Search results for "sig"
showing 10 items of 19670 documents
Don't tell us: the demand for secretive bahaviour
2009
International audience
Minimizing fleet operating costs for a container transportation company
2006
Abstract This paper focuses on a fleet management problem that arises in container trucking industry. From the container transportation company perspective, the present and future operating costs to minimize can be divided in three components: the routing costs, the resource (i.e., driver and truck) assignment costs and the container repositioning costs (i.e., the costs of restoring a given container fleet distribution over the serviced territory, as requested by the shippers that own the containers). This real-world problem has been modeled as an integer programming problem. The proposed solution approach is based on the decomposition of this problem in three simpler sub-problems associate…
Search for photonic signatures of gauge-mediated supersymmetry in 8TeV pp collisions with the ATLAS detector
2015
A search is presented for photonic signatures motivated by generalized models of gauge-mediated supersymmetry breaking. This search makes use of 20.3 fb[superscript −1] of proton-proton collision data at √s = 8 TeV recorded by the ATLAS detector at the LHC, and explores models dominated by both strong and electroweak production of supersymmetric partner states. Four experimental signatures incorporating an isolated photon and significant missing transverse momentum are explored. These signatures include events with an additional photon, lepton, b-quark jet, or jet activity not associated with any specific underlying quark flavor. No significant excess of events is observed above the Stand…
Recommendations of the LHC Dark Matter Working Group: Comparing LHC searches for dark matter mediators in visible and invisible decay channels and ca…
2019
Physics of the Dark Universe 26, 100377 (2019). doi:10.1016/j.dark.2019.100377
Efectos del fútbol como ocupación deportiva en el proceso de recuperación de personas con trastorno mental grave: impacto sobre el insight cognitivo,…
2023
Introducción: Las personas con trastorno mental grave presentan una necesidad de ayuda que conlleva múltiples acciones rehabilitadoras. Estas, se llevan a cabo actualmente desde el modelo de recuperación o recovery, en el que el foco de la recuperación es la valoración de las propias personas afectadas y se propone la necesidad de la ocupación humana como un tipo de intervención rehabilitadora basada en proporcionar espacios ocupacionales para la exploración, la competencia y el logro. La literatura pone de manifiesto que la práctica del ejercicio físico y, específicamente, de una actividad deportiva, como espacio ocupacional, constituye un medio que en numerosas ocasiones se propone como u…
A Band Model of Cambium Development: Opportunities and Prospects
2021
More than 60% of tree phytomass is concentrated in stem wood, which is the result of periodic activity of the cambium. Nevertheless, there are few attempts to quantitatively describe cambium dynamics. In this study, we develop a state-of-the-art band model of cambium development, based on the kinetic heterogeneity of the cambial zone and the connectivity of the cell structure. The model describes seasonal cambium development based on an exponential function under climate forcing which can be effectively used to estimate the seasonal cell production for individual trees. It was shown that the model is able to simulate different cell production for fast-, middle- and slow-growing trees under …
Synthesis and biological evaluation of the antioxidant properties of new analogues of natural products with piperidine based structure and evaluation…
Una nueva aproximación al estudio de la delincuencia en el Reino de Valencia (1580-1609)
2021
En la investigación se aborda el mundo de la delincuencia en el Antiguo Reino de Valencia a fines del siglo XVI y principios del XVII. Partiendo de una fuente principal, Maestre Racional, serie Tesorería General, que se custodia en el Archivo del Reino de Valencia y que recoge los delitos incoados por los altos tribunales de justicia del Reino, se pretende conocer a los delincuentes que cometían sus tropelías en este territorio, originarios del mismo o que llegaban a él procedentes de otros lugares y, por supuesto, quiénes fueron las víctimas de los actos violentos. Se han definido aspectos esenciales como el perfil socio-profesional, el estatus o los lugares de origen tanto de las víctimas…
Targeting the Activin Receptor Signaling to Counteract the Multi-Systemic Complications of Cancer and Its Treatments
2021
Muscle wasting, i.e., cachexia, frequently occurs in cancer and associates with poor prognosis and increased morbidity and mortality. Anticancer treatments have also been shown to contribute to sustainment or exacerbation of cachexia, thus affecting quality of life and overall survival in cancer patients. Pre-clinical studies have shown that blocking activin receptor type 2 (ACVR2) or its ligands and their downstream signaling can preserve muscle mass in rodents bearing experimental cancers, as well as in chemotherapy-treated animals. In tumor-bearing mice, the prevention of skeletal and respiratory muscle wasting was also associated with improved survival. However, the definitive proof tha…
Leisure-time physical activity and DNA methylation age : a twin study
2019
Background: Epigenetic clocks may increase our understanding on human aging and how genetic and environmental factors regulate an individual aging process. One of the most promising clocks is Horvath’s DNA methylation (DNAm) age. Age acceleration, i.e., discrepancy between DNAm age and chronological age, tells us whether the person is biologically young or old compared to his/her chronological age. Several environmental and lifestyle factors have been shown to affect life span. We investigated genetic and environmental predictors of DNAm age in young and older monozygotic (MZ) and dizygotic (DZ) twins with a focus on leisure time physical activity. Results: Quantitative genetic modeling rev…