Search results for "setting"

showing 10 items of 294 documents

Injectable Versus Oral First-Line Disease-Modifying Therapies: Results from the Italian MS Register

2021

AbstractThe current study aims to compare injectable and oral first-line disease-modifying therapies (DMTs) for time to first relapse, time to confirmed disability progression (CDP), and time to discontinuation using a cohort of relapsing remitting multiple sclerosis (RRMS) patients, with data extracted from the Italian MS Register. This multicenter, observational, retrospectively acquired, and propensity-adjusted cohort study utilized RRMS-naïve patients from the Italian MS Register who started either injectable or oral first-line DMTs between January 1, 2010, and December 31, 2017, to evaluate the impact on disability outcomes in patients. Enrolled patients were divided into two groups, n…

Maleoral DMTsoral DMTAdministration OralDiseaseRelapsing-RemittingCohort Studies0302 clinical medicineImmunologicinjectable DMTPharmacology (medical)030212 general & internal medicineRegistriesSubcutaneousMiddle AgedItalyEDSS score; injectable DMTs; Multiple sclerosis; oral DMTs; real-world setting; Adjuvants Immunologic; Administration Oral; Adult; Cohort Studies; Female; Follow-Up Studies; Glatiramer Acetate; Humans; Immunologic Factors; Injections Subcutaneous; Interferon-beta; Italy; Male; Middle Aged; Multiple Sclerosis Relapsing-Remitting; Retrospective Studies; RegistriesAdministrationCohortSettore MED/26 - NeurologiaOriginal ArticleFemaleNeurosurgeryCohort studyOralAdultmedicine.medical_specialtyEDSS scoreInjections SubcutaneousLower riskInjectionsMultiple sclerosis03 medical and health sciencesMultiple Sclerosis Relapsing-RemittingAdjuvants ImmunologicInternal medicinereal-world settingmedicineHumansImmunologic FactorsMultiple sclerosiAdjuvantsinjectable DMTsRetrospective StudiesPharmacologybusiness.industryMultiple sclerosisGlatiramer AcetateInterferon-betamedicine.diseaseDiscontinuationObservational studyNeurology (clinical)business030217 neurology & neurosurgeryFollow-Up Studies
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Entrepreneurial competencies and motivations to enhance marketing innovation in Europe

2017

Global Entrepreneurship Monitor (GEM) country profile variables were analyzed using qualitative comparative analysis (QCA). This analysis identified which combinations of entrepreneurs’ competencies and motivations boost marketing innovation. Marketing innovation contributes to defining and reinforcing competitive advantages, goal setting, and business performance. The findings of this study can help policymakers design strategies to foster regional marketing innovation and economic growth.

MarketingEntrepreneurshipMarketing innovationKnowledge managementbusiness.industryQualitative comparative analysis05 social sciencesCompetitive advantageMarketing strategyMarketing management0502 economics and business050207 economicsMarketingMarketing researchbusinessGoal setting050203 business & managementApplied PsychologyPsychology & Marketing
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Can goal setting and performance feedback enhance organizational citizenship behavior?

2008

MarketingOrganizational citizenship behaviorPerformance feedbackOrganizational behavior managementGoal orientationStrategy and Managementmedia_common.quotation_subjectOrganizational commitmentAltruismBusinessBusiness and International ManagementSocial psychologyGoal settingmedia_common
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Political Skills in Organizations: Do Personality and Reputation Play a Role?

2008

between altruistic behavior (goodwill toward co workers) and compliance behavior (attitude to ward the firm and its regulations, mission, etc.). It turned out that job satisfaction was related to formal performance and compliance behavior, but not to altruistic behavior. Job commitment was also related to formal performance. Finally, goal setting was related to formal performance and altruistic behavior but was not connected to com pliance behavior. In the second stage of the study, supervisors who had participated in earlier evaluations reas sessed employees' performance and feedback. The feedback included information about formal goal attainment as well as informal behaviors such as suppo…

MarketingOrganizational citizenship behaviorbusiness.industryStrategy and Managementmedia_common.quotation_subjectManagement stylesPublic relationsOrganizational behaviorJob performanceJob satisfactionBusiness and International ManagementbusinessPsychologyGoal settingSocial psychologyReputationmedia_commonSocial behaviorAcademy of Management Perspectives
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Curing of an epoxy resin modified with nanoclay monitored by dielectric spectroscopy and rheological measurements

2006

Dielectric and rheological measurements have been performed in “real-time” to follow curing reaction on blends of a diglycidyl ether of bisphenol-A epoxy resin with 4,4-methylene bis(2,6-diethylaniline) hardener and different amounts of organically modified nanoclay (Nanofil 919) as modifier. The effect of the modifier and its amount on the curing reaction, as well as that of the curing temperature has been studied. Changes in molecular mobility in the reaction mixture have been investigated by dielectric relaxation spectroscopy. Evolutions of ionic conductivity and main relaxation have been analyzed and vitrification times have been obtained and compared with those obtained by rheological …

Materials scienceDiglycidyl etherNanocompositePolymers and PlasticsThermosetting polymerGeneral ChemistryEpoxyDielectricSurfaces Coatings and FilmsDielectric spectroscopychemistry.chemical_compoundchemistryvisual_artMaterials Chemistryvisual_art.visual_art_mediumOrganoclayComposite materialCuring (chemistry)Journal of Applied Polymer Science
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The effect of a liquid CTBN rubber modifier on the thermo-kinetic parameters of an epoxy resin during a pultrusion process

2003

Abstract Rheo-kinetic behaviour of an epoxy resin, coupled with an anhydride hardener, with different CTBN liquid rubber concentration (0–15 phr), used in fibre reinforced plastics, was analysed comparing experimental data with theoretical models. The modelling of technological pultrusion process for thermoset matrix composites, developed through a numerical code realised with MATLAB, is reported, too. The model includes conduction and cure heat, degree of cure and viscosity evolution during the curing within the die. Considerable differences in process condition, using different rubber amount, are obtained. The numerical modelling of process conditions shows that the CTBN rubber presence i…

Materials scienceGeneral EngineeringConcentration effectThermosetting polymerCuring Computational simulationpultrusionEpoxyThermal conductionSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiNatural rubberPultrusionvisual_artHeat transferCeramics and Compositesvisual_art.visual_art_mediumComposite materialCuring (chemistry)
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Fracture Toughness of Hydrothermally Aged Epoxy Systems with Different Crosslink Density

2015

Abstract The present work investigates the fracture toughness behaviour of Single Edge Notched Bending (SENB) samples of epoxy systems subject to water uptake aging. Two epoxy systems with a significantly different Glass Transition Temperature, T g , are in particular considered: a typical commercial non-aeronautical grade resin matrix for composite applications, reaching a T g of 90 °C, and a DGEBA+DDS epoxy system achieving a T g of 230 °C.The materials have been conditioned by hydrothermal aging in a thermal bath at the temperature of 50 °C. TransmissionPhotoelastic Stress Analysisis carried outon SENB samples during water aging, monitoring the presence and evolution of swelling stresses…

Materials sciencePhotoelastic Stress AnalysiImage AnalysiComposite numberPhotoelastic Stress AnalysisStress (mechanics)Thermosetting ResinFracture toughnessEngineering (all)Fracture ToughnessHydrothermal AgingFracture Toughness; Hydrothermal Aging; Image Analysis; Photoelastic Stress Analysis; Swelling Stresses; Thermosetting Resin; Engineering (all)Composite materialEngineering(all)Image Analysis.General MedicineEpoxyDynamic mechanical analysisFracture ToughneSwelling StresseSwelling Stressesvisual_artvisual_art.visual_art_mediumFracture (geology)Gravimetric analysisGlass transition
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Thermomechanical properties of radiation-modified blends of polyethylene with liquid crystalline copolyester

1999

The results of investigation of gamma irradiated blends of high-density polyethylene (PE) with thermotropic polymer liquid crystal (PLC) are presented. The PLC used was a copolyester of 40% poly(ethylene terephthalate) with 60% p-(hydroxy-benzoic acid). The PLC content in the blends was 0, 5, and 10 wt%. The constituents were blended with the use of a single screw extruder. The specimens were prepared by compression molding. The irradiation of the samples was performed by a Co 60 γ-radiation source in inert atmosphere (argon) up to absorbed relatively low doses (up to 200 kGy: 1 Mrad = 10 kGy). The morphological, thermal, and mechanical properties were investigated for irradiated and unirra…

Materials sciencePolymers and PlasticsThermosetting polymerCompression moldingGeneral ChemistryPolyethyleneThermotropic crystalCopolyesterchemistry.chemical_compoundchemistryMaterials ChemistryMelting pointIrradiationPolymer blendComposite materialPolymer Engineering & Science
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Study and comparison of interaction parameters and phase behavior of epoxy/polystyrene and epoxies copolymer polystyrene-b-poly(methyl methacrylate) …

2008

Thermodynamic studies in terms of phase separation behavior and interaction parameters, in mixtures of epoxy resins (thermoset materials) with thermoplastic additives, consisting of polystyrene (PS) or polystyrene-b-poly(methyl methacrylate) P(S-MMA) (with small proportion of MMA), have been carried out. It can be confirmed that the solubility of P(S-MMA) is an improvement on that of PS, with the prepolymer epoxy resins. Moreover, the interaction parameters are positive at temperatures in which phase separation is observed, but negative at temperatures in which the phase separation window disappears, in the corresponding phase diagram. POLYM. COMPOS., 2008. © 2008 Society of Plastics Engine…

Materials sciencePolymers and PlasticsThermosetting polymerGeneral ChemistryEpoxyPoly(methyl methacrylate)chemistry.chemical_compoundchemistryPhase (matter)visual_artMaterials ChemistryCeramics and Compositesvisual_art.visual_art_mediumPolystyrenePolymer blendMethyl methacrylateComposite materialPrepolymerPolymer Composites
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Thermosetting composites based on bronze particles for archaeological and artistic metal heritage cloning

2018

peer-reviewed Artificial Metals are polymeric semi-metallic composites obtained by combining thermosetting resins with atomized metal powders in order to achieve composite materials capable of reproducing metals, even in a rusty or corroded condition. These composites provide a solution for the reproduction of archaeological artefacts, sculptures, and ornaments for the purpose of conservation. This work explores mechanical properties of three different resins bronze composites loaded with two different proportions of metal filler. The degree of conversion of the samples was measured by differential scanning calorimetry (DSC) and flexural tests were carried out to determine their mechanical …

Materials scienceScanning electron microscopeThermosetting polymer02 engineering and technologyengineering.material01 natural sciencesArticleMetalDifferential scanning calorimetryFlexural strengthFiller (materials)lcsh:Social sciences (General)BronzeComposite materiallcsh:Science (General)Microscale chemistryMultidisciplinary010401 analytical chemistry021001 nanoscience & nanotechnologyArchaeologyMaterials science0104 chemical sciencesArchaeologyPINTURAvisual_artengineeringvisual_art.visual_art_mediumlcsh:H1-990210 nano-technologylcsh:Q1-390Heliyon
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