Search results for "skeletal muscle"

showing 10 items of 430 documents

Cellular-free magnesium depletion in brain and muscle of normal and preeclamptic pregnancy: A nuclear magnetic resonance spectroscopic study

2004

Preeclampsia is a pregnancy disorder of unknown origin, characterized by vasospasm, elevated blood pressure, and increased neuromuscular irritability, features common to syndromes of magnesium deficiency. Evidence of serum and ionized magnesium metabolism disturbances have been observed in women with preeclampsia. This and the therapeutic utility of magnesium in preeclampsia led us to investigate the extent to which an endogenous tissue magnesium deficiency might be present in and contribute to its pathophysiology. We used 31 P nuclear magnetic resonance spectroscopy to noninvasively measure in situ intracellular-free magnesium levels in brain and skeletal muscle of fasting nonpregnant wom…

AdultIntracellular Fluidmedicine.medical_specialtyPregnancy Trimester ThirdDiastolechemistry.chemical_elementBlood PressurePreeclampsiaAdenosine TriphosphatePre-EclampsiaPregnancyMagnesium deficiency (medicine)Internal medicineInternal MedicinemedicineHumansMagnesiumIonMuscle SkeletalNuclear Magnetic Resonance BiomolecularBrain ChemistryMagnesiumbusiness.industrySkeletal muscleFastingHydrogen-Ion Concentrationmedicine.diseasePreeclampsiaPathophysiologymedicine.anatomical_structureBlood pressureEndocrinologyMetabolismchemistryFemalebusinessMagnesium DeficiencyPregnancy disorder
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Diagnosis of pre-sarcopenia from a single selectional crosscut at C3 region, using CT scans before radiotherapy

2019

espanolProposito: el proposito de este estudio fue diagnosticar la presarcopenia en pacientes con cancer que no disponen de imagenes por tomografia computarizada (TC) a nivel abdominal mediante un metodo novedoso basado en cortes a nivel cervical. Material y metodos: se analizaron y se compararon mediante unidades la masa muscular y la masa muscular esqueletica en 37 pacientes con cancer de pulmon y neoplasias del aparato digestivo superior que incluian cortes en la TC de planificacion a nivel de C3 y L3. La presarcopenia se identifico de acuerdo con los puntos de corte establecidos actualmente: ≤ 41 cm2/m2 para mujeres, ≤ 43 cm2/m2 en hombres con un IMC ≤ 25 kg/m2 y ≤ 53 cm2/m2 en hombres …

AdultMale0301 basic medicineSarcopeniaLung NeoplasmsEsophageal Neoplasmsmedicine.medical_treatmentTomografiaMedicine (miscellaneous)Radioteràpia030209 endocrinology & metabolismComputed tomographyCohort Studies03 medical and health sciences0302 clinical medicineStomach NeoplasmsmedicineHumansC3Lung cancerCàncerCancerAgedRetrospective StudiesAged 80 and over030109 nutrition & dieteticsNutrition and DieteticsRadiotherapymedicine.diagnostic_testbusiness.industryMiddle Agedmedicine.diseaseSkeletal muscle massPancreatic NeoplasmsRadiation therapyL3SarcopeniaCT scansFemaleRadiotherapy treatmentTomography X-Ray ComputedbusinessNuclear medicine
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Heavy resistance exercise training and skeletal muscle androgen receptor expression in younger and older men

2010

Effects of heavy resistance exercise on serum testosterone and skeletal muscle androgen receptor (AR) concentrations were examined before and after a 21-week resistance training period. Seven healthy untrained young adult men (YT) and ten controls (YC) as well as ten older men (OT) and eight controls (OC) volunteered as subjects. Heavy resistance exercise bouts (5 × 10 RM leg presses) were performed before and after the training period. Muscle biopsies were obtained before and 1h and 48 h after the resistance exercise bouts from m.vastus lateralis (VL) to determine cross-sectional area of muscle fibers (fCSA) and AR mRNA expression and protein concentrations. No changes were observed in YC …

AdultMaleAgingmedicine.medical_specialtymedicine.drug_classClinical BiochemistryPhysical exerciseBiologyBiochemistryMuscle hypertrophyEndocrinologyReference ValuesInternal medicinemedicineHumansTestosteroneMuscle StrengthRNA MessengerMuscle Skeletalta315Molecular BiologyTestosteroneAgedPharmacologyReverse Transcriptase Polymerase Chain ReactionGene Expression ProfilingOrganic ChemistrySkeletal muscleResistance TrainingMiddle AgedAndrogenAndrogen receptorEndocrinologymedicine.anatomical_structureGene Expression RegulationReceptors AndrogenAgeingLean body massSteroids
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Calf Blood Compound (CFC) and Homeopathic Drug Induce Differentiation of Primary Human Skeletal Muscle Cells.

2019

AbstractThe use of injections to treat structural muscle injuries is controversially discussed. In our controlled in vitro study, we investigated the biological impact of Actovegin and Traumeel alone and in combination on primary human skeletal muscle cells. Cells were characterized by immunofluorescence staining for myogenic factor 5 (Myf5) and MyoD, and cultured with or without Actovegin and / or Traumeel. The effects of these agents were assayed by cell viability and gene expression of the specific markers MyoD, Myf5, neural adhesion molecule (NCAM), and CD31. Myotube formation was determined by myosin staining. Neither Actovegin nor Traumeel showed toxic effects or influenced cell viabi…

AdultMaleCell SurvivalMuscle Fibers SkeletalDown-RegulationPhysical Therapy Sports Therapy and RehabilitationHeme030204 cardiovascular system & hematologyPharmacologyMyoD03 medical and health sciences0302 clinical medicineIn vivoGene expressionMyosinmedicineHumansOrthopedics and Sports MedicineViability assayCells CulturedAgedMyoD ProteinMineralsDose-Response Relationship DrugChemistryPlant ExtractsSkeletal muscleCell Differentiation030229 sport sciencesMiddle Agedmusculoskeletal systemCD56 AntigenPlatelet Endothelial Cell Adhesion Molecule-1medicine.anatomical_structureNeural cell adhesion moleculeMYF5Myogenic Regulatory Factor 5International journal of sports medicine
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Mechanical characteristics and fiber composition of human leg extensor muscles.

1979

To investigate the influence of skeletal muscle fiber composition on the mechanical performance of human skeletal muscle under dynamic conditions, 34 physical education students with differing muscle fiber composition (M. vastus lateralis) were used as subjects to perform maximal vertical jumps on the force-platform. Two kinds of jumps were performed: one from a static starting position (SJ), the other with a preliminary counter-movement (CMJ). The calculated mechanical parameters included height of rise of center of gravity (h), average force (F), net impulse (NI) and average mechanical power (W). It was observed that the percentage of fast twitch fibers was significantly related (p less t…

AdultMaleLegMaterials scienceFast twitch musclePhysiologyMusclesWork (physics)Public Health Environmental and Occupational HealthSkeletal muscleGeneral MedicineAnatomyImpulse (physics)Biomechanical Phenomenamedicine.anatomical_structurePhysiology (medical)medicineReaction TimeHumansOrthopedics and Sports MedicineHuman legMuscle fibreFiber compositionMechanical energyBiomedical engineeringEuropean journal of applied physiology and occupational physiology
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Electromechanical delay in human skeletal muscle under concentric and eccentric contractions.

1979

In contraction of skeletal muscle a delay exists between the onset of electrical activity and measurable tension. This delay in electromechanical coupling has been stated to be between 30 and 100 ms. Thus, in rapid movements it may be possible for electromyographic (EMG) activity to have terminated before force can be detected. This study was designed to determine the dependence of the EMG-tension delay upon selected initial conditions at the time of muscle activation. The right forearms of 14 subjects were passively oscillated by a motor-driven dynamometer through flexion-extension cycles of 135 deg at an angular velocity of approximately equal to 0.5 rad/s. Upon presentation of a visual s…

AdultMaleLightPhysiologyMovementBrachioradialisIsometric exerciseConcentricBicepsPhysiology (medical)medicineEccentricHumansOrthopedics and Sports MedicinePhysicsMusclesPublic Health Environmental and Occupational HealthSkeletal muscleGeneral MedicineAnatomyElectrophysiologyElectrophysiologymedicine.anatomical_structuremedicine.symptomBiomedical engineeringMuscle contractionMuscle ContractionEuropean journal of applied physiology and occupational physiology
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Medial gastrocnemius muscle behavior during human running and walking.

2007

Utilization of elastic energy in the tendinous tissues (TT) of the human skeletal muscle may be task dependent. The present study was designed to investigate this problem by comparing the fascicle-TT interaction of the medial gastrocnemius muscle (MG) during ground contact of running and walking. Seven subjects ran and walked with a natural cadence. Ankle and knee joint angular data were recorded by electrogoniometers for estimating the entire MG muscle-tendon unit (MTU) length, together with the ground reaction forces. The MG fascicle length was measured by using the high-speed ultrasound image scanning during movements. The results showed that in running, after the rapid early fascicle st…

AdultMaleMaterials scienceMuscle RelaxationMuscle Fibers SkeletalBiophysicsMedial gastrocnemiusWalkingKnee JointSarcomereRunningmedicineHumansOrthopedics and Sports MedicineGround reaction forceMuscle SkeletalUltrasonographyLegElectromyographyRehabilitationSkeletal muscleAnatomyFasciclemedicine.anatomical_structureAnkleCadenceMuscle ContractionGaitposture
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Alterations of mechanical characteristics of human skeletal muscle during strength training

1983

To investigate the influence of strength training on the mechanical characteristics of human skeletal muscle, 14 male subjects went through training of combined heavy concentric and eccentric contractions three times a week for 16 weeks. The strength training program consisted mainly of dynamic exercises for leg extensors with loads of 80 to 120% of one maximum repetition. The force-time curves produced during various vertical jumps were the basis for calculation of various mechanical parameters. In addition to a great increase (p less than 0.001) in maximal isometric force, heavy resistance strength training also caused significant (p less than 0.05-0.01) increases in heights and in variou…

AdultMaleMaterials sciencePhysiologyStrength trainingEccentric contractionsSquatIsometric exerciseConcentricSports MedicinePhysiology (medical)medicineHumansOrthopedics and Sports MedicineLegPhysical Education and TrainingForce levelMusclesPublic Health Environmental and Occupational HealthSkeletal muscleMuscle mechanicsGeneral MedicineAnatomyElasticityBiomechanical Phenomenamedicine.anatomical_structureBiomedical engineeringEuropean Journal of Applied Physiology and Occupational Physiology
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Warm underwater water-jet massage improves recovery from intense physical exercise

1995

The effects of warm underwater water-jet massage on neuromuscular functioning, selected biochemical parameters (serum creatine kinase, lactic dehydrogenase, serum carbonic anhydrase, myoglobin, urine urea and creatinine) and muscle soreness were studied among 14 junior track and field athletes. Each subject spent, in a randomized order, two identical training weeks engaged in five strength/power training sessions lasting 3 days. The training weeks differed from each other only in respect of underwater water-jet massage treatments. These were used three times (20 min each) during the treatment week and not used during the control week. During the treatment week continuous jumping power decre…

AdultMaleMuscle tissuemedicine.medical_specialtyHot TemperatureAdolescentPhysiologymedicine.medical_treatmentPhysical exercisemedicine.disease_causechemistry.chemical_compoundJumpingPhysiology (medical)medicineHumansUreaOrthopedics and Sports MedicineMuscle SkeletalHydrotherapyCreatine KinaseExerciseCarbonic AnhydrasesHydrotherapyMassageCreatinineMassageL-Lactate DehydrogenaseMyoglobinbusiness.industryPublic Health Environmental and Occupational HealthSkeletal muscleGeneral MedicineKineticsmedicine.anatomical_structurechemistryMyoglobinCreatinineAnesthesiaPhysical therapyFemalebusinessSportsEuropean Journal of Applied Physiology and Occupational Physiology
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Focal myositis of the temporal muscle

1993

Focal myositis is a rare inflammatory disease of the skeletal muscle that may involve any part of the body. We present a 19-year-old man with a short history of a painful pseudotumor in the right temporal region. MRI pictures showed a swollen right temporal muscle and muscle biopsy revealed the characteristic histological and immunocytochemical findings of polymyositis.

AdultMalePathologymedicine.medical_specialtyPhysiologyBiopsyTemporal musclePolymyositisNecrosisCellular and Molecular NeurosciencePhysiology (medical)BiopsymedicineHumansMyositisMuscle biopsyMyositismedicine.diagnostic_testbusiness.industryMusclesSkeletal muscleHistologyMagnetic resonance imagingAnatomymedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureNeurology (clinical)businessMuscle & Nerve
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