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showing 10 items of 2851 documents

TOWARDS AN ADVANCED CONSERVATION STRATEGY: A STRUCTURED DATABASE for SHARING 3D DOCUMENTATION between EXPERT USERS

2019

Abstract. Nowadays, the researchers in Cultural Heritage fields investigate more and more about advanced conservation strategies that comprehend the possibility to share and use 3D models and structured information related to them. One of the modern method adopted to achieve this goal is to use structured web-platform. These are online systems that can handle data, created to contain and support precise information. They simultaneously respond to the need for a common ground for different expert users and of a unique tool where to store several kinds of data, coming from heterogeneous sources. The article aims to show how it is possible to build a valid tool for the conservation and monitor…

lcsh:Applied optics. PhotonicsComputer science0211 other engineering and technologiesLegislation02 engineering and technologyConservationWeb Databasecomputer.software_genreCDE; Conservation; Digitalisation; Unesco Sites; Valorisation; Web Databaselcsh:TechnologyField (computer science)Documentation0601 history and archaeologyStructure (mathematical logic)060102 archaeologyDatabaselcsh:Tlcsh:TA1501-1820021107 urban & regional planning06 humanities and the artsCultural heritageDigitalisationlcsh:TA1-2040Unesco Siteslcsh:Engineering (General). Civil engineering (General)computerValorisationCDE
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The transcriptome analysis of Strongyloides stercoralis L3i larvae reveals targets for intervention in a neglected disease.

2012

Background: Strongyloidiasis is one of the most neglected diseases distributed worldwide with endemic areas in developed countries, where chronic infections are life threatening. Despite its impact, very little is known about the molecular biology of the parasite involved and its interplay with its hosts. Next generation sequencing technologies now provide unique opportunities to rapidly address these questions. Principal Findings: Here we present the first transcriptome of the third larval stage of S. stercoralis using 454 sequencing coupled with semi-automated bioinformatic analyses. 253,266 raw sequence reads were assembled into 11,250 contiguous sequences, most of which were novel. 8037…

lcsh:Arctic medicine. Tropical medicineSequence analysisHaemonchus-contortuslcsh:RC955-962Molecular Sequence DataComputational biologyBiologyBioinformaticsDNA sequencingStrongyloides stercoralisTranscriptomeParasitic DiseasesmedicineAnimalsHumansDictyocaulus-viviparusGene Expression Profilinglcsh:Public aspects of medicinePublic Health Environmental and Occupational HealthNeglected DiseasesFunctional genomicslcsh:RA1-1270Sequence Analysis DNADNA Protozoanmedicine.diseasebiology.organism_classificationGene expression profilingInfectious DiseasesStrongyloidiasisLarvaHost-Pathogen InteractionsStrongyloidesStrongyloidiasisMedicineHelminth-parasitesStrongyloides stercoralisFunctional genomicsResearch ArticleNeglected Tropical DiseasesPLoS Neglected Tropical Diseases
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Generation of Natural Runoff Monthly Series at Ungauged Sites Using a Regional Regressive Model

2016

Many hydrologic applications require reliable estimates of runoff in river basins to face the widespread lack of data, both in time and in space. A regional method for the reconstruction of monthly runoff series is here developed and applied to Sicily (Italy). A simple modeling structure is adopted, consisting of a regression-based rainfall–runoff model with four model parameters, calibrated through a two-step procedure. Monthly runoff estimates are based on precipitation, temperature, and exploiting the autocorrelation with runoff at the previous month. Model parameters are assessed by specific regional equations as a function of easily measurable physical and climate basin descriptors. Th…

lcsh:Hydraulic engineeringCalibration (statistics)ungauged sitesUngauged siteRainfall-runoff model0208 environmental biotechnologyGeography Planning and DevelopmentDrainage basinmonthly runoff series; Natural streamflow; Rainfall-runoff model; Regionalization; Regression method; Ungauged sites; Aquatic Science; Biochemistry; Water Science and Technology; Geography Planning and Development02 engineering and technologyAquatic ScienceStructural basinRunoff curve numberBiochemistrylcsh:Water supply for domestic and industrial purposeslcsh:TC1-978monthly runoff serieWater Science and TechnologyHydrologygeographylcsh:TD201-500geography.geographical_feature_categorynatural streamflowmonthly runoff series; regression method; rainfall–runoff model; regionalization; ungauged sites; natural streamflowAutocorrelationSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaRegression analysisrainfall–runoff model020801 environmental engineeringRunoff modelregression methodregionalizationEnvironmental scienceSurface runoffmonthly runoff seriesWater
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Prediction of Specific TCR-Peptide Binding From Large Dictionaries of TCR-Peptide Pairs

2019

Abstract The T cell repertoire is composed of T cell receptors (TCR) selected by their cognate MHC-peptides and naive TCR that do not bind known peptides. While the task of distinguishing a peptide-binding TCR from a naive TCR unlikely to bind any peptide can be performed using sequence motifs, distinguishing between TCRs binding different peptides requires more advanced methods. Such a prediction is the key for using TCR repertoires as disease-specific biomarkers. We here used large scale TCR-peptide dictionaries with state-of-the-art natural language processing (NLP) methods to produce ERGO (pEptide tcR matchinG predictiOn), a highly specific classifier to predict which TCR binds to which…

lcsh:Immunologic diseases. AllergyComputer scienceevaluation methodsT-LymphocytesT cellImmunologyReceptors Antigen T-CellEpitopes T-LymphocyteTarget peptidePeptide bindingPeptidechemical and pharmacologic phenomenaComputational biologyLigandsSoftware implementationautoencoder (AE)AntigenEvaluation methodsmedicineImmunology and AllergyHumansProtein Interaction Domains and MotifsEpitope specificityAntigensDatabases ProteinOriginal Researchchemistry.chemical_classificationBinding SitesT cell repertoireChemistryRepertoirelong short-term memory (LSTM)T-cell receptorepitope specificitydeep learninghemic and immune systemsmedicine.anatomical_structuremachine learningPeptidesSequence motiflcsh:RC581-607SoftwareProtein BindingSignal TransductionTCR repertoire analysisFrontiers in Immunology
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Phenotypic Buffering in a Monogenean: Canalization and Developmental Stability in Shape and Size of the Haptoral Anchors of Ligophorus cephali (Monog…

2015

Phenotypic variation results from the balance between sources of variation and counteracting regulatory mechanisms. Canalization and developmental stability are two such mechanisms, acting at two different levels of regulation. The issue of whether or not they act concurrently as a common developmental buffering capacity has been subject to debate. We used geometric morphometrics to quantify the mechanisms that guarantee phenotypic constancy in the haptoral anchors of Ligophorus cephali. Canalization and developmental stability were appraised by estimating inter- and intra-individual variation, respectively, in size and shape of dorsal and ventral anchors. The latter variation was estimated…

lcsh:MedicineStability (probability)Fluctuating asymmetryMorfologia (Biologia) -- MatemàticaParasites -- VariationAnimalsMorphology -- Mathematicslcsh:ScienceMorphometricsAnalysis of VariancePrincipal Component AnalysisMultidisciplinarybiologylcsh:RAnatomybiology.organism_classificationPhenotypeDactylogyridaeLigophorus cephaliFixation (population genetics)PhenotypePlatyhelminthsEvolutionary biologylcsh:QParàsits -- VariacióMonogeneaResearch ArticlePLoS ONE
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Corundum Anorthosites-Kyshtymites from the South Urals, Russia: A Combined Mineralogical, Geochemical, and U-Pb Zircon Geochronological Study

2019

Kyshtymites are the unique corundum-blue sapphire-bearing variety of anorthosites of debatable geological origin found in the Ilmenogorsky-Vishnevogorsky complex (IVC) in the South Urals, Russia. Their mineral association includes corundum-sapphire, plagioclase (An61&ndash

lcsh:QE351-399.2010504 meteorology & atmospheric sciencesGeochemistryMetamorphismengineering.material010502 geochemistry & geophysics01 natural sciencesIlmenogorsky-Vishnevogorsky complexAnorthositeUltramafic rockPlagioclasein situ LA-ICP-MS U-Pb zircon datingMetasomatismblue sapphire0105 earth and related environmental sciencessapphire geochemistrylcsh:MineralogyGeologyGeotechnical Engineering and Engineering GeologykyshtymitesanorthositesCarbonatiteengineeringProtolithGeologyZirconMinerals
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cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel

2020

Abstract Background Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understanding of how the effects of genetic variants affect different molecular mechanisms to determine gut immunocompetence is still limited. Results To address this, we perform a systems genetics analysis of the gut transcriptomes from 38 DGRP lines that were orally infected with Pseudomonas entomophila. We identify a large number of condition-specific, expression quantitative trait loci (local-eQTLs) with infection-specific ones located …

lcsh:QH426-470Quantitative Trait Locimotifsallele-specific expressionPolymorphism Single Nucleotidecomplex traitsgenerationPseudomonasAnimalsDrosophila ProteinsRegulatory Elements Transcriptionallcsh:QH301-705.5AllelesBinding SitesResearchF-Box ProteinsassociationForkhead Transcription FactorsGastrointestinal Tractlcsh:GeneticsDrosophila melanogasterlcsh:Biology (General)dissectionresponsesFemaleTranscriptomerevealsdiscoveryGenome Biology
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A Study of Mechanical Properties of Polymer Composite Membranes with Various Ionic Liquids at Elevated Temperatures

2019

This work was supported by Latvian Council of Science (Cooperation project No.666/2014.4).

lcsh:TN1-997KetoneMaterials science020209 energyProton exchange membrane fuel cellEther02 engineering and technologymechanical propertiesfuel cellchemistry.chemical_compound0203 mechanical engineering0202 electrical engineering electronic engineering information engineering:NATURAL SCIENCES:Physics [Research Subject Categories]General Materials Sciencelcsh:Mining engineering. Metallurgyionic liquidchemistry.chemical_classificationPolymer020303 mechanical engineering & transportsMembraneChemical engineeringchemistryIonic liquidPolymer compositesComposite membraneproton exchange membrane
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Green approach to corrosion inhibition of stainless steel in phosphoric acid of Artemesia herba albamedium using plant extract

2019

Essential oil from aerial parts of Artemisia herba-alba from Morocco was hydrodistilled and its chemical composition oil was investigated by capillary GC and GC/MS. The major components were 1,8-cineole (35.6%) and camphor (24.1%). Artemisia herba-alba essential oil AHAO was tested as corrosion inhibitor of stainless steel (SS) in 1M H3PO4 using potentiodynamic polarization (PDP) and electrochemical impedance spectroscopy measurements (EIS) and scanning electronically microscopy (SEM) studies. The results obtained showed that the essential oil of Artemisia reduces the corrosion rate. Tafel polarization method indicates that the plant extract behaves as a mixed type inhibitor. The inhibition…

lcsh:TN1-997Materials science02 engineering and technology01 natural sciencesEssential oilINGENIERIA QUIMICAAbsorciólaw.inventionCorrosionBiomaterialssymbols.namesakechemistry.chemical_compoundCorrosion inhibitorAdsorptionlaw0103 physical sciencesPhosphoric acidEssential oillcsh:Mining engineering. MetallurgyInhibition010302 applied physicsTafel equationArtemisia herba-albaMetals and AlloysLangmuir adsorption model021001 nanoscience & nanotechnologyStainless SteelSurfaces Coatings and FilmsDielectric spectroscopyCorrosionchemistryCeramics and CompositessymbolsAdsorptionAcer Corrosió0210 nano-technologyNuclear chemistry
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Development of Composites with a Self-Healing Function

2015

This research aimed to realize experimentally the facilevascular self-healing system in epoxy glass fibre reinforced composite. Using flexiblepolytetrafluoroethylene tubes as removable preforms, the channels were embeddedinto both neat epoxy resin and unidirectional glass-fibre reinforced epoxy laminate.Room temperature curable epoxy resin with a surfactant and an amine-basedhardener were the components of the binary healing agent. The specimens oftapered double cantilever beam geometry were subjected to Mode I fracture tests.Fracture of specimens released the healing agent from channels and triggeredself-healing process of the crack. Tested neat epoxy resin specimensdemonstrated recovery o…

lcsh:TN1-997Materials scienceCantileverepoxy matrixvascular approachComposite numberGlass fiberEpoxyBendingsmart compositesFracture toughnessFlexural strengthvisual_artvisual_art.visual_art_mediumself-healingGeneral Materials ScienceComposite materialElastic moduluslcsh:Mining engineering. MetallurgyMaterials Science
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