Search results for "significance"

showing 10 items of 532 documents

Treatment of idiopathic oligozoospermia with tamoxifen--a randomized controlled study.

1992

There is no conclusive evidence of the usefulness of tamoxifen in the treatment of idiopathic oligozoospermia (OAT-syndrome), as it has been used mostly in uncontrolled studies. We herein report on the controlled treatment of OAT-syndrome with tamoxifen versus placebo following a randomized design. Seventy-six men with sperm counts of 2-20 x 10(6) ml-1, sperm motility of 20-50%, and sperm morphology (abnormal cells) between 50 and 80% were involved in the study. Patients with varicocele, a history of testicular maldescent or genital inflammation were excluded. Thirty-nine patients received tamoxifen (30 mg daily), 37 patients placebo. There was a statistically significant increase in the me…

AdultMalemedicine.medical_specialtyUrologyEndocrinology Diabetes and MetabolismVaricoceleUrologyPlacebolaw.inventionRandomized controlled triallawStatistical significanceInternal medicinemedicineHumansTestosteroneSperm motilitySperm Countbusiness.industryOligospermiaLuteinizing HormoneAntiestrogenmedicine.diseaseSpermTamoxifenEndocrinologyReproductive MedicineSperm MotilityFollicle Stimulating HormonebusinessTamoxifenmedicine.drugInternational journal of andrology
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Erythrocyte deformability in morbid obesity before bariatric surgery. Influence of abdominal obesity.

2010

Although there are several studies dealing with erythrocyte deformability (ED) in obese patients, research on this topic in morbidly obese subjects is scarce. In these studies ED seems to be decreased, although the cause remains unknown. A case-control study in 76 morbid obese subjects (23 women and 53 men, aged 44 ± 13 years) and in 79 normal-weight controls (30 women and 49 men, aged 43 ± 13 years) was undertaken. ED has been determined by ektacytometric techniques in a Rheodyn SSD, by means of the elongation index (EI) at 12, 30 and 60 Pascals, along with anthropometric, lipidic, metabolic and inflammatory parameters. EI was statistically lower in morbidly obese subjects than in controls…

AdultMalemedicine.medical_specialtyWaistPhysiologyBariatric SurgeryInsulin resistancePhysiology (medical)Internal medicineStatistical significanceErythrocyte DeformabilitymedicineErythrocyte deformabilityHumansAbdominal obesitybusiness.industryHematologyAnthropometryMiddle Agedmedicine.diseaseObesitySurgeryObesity MorbidEndocrinologyCase-Control StudiesObesity AbdominalFemalemedicine.symptomInsulin ResistanceWaist CircumferenceCardiology and Cardiovascular MedicinebusinessBody mass indexClinical hemorheology and microcirculation
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Effects of different accentuated eccentric loads on acute neuromuscular, growth hormone, and blood lactate responses during a hypertrophic protocol.

2009

This study monitored acute neuromuscular responses and growth hormone (GH) and blood lactate (La) concentrations in the eccentric-concentric (ECC-CON) hypertrophic protocol by using various dynamic accentuated external resistance (DAER) loads in the bench press exercise. Male subjects (age = 32 +/- 4 years; n = 11) performed 4 sets of 10 repetitions with 2 minutes of recovery between the sets. The loads were 70, 80, 90, and 100% of 1 repetition maximum (RM) for the ECC phase, whereas 70% RM was constantly used for the CON phase. Electromyographic activity (EMG), ECC, CON, and isometric (ISOM) forces, serum GH and blood La, were measured at pre- and postloading. Significant reductions occurr…

AdultMalemedicine.medical_specialtygenetic structuresDeltoid curvePhysical Therapy Sports Therapy and RehabilitationIsometric exerciseElectromyographyBench pressMuscle hypertrophyInternal medicineStatistical significanceIsometric ContractionmedicineEccentricHumansOrthopedics and Sports MedicineMuscle SkeletalAnalysis of Variancemedicine.diagnostic_testAnthropometrybusiness.industryElectromyographyResistance TrainingGeneral MedicineEndocrinologyGrowth HormoneCardiologyLactatesAnalysis of variancebusinessJournal of strength and conditioning research
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Removal of annexin V–positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a contr…

2014

Objective To determine the effect of removing presumptive apoptotic sperm cells from samples from unselected males by means of magnetic activated cell sorting (MACS) on live-birth delivery rates after intracytoplasmic sperm injection (ICSI) in couples undergoing ovum donation (OD). Design Prospective, randomized, triple-blinded, and controlled study. Setting Private university-affiliated IVF center. Patient(s) A total of 237 infertile couples undergoing ICSI as part of an OD program. Intervention(s) Semen specimens from the control group were prepared by swim-up. Samples from the study group were prepared by swim-up followed by MACS and incubation with annexin V–conjugated microbeads to rem…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentApoptosisSemenCell SeparationFertilization in VitroPhosphatidylserinesBiologyIntracytoplasmic sperm injectionlaw.inventionAndrologyMagneticsHuman fertilizationRandomized controlled trialPregnancylawStatistical significancemedicineHumansSperm Injections IntracytoplasmicAnnexin A5Birth RateGynecologyPregnancyOocyte DonationObstetrics and Gynecologymedicine.diseaseSpermatozoaSpermConfidence intervalSperm MaturationReproductive MedicineFemaleFertility and Sterility
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Sexual Compulsivity and Sexual Sensation Seeking: A Preliminary Approach Among Male Sex Workers Compared to Gay Men in Spain

2015

This study aims to explore sexual compulsivity (SC) and sexual sensation seeking (SSS) in male sex workers (MSWs) compared to a group of non-MSW gay men. A total of 60 MSWs and 63 gay men answered the SC Scale and the SSS Scale. The total scales' mean score was slightly higher in the MSW population. Still, statistical differences were observed in only two SSS items. In spite of the absence of statistical significance, MSWs presented more sexual behavior interferences on their lives and higher failure to control sexual impulses. Future interventions among MSWs should focus on sexual self-control and impulsivity.

AdultMalesexual compulsivity050103 clinical psychologyPopulationSensationPsychological interventionSex workersImpulsivityRisk AssessmentDevelopmental psychologyYoung Adult03 medical and health sciencesSexual compulsivityRisk-Takingmale sex workersStatistical significancemedicineHumanssexual sensation seekingSensation seeking0501 psychology and cognitive sciencesHomosexuality Maleeducationgay meneducation.field_of_studySex Workers030505 public healthSocial Identification05 social sciencesClinical PsychologySexual behaviorSpainCompulsive Behaviormedicine.symptom0305 other medical sciencePsychologyClinical psychologyJournal of Sex & Marital Therapy
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Effect of continuous oestradiol-medroxyprogesterone administration on plasma lipids and lipoproteins

1991

Plasma lipids and lipoproteins were measured in 21 post-menopausal women after 4 and 8 months of continuous treatment with an orally administered combination of oestradiol and medroxyprogesterone acetate. The mean concentrations of cholesterol and low-density-lipoprotein (LDL) cholesterol were reduced by 12% (P less than 0.001) and 11% (P less than 0.01), respectively, after 4 months of treatment and by 9% (P less than 0.05) and 12% (P less than 0.05) after 8 months. The mean level of high-density-lipoprotein (HDL) cholesterol showed an initial fall of 5% (P less than 0.05) after 4 months and then increased by 13% (P less than 0.05) after 8 months of treatment. The plasma triglycerides leve…

AdultMedroxyprogesteronemedicine.medical_specialtymedicine.drug_classLipoproteinsMedroxyprogesteronemedicine.medical_treatmentGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundInternal medicinePlasma lipidsHumansMedicineMedroxyprogesterone acetateClinical significanceProspective StudiesEstradiolProgestogenbusiness.industryCholesterolEstrogen Replacement TherapyObstetrics and GynecologyMiddle AgedLipidsEndocrinologychemistryEstrogenDrug Therapy CombinationFemalelipids (amino acids peptides and proteins)Menopausebusinessmedicine.drugLipoproteinMaturitas
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Monocular versus binocular pupillometry.

2004

Purpose To quantify differences between monocular and binocular pupil size measurement under scotopic and mesopic conditions. Setting Department of Ophthalmology, Johannes Gutenberg-University, and Department of Medical Biometry, Epidemiology and Informatics, University of Mainz, Mainz, Germany. Methods Computerized dynamic pupillometry (P2000 SA, Procyon Instruments Ltd.) was used at 3 illumination levels: scotopic at 0.03 lux, mesopic low at 0.82 lux, and mesopic high at 6.4 lux. One hundred forty eyes of 70 healthy volunteers without ocular pathology were examined. The subjects were divided into 2 groups. In the first group, the pupil diameter was measured binocularly first. In the secon…

Adultgenetic structuresAdolescentMesopic visionmedicine.medical_treatmentDark AdaptationDiagnostic Techniques OphthalmologicalVision MonocularStatistical significanceRefractive surgeryMedicineHumansScotopic visionVision BinocularMonocularbusiness.industryPupileye diseasesSensory SystemsOphthalmologyQuartileOptometrySurgerysense organsbusinessBinocular visionPupillometryJournal of cataract and refractive surgery
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Oral and dental health status in patients with eating disorders in Madrid, Spain

2019

Background The aim of the present study was to describe and compare the oral and dental health status of two groups, one diagnosed with eating disorders (EDs), and another group without this pathology, assessing the following oral manifestations: dental alterations, periodontal disorders, soft tissue disorders, non-stimulated salivary flow, and oral pH. Material and Methods This comparative transversal epidemiological study included 179 participants, of whom 59 were diagnosed with EDs (Eating Disorder Group: EDG) and 120 had no antecedents of EDs (No Eating Disorder Group: NEDG). All patients fulfilled the following inclusion criteria: women aged over 18 years, diagnosed with an ED by a spe…

Adultmedicine.medical_specialtyAdolescentHealth StatusMEDLINEOral HealthClinical nutritionDental CariesOral hygieneFeeding and Eating Disorders03 medical and health sciences0302 clinical medicineStatistical significanceInternal medicineEpidemiologyHumansMedicineGeneral DentistrySocioeconomic statusOral Medicine and Pathologybusiness.industryResearchDental health030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseasestomatognathic diseasesEating disordersOtorhinolaryngologySpainUNESCO::CIENCIAS MÉDICASFemaleSurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Bed rest after embryo transfer negatively affects in vitro fertilization: a randomized controlled clinical trial.

2013

Objective To evaluate the influence of 10 minutes of bed rest after ET on the achievement of a live-born infant (LBI) in patients undergoing IVF treatment with oocyte donation (OD). Design Prospective, randomized, parallel assignment, controlled trial. Setting Private IVF center. Patient(s) A total of 240 patients undergoing a first IVF cycle with OD in our center. Intervention(s) Ten minutes of bed rest after ET or no bed rest, that is, allowing patients to ambulate immediately after the ET. Main Outcome Measure(s) The primary outcome was LBI rate per randomized patient. Secondary outcomes were implantation rate and biochemical and clinical miscarriage rates. Result(s) LBI rates (56.7% vs.…

Adultmedicine.medical_specialtyAdolescentPregnancy Ratemedicine.medical_treatmentFertilization in VitroBed restMiscarriagelaw.inventionYoung AdultRandomized controlled triallawPregnancyStatistical significancemedicineHumansEmbryo ImplantationPostoperative PeriodGynecologybusiness.industryInfant NewbornObstetrics and GynecologyMiddle Agedmedicine.diseaseEmbryo TransferEmbryo transferClinical trialPregnancy rateReproductive MedicineAnesthesiaInfertilityApgar scoreFemalebusinessAlgorithmsBed RestFertility and sterility
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Clinical significance of increased intraabdominal pressure in severe acute pancreatitis.

2002

The aim of the study was to assess whether increased intra-abdominal pressure affects the clinical course and reflects on the effectiveness of the conservative treatment in patients with severe acute pancreatitis. Data on 37 consecutive patients with severe acute pancreatitis that were collected prospectively included APACHE II score, daily measurement of the intra-abdominal pressure, and clinical routine. Group A consisted of 26 patients with intra-abdominal pressure < 25 cm/H 2 O during their treatment period, and group B consisted of 11 patients with intraabdominal pressure ≥ 25 cm/H 2 O. SIRS, MODS, complication rate and mortality were analysed. The age, APACHE II scores and hospital st…

Adultmedicine.medical_specialtyPancreatic diseaseMultiple Organ FailureSeverity of Illness IndexGroup BAbdomenOutcome Assessment Health CaremedicinePressureHumansClinical significanceProspective StudiesAgedAPACHE IIbusiness.industryGeneral MedicineLength of StayMiddle Agedmedicine.diseaseSurgerySurvival Ratemedicine.anatomical_structurePancreatitisAnesthesiaAcute DiseaseAbdomenPancreatitisAcute pancreatitisSurgerybusinessComplicationActa chirurgica Belgica
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