptive processing quantified with MEF peak strength, relative beta supp…