Search results for "sequence"
showing 10 items of 4987 documents
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
2011
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. Common sequence variants have recently joined rare structural polymorphisms as genetic factors with strong evidence for association with schizophrenia. Here we extend our previous genome-wide association study and meta-analysis (totalling 7 946 cases and 19 036 controls) by examining an expanded set of variants using an enlarged follow-up sample (up to 10 260 cases and 23 500 controls). In addition to previously reported alleles in the major histocompatibility complex region, near neurogranin (NRGN) and in an intron of transcription factor 4 (TCF4), we find two novel variants show…
Nuevas faunas de micromamíferos del Terciario continental de la Depresión Intermedia (provincia de Cuenca, España centro-oriental)
1986
In this paper the fossil content of nine new micromammal bearing localities and that of 15 levels in a borehole from the Loranca Basin (eastern Tague Basin, Prov. of Cuenca) is described. The age ranges from early Arvernian (Late Oligocene) to Turolian (Late Miocene). 47 rodent and lagomorph taxons have been found which are arranged in 8 biostratigraphic units. The Loranca-2 borehole contains 15 fossiliferous levels covering the Upper Oligocene/Lower Miocene. These additional data complete the faunal sequence published by Díaz & López(1919). The stratigraphic framework of the basin needs a revision because of the new faunal data.<br><br>Se presenta una serie de 9 nuevos yaci…
Lingüística perceptiva y conversación: secuencias
1993
Se presenta la organización de las secuencias conversacionales a partir del modelo teórico de la lingüística cognitiva-perceptiva. Junto a a las secuencias de apertura y cierre conversacional (Secuencias marco), los cuatro niveles identificados por la teoría perceptiva (rección, concordancia, orden y énfasis) permiten identificar cuatro tipos fundamentales de secuencia conversacional (secuencias de historia, de concordancia, lineales y de inserción).
Dimmi che sigla guardi e ti dirò chi sei
2020
Opening credits, sequences which accompany each episode of a television series, have radically changed over time. From being brief and marginal texts, edited with low care e watched with a low level of attention, they have become artistic and elegant sequences, often created by specialized companies to keep the viewer’s eyes glued to the screen. The opening credits still keep their original function – giving information about the programme – but nowadays they achieve their goal in various ways. The main titles refer to the content of the series using different tones, thereby setting a particular mood that prepares the viewer for the show. In this article, we will try to focus on these diffe…
From Sequences to Variables : Rethinking the Relationship between Sequences and Outcomes
2021
Sequence analysis is increasingly used in the social sciences for the holistic analysis of life-course and other longitudinal data. The usual approach is to construct sequences, calculate dissimilarities, group similar sequences with cluster analysis, and use cluster membership as a dependent or independent variable in a regression model. This approach may be problematic, as cluster memberships are assumed to be fixed known characteristics of the subjects in subsequent analyses. Furthermore, it is often more reasonable to assume that individual sequences are mixtures of multiple ideal types rather than equal members of some group. Failing to account for uncertain and mixed memberships may l…
Some Investigations on Similarity Measures Based on Absent Words
2019
In this paper we investigate similarity measures based on minimal absent words, introduced by Chairungsee and Crochemore in [1]. They make use of a length-weighted index on a sample set corresponding to the symmetric difference M(x)ΔM(y) of the minimal absent words M(x) and M(y) of two sequences x and y, respectively. We first propose a variant of this measure by choosing as a sample set a proper subset (x, y) of M(x)ΔM(y), which appears to be more appropriate for distinguishing x and y. From the algebraic point of view, we prove that (x, y) is the base of the ideal generated by M(x)ΔM(y). We then remark that such measures are able to recognize whether the sequences x and y share a common s…
Functional Information, Biomolecular Messages and Complexity of BioSequences and Structures
2010
In the quest for a mathematical measure able to capture and shed light on the dual notions of information and complexity in biosequences, Hazen et al. have introduced the notion of Functional Information (FI for short). It is also the result of earlier considerations and findings by Szostak and Carothers et al. Based on the experiments by Charoters et al., regarding FI in RNA binding activities, we decided to study the relation existing between FI and classic measures of complexity applied on protein-DNA interactions on a genome-wide scale. Using classic complexity measures, i.e, Shannon entropy and Kolmogorov Complexity as both estimated by data compression, we found that FI applied to pro…
A Process-Oriented View of Procedural Memory Can Help Better Understand Tourette’s Syndrome
2021
Tourette’s syndrome (TS) is a neurodevelopmental disorder characterized by repetitive movements and vocalizations, also known as tics. The phenomenology of tics and the underlying neurobiology of the disorder have suggested that the altered functioning of the procedural memory system might contribute to its etiology. However, contrary to the robust findings of impaired procedural memory in neurodevelopmental disorders of language, results from TS have been somewhat mixed. We review the previous studies in the field and note that they have reported normal, impaired, and even enhanced procedural performance. These mixed findings may be at least partially be explained by the diversity of the s…
Contribución al conocimiento de la secuencia arqueológica y el hábitat del Holoceno inicial en el Maestrazgo
2006
Se presenta el estudio de un total de cinco yacimientos localizados en el tramo superior del Riu de les Coces (Alt Maestral, Castellón). Partiendo de los problemas derivados de la naturaleza de la información manejada se aborda su contextualización en el marco de la secuencia arqueológica y del hábitat del Holoceno inicial en el Maestrazgo y en el contexto regional. Los resultados obtenidos permiten por un lado, relativizar la idea de una secuencia local continua e ininterrumpida desde el Magdaleniense superior hasta el Mesolítico Reciente, y por otro. la sucesión de dos modelos diferentes de ocupación del territorio.
"Wymuszona mobilność - wymuszona osiadłość". O powojennych przesiedleniach i ich obecnych skutkach dla lokalnych społeczności
2016
We współczesnym dyskursie publicznym dotyczącym II wojny światowej rzadko wspomina się o masowych powojennych ruchach ludności w Europie, o przesiedleniach Polaków z Kresów Wschodnich II Rzeczypospolitej, wysiedleniach Niemców i przesiedleniach ludności ukraińskiej. Procesy „wymuszonej mobilności, jak i wymuszonej osiadłości”, stanowiące codzienność tamtych lat zaowocowały upadkiem wielu lokalnych mikroświatów, powstaniem nowych ojczyzn, nowych społeczności i nowych tożsamości. Konfrontacja odmiennych kulturowo światów „gospodarzy” i „gości”, międzygrupowe konflikty, aspiracje do „lepszego życia”, stały się między innymi źródłem „nowych mobilności”, które nadal trwają. Artykuł będzie zatem …