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showing 10 items of 4470 documents

Immunization Status against Measles of Health-Care Workers Operating at Three Sicilian University Hospitals: An Observational Study

2019

Measles is a highly contagious vaccine-preventable disease (VPD) that also commonly affects health-care workers (HCWs). Measles immunization of HCWs was strongly recommended by international health authorities, in order to limit the spreading of the illness to susceptible patients and colleagues. An observational study, evaluating the immunization and vaccination status against measles of HCWs working at three Sicilian university hospitals, was conducted. All subjects not completely immune (vaccinated with only one dose in their lifetime), not immune (not vaccinated or not naturally immunized), and with an unknown immunization status were considered not immunized. Among HCWs operating in th…

0301 basic medicinehealth care facilities manpower and servicesanimal diseases030106 microbiologyImmunologyeducationlcsh:Medicinechemical and pharmacologic phenomenaDiseaseSettore MED/42 - Igiene Generale E ApplicataMeaslesArticle03 medical and health sciences0302 clinical medicineEnvironmental healthDrug DiscoveryHealth careHealth-care personnel Vaccine hesitancy Vaccine-preventable diseasemedicinePharmacology (medical)vaccine-preventable disease030212 general & internal medicinePharmacologybusiness.industrylcsh:RInternational healthhealth-care personnelbiochemical phenomena metabolism and nutritionmedicine.diseaseUniversity hospitalVaccinationInfectious DiseasesImmunizationHealth-care personnel; Vaccine hesitancy; Vaccine-preventable diseasebacteriavaccine hesitancyObservational studybusinessVaccines
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Real life experiences in HCV management in 2018

2019

Introduction: Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Treatment of chronic hepatitis C has considerably improved in the last few years thanks to the introduction of direct-acting antivirals able to achieve sustained virological response in more than 95% of patients. Successful anti-HCV treatment can halt liver disease progression and solve the HCV-related extra-hepatic manifestations, eventually reducing liver-related and overall mortality. Areas covered: With the aim to respond to unmet needs in patient’s identification, universal access to antiviral therapy and treatment optimiza…

0301 basic medicinehepatitis C virusSofosbuvirSustained Virologic ResponseAntiviral therapyAntiviral therapy; chronic liver disease; DAAs; HCV; hepatitis C virus; Microbiology; Microbiology (medical); Infectious Diseases; Virologymedicine.disease_causeChronic liver diseaseHealth Services Accessibility0302 clinical medicinedirect acting antiviralshepatitis C viruMass Screening030212 general & internal medicineChronicComputingMilieux_MISCELLANEOUSHepatitis CHepatitis BHepatitis CPibrentasvirAntiviral therapy; chronic liver disease; DAAs; HCV; hepatitis C virus; Antiviral Agents; Disease Progression; Health Services Accessibility; Hepatitis C Chronic; Humans; Italy; Mass Screening; Sustained Virologic ResponseInfectious DiseasesItalyHCVDisease ProgressionAntiviral therapy; chronic liver disease; DAAs; HCV; hepatitis C virus; Antiviral Agents; Disease Progression; Health Services Accessibility; Hepatitis C; Chronic; Humans; Italy; Mass Screening; Sustained Virologic Responsemedicine.drugHumanMicrobiology (medical)Settore MED/17 - Malattie InfettiveHepatitis C virus030106 microbiologyInfectious DiseaseAntiviral AgentsMicrobiology03 medical and health sciencesVirologymedicineHumansAntiviral therapy; DAAs; HCV; chronic liver disease; direct acting antivirals; hepatitis C virusMass screeningDAAHepatitis B virusAntiviral Agentbusiness.industrychronic liver diseaseDAAsHepatitis C Chronicmedicine.diseaseVirologybusiness
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An "aubergine" in the heart: huge native mitral valve endocarditis caused by Streptococcus agalactiae.

2017

0301 basic medicinemedicine.medical_specialtyFever030106 microbiologyMEDLINE030204 cardiovascular system & hematologymedicine.disease_causeStreptococcus agalactiae03 medical and health sciencesMitral valve endocarditis0302 clinical medicineStreptococcal InfectionsInternal MedicinemedicineHumansIntensive care medicineEndocarditisbusiness.industryMiddle AgedDyspneaStreptococcus agalactiaeItalyEchocardiographyEmergency MedicineChordae TendineaeMitral ValveFemalebusinessEmergency Service HospitalInternal and emergency medicine
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Proceedings of the 3rd BEAT-PCD Conference and 4th PCD Training School

2018

Abstract Primary ciliary dyskinesia (PCD) is a chronic suppurative airways disease that is usually recessively inherited and has marked clinical phenotypic heterogeneity. Classic symptoms include neonatal respiratory distress, chronic rhinitis since early childhood, chronic otitis media, recurrent airway infections leading to bronchiectasis, chronic sinusitis, laterality defects with and without congenital heart disease including abnormal situs in approximately 50% of the cases, and male infertility. Lung function deteriorates progressively from childhood throughout life. ‘Better Experimental Approaches to Treat Primary Ciliary Dyskinesia’ (BEAT-PCD) is a network of scientists and clinician…

0301 basic medicinemedicine.medical_specialtyHeart diseaseeducationlcsh:Medicine610 Medicine & healthMeeting ReportGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicinePrimary ciliary dyskinesia360 Social problems & social servicesEpidemiologymedicineotorhinolaryngologic diseasesEarly childhood610 Medicine & healthlcsh:SciencePrimary ciliary dyskinesiaBronchiectasisMultidisciplinarybusiness.industrylcsh:RChronic sinusitisGeneral Medicinemedicine.diseaseChronic respiratory diseaseClinical trial030104 developmental biology030228 respiratory systemFamily medicinelcsh:QbusinessWorking group360 Social problems & social servicesBMC Proceedings
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Vaccination in multiple sclerosis patients treated with highly effective disease-modifying drugs: an overview with consideration of cladribine tablets

2021

Infectious diseases are an important consideration in autoimmune conditions such as multiple sclerosis. Infective episodes may trigger relapses and significantly deteriorate the course of the disease. Some immunotherapies may cause increased rates of infection-related adverse events. Thus, infection and vaccine-related issues should be included in the individualized patient-specific treatment strategy and counseling before starting therapy and regularly on treatment. Clinical and epidemiological studies as well as pharmacovigilance data repeatedly demonstrated the safety of the great majority of vaccines in multiple sclerosis patients. Moreover, studies have shown that vaccinations with kil…

0301 basic medicinemedicine.medical_specialtyMedizincladribine tabletsDiseaseReviewimmunizationmultiple sclerosis1117 Public Health and Health Services03 medical and health sciences0302 clinical medicineNatalizumabInternal medicinevaccinePharmacovigilancemedicineddc:610CladribineAdverse effectRC346-42911 Medical and Health SciencesPharmacologybusiness.industryMultiple sclerosisCOVID-19Vaccine efficacymedicine.diseaseVaccinationCoronavirus030104 developmental biologyNeurology1107 ImmunologyNeurology (clinical)Neurology. Diseases of the nervous systembusiness030217 neurology & neurosurgerymedicine.drugTherapeutic Advances in Neurological Disorders
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Behavioral and clinical characteristics of people receiving medical care for HIV infection in an outpatient facility in Sicily, Italy

2016

Paola Di Carlo,1 Giuliana Guadagnino,1 Palmira Immordino,1 Giovanni Mazzola,2 Pietro Colletti,2 Ilenia Alongi,1 Lucia Adamoli,1 Francesco Vitale,1 Alessandra Casuccio1 1Department of Sciences for Health Promotion and Mother-Child Care “G D’Alessandro”, University of Palermo, 2Department of Medicinal Clinics and Emerging Diseases, “Paolo Giaccone” Polyclinic University Hospital, Palermo, Italy Aim: The authors examined a cohort of HIV-positive outpatients at the AIDS Center of Palermo University in Italy in order to identify factors related to the frequency of their visits to the outpatient facility for health care services.Methods: Two hundr…

0301 basic medicinemedicine.medical_specialtyMultivariate analysisSettore MED/17 - Malattie Infettivehard-to-reach groups030106 microbiologyHuman immunodeficiency virus (HIV)Medicine (miscellaneous)HIV Outpatient Servicemedicine.disease_causeSettore MED/42 - Igiene Generale E Applicata03 medical and health sciences0302 clinical medicineOutpatient facilityAmbulatory careAcquired immunodeficiency syndrome (AIDS)CD4+ T-cell countHealth careMedicine030212 general & internal medicinePharmacology Toxicology and Pharmaceutics (miscellaneous)Access to care; CD4+ T-cell count; Hard-to-reach groups; HIV infection; HIV outpatient service; Resource use; Social Sciences (miscellaneous); Medicine (miscellaneous); Health Policy; Pharmacology Toxicology and Pharmaceutics (miscellaneous)Original Researchaccess to carelcsh:R5-920business.industryHealth PolicyUnivariatemedicine.diseaseHIV infectionresource usePatient Preference and AdherenceEmergency medicineCohortbusinesslcsh:Medicine (General)Hard-to-reach groupSocial Sciences (miscellaneous)
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Pathways of care for HIV infected children in Beira, Mozambique: pre-post intervention study to assess impact of task shifting

2018

Abstract Background In 2013, Mozambique implemented task-shifting (TS) from clinical officers to maternal and child nurses to improve care for HIV positive children < 5 years old. A retrospective, pre-post intervention study was designed to evaluate effectiveness of a new pathway of care in a sample of Beira District Local Health Facilities (LHFs), the primary, local, community healthcare services. Methods The study was conducted by accessing registries of At Risk Children Clinics (ARCCs) and HIV Health Services. Two time periods, pre- and post-intervention, were compared using a set of endpoints. Variables distribution was explored using descriptive statistics. T-student, Mann Whitney and …

0301 basic medicinemedicine.medical_specialtyReferralHIV InfectionsHIV infected childrenSettore MED/42 - Igiene Generale E ApplicataPost-intervention03 medical and health sciences0302 clinical medicineHIV exposed infants; HIV infected children; Human immunodeficiency virus; Paediatric HIV care and treatment; Pathways of care; Task-shiftingIntervention (counseling)EpidemiologyHealth caremedicineHumansHealth Workforce030212 general & internal medicineHuman immunodeficiency viruReferral and ConsultationMozambiqueRetrospective StudiesDescriptive statisticsbusiness.industryHuman immunodeficiency virusPublic healthlcsh:Public aspects of medicinePaediatric HIV care and treatmentPublic Health Environmental and Occupational HealthInfantHIV exposed infantlcsh:RA1-1270030112 virologyTask-shiftingHIV exposed infantsCD4 Lymphocyte CountChild PreschoolFamily medicineHealth Services ResearchBiostatisticsbusinessDelivery of Health CarePathways of careResearch ArticleBMC Public Health
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Impact of Communicative and Informative Strategies on Influenza Vaccination Adherence and Absenteeism from Work of Health Care Professionals Working …

2019

Every year, about 20% of health care workers (HCWs) acquire influenza, continuing to work and encouraging virus spreading. Influenza vaccination coverage rates and absenteeism from work among HCWs of the University Hospital (UH) of Palermo were analyzed before and after the implementation of several initiatives in order to increase HCWs&rsquo

0301 basic medicinemedicine.medical_specialtyinformative strategieshealth care facilities manpower and serviceseducation030106 microbiologyImmunologylcsh:MedicineArticlehealth care workers03 medical and health sciences0302 clinical medicineDrug DiscoveryHealth caremedicineHealth care workerPharmacology (medical)030212 general & internal medicineWeb sitePharmacologyvaccination coveragebusiness.industrylcsh:Rvirus diseasesMean ageCommunication campaignUniversity hospitalinfluenza vaccinationVaccinationInfectious DiseasesWork (electrical)Vaccination coverageFamily medicineInformative strategieAbsenteeismcommunication campaignsbusinessVaccines
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Application of a portable instrument for rapid and reliable detection of SARS-CoV-2 infection in any environment

2020

Abstract The ongoing outbreak of the novel coronavirus (SARS‐CoV‐2) infection is creating serious challenges for health laboratories that seek to identify viral infections as early as possible, optimally at the earliest appearance of symptom. Indeed, there is urgent need to develop and deploy robust diagnostic methodologies not only to use in health laboratory environments but also directly in places where humans circulate and spread the virus such as airports, trains, boats, and any public aggregation places. The success of a reliable and sensitive asymptomatic diagnosis relies on the identification and measurement of informative biomarkers from human host and virus in a rapid, sensitive, …

0301 basic medicineportableSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralImmunologycoronavirusBiologymedicine.disease_causeSensitivity and SpecificityDisease OutbreaksWorkflowBetacoronavirus03 medical and health sciencesCOVID-19 Testing0302 clinical medicinePandemicmedicineAnimalsHumansMass ScreeninginstrumentImmunology and AllergyBiomarker discoveryAsymptomatic InfectionsPandemicsdeviceMass screeningCoronavirusInvited ReviewClinical Laboratory TechniquesSARS-CoV-2COVID-19Reproducibility of ResultsClinical Laboratory Servicescoronavirus; device; instrument; portable; SARS-CoV-2 detection; Animals; Asymptomatic Infections; Betacoronavirus; Biomarkers; Clinical Laboratory Services; Clinical Laboratory Techniques; Coronavirus Infections; Disease Outbreaks; Humans; Mass Screening; Pandemics; Pneumonia Viral; Reproducibility of Results; Sensitivity and Specificity; WorkflowIdentification (information)030104 developmental biologyWorkflowRisk analysis (engineering)SARS‐CoV‐2 detectionCoronavirus InfectionsHost (network)Biomarkers030215 immunology
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Functional test measures as risk indicators for low back pain among fixed-wing military pilots.

2015

Purpose The purpose of this study was to find out the risk value of functional fitness test (FFT) results for low back pain (LBP) among fixed-wing military pilots. Methods A total of 104 male military pilots were recruited for this study. The study was conducted with a self-administered questionnaire and FFT. The functional tests were performed in the beginning of study (baseline). The questionnaire was carried out at the baseline and 5 years later. Results The isometric low back endurance test result was associated with physical activity-related LBP experienced 5 years later. Demographic information was not associated with LBP. The prevalence of overall LBP was 71% and the flight-related L…

030110 physiology0301 basic medicineAdultMalemedicine.medical_specialtyFunctional trainingIsometric exerciseCohort Studies03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationFixed wingRisk Factorshealth services administrationSurveys and QuestionnairesPrevalenceMedicineHealth Status IndicatorsHumans030212 general & internal medicineMuscle StrengthRange of Motion Articularbusiness.industrypathological conditions signs and symptomsGeneral MedicineLow back painnervous system diseasesTest (assessment)body regionsOccupational DiseasesMilitary personnelPilotsMilitary PersonnelPhysical therapyExercise Testpopulation characteristicsAviation medicinemedicine.symptombusinessLow Back PainCohort studyJournal of the Royal Army Medical Corps
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