Search results for "slip"
showing 10 items of 471 documents
Influence of obesity on atherogenic dyslipidemia in women with polycystic ovary syndrome.
2013
Background Obesity is known to underlie, at least partially, dyslipidemia in polycystic ovary syndrome (PCOS), but it is unclear whether PCOS status per se increases the risk of alterations of lipoprotein subfractions, which differ in size and atherogenic potential. Our objective was to evaluate whether PCOS influences lipoprotein profile and LDL and HDL subfractions and to study the impact of obesity on these parameters. Materials and methods This was a case–control study conducted in an academic medical centre. The study population consisted of 54 women of fertile age with PCOS and 60 controls adjusted for age and BMI. Biochemical lipid profile and LDL and HDL lipoprotein subfractions (me…
How should we manage atherogenic dyslipidemia in women with polycystic ovary syndrome?
2007
Despite their young age, women with polycystic ovary syndrome (PCOS) have increased cardiovascular risk. Besides normal concentrations of low-density lipoprotein (LDL) cholesterol, dyslipidemia is very common and includes elevated triglyceride levels and low high-density lipoprotein cholesterol concentrations. Recent findings also showed that women with PCOS have qualitative LDL alterations, with increased levels of atherogenic small, dense LDL particles. Such lipid abnormalities constitute a common form of dyslipidemia, the so-called atherogenic lipoprotein phenotype (ALP), associated with a greater cardiovascular risk. Weight reduction and increased physical activity may constitute first-…
Atherogenic forms of dyslipidaemia in women with polycystic ovary syndrome.
2009
OBJECTIVE: Dyslipidaemia is very common in patients with polycystic ovary syndrome (PCOS) but, beyond plasma lipids, atherogenic lipoprotein (Lp) and apolipoprotein (apo) alterations are still ill defined. DESIGN: We measured concentrations of apoB, Lp(a) and small, dense low-density lipoprotein (LDL) in 42 patients with PCOS [age: 28 +/- 7 years, body mass index (BMI): 27 +/- 5 kg/m(2)] vs. 37 age- and BMI-matched healthy controls. METHODS: Elevated Lp(a) levels considered were those > 30 mg/dl while elevated apoB concentrations were those > 100 g/l. RESULTS: Polycystic ovary syndrome showed increased triglycerides levels (p = 0.0011) and lower high-density lipoprotein (HDL)-cholesterol co…
Differences in dyslipidemia between American and Italian women with polycystic ovary syndrome.
2008
Abstract BACKGROUND: Dyslipidemia is a common metabolic complication in polycystic ovary syndrome (PCOS). The aim of this study was to determine if differences exist in dyslipidemia in women with PCOS from different ethnic and geographical backgrounds. METHODS: This retrospective study evaluated the serum fasting lipid profiles of 106 women with PCOS from the United States and 108 women with PCOS from Italy evaluated at endocrinology clinics. RESULTS: American women had higher mean body mass index than Italian women (36.1+/-8.6 vs 28.1+/-5.8 kg/m2, p<0.01). Low HDL-cholesterol was the most prevalent lipid abnormality in both populations. U.S. women had higher mean levels of serum total chol…
Postmarketing nutrivigilance safety profile: a line of dietary food supplements containing red yeast rice for dyslipidemia
2021
IntroductionIn the absence of a European standardized postmarketing food supplement surveillance system (nutrivigilance), some member states and companies have developed their own approaches to monitoring potential adverse reactions to secure a high level of product safety. This paper describes the use of a nutrivigilance system in monitoring the incidence of spontaneously reported suspected adverse reactions associated with food supplements containing red yeast rice (RYR).Material and methodsWe report the data from a widely used product marketed under the trademark Armolipid/Armolipid Plus. Postmarketing information was collected in a voluntary nutrivigilance system established by the manu…
Relationship Between the Apolipoprotein E Genotype and LDL Particle Size in Patients With Obstructive Sleep Apnea.
2016
Obstructive sleep apnea (OSA) is associated with dyslipidemia and increased cardiovascular risk. We assessed the effects of apolipoprotein E ( APOE) genotype on low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particle size and lipid subclasses (separated by gradient gel electrophoresis) in patients with OSA. Stable patients (n = 181) prospectively recruited underwent full polysomnography. Both LDL particle size and LDL I proportion were reduced from ∊3∊3 homozygotes to ∊2 carriers and to ∊4 carriers (analysis of variance: P = .024; P = .040, respectively); carriers of the ∊4 allele of the APOE genotype had significantly lower LDL particle size and LDL I proportion compared…
Porous medium equation with absorption and a nonlinear boundary condition
2002
where is a bounded domain with smooth boundary, @=@ is the outer normal derivative, m ? 1; p; and q are positive parameters and u0 is in L∞( ). Problems of this form arise in mathematical models in a number of areas of science, for instance, in models for gas or :uid :ow in porous media [3] and for the spread of certain biological populations [13]. In the semilinear case (that is for m=1), there is an extensive literature about global existence and blow-up results for this type of problems, see among others, [5,9,16] and the literature therein. For the degenerate case (that is for m = 1), with a nonlinear boundary condition, local existence and uniqueness of weak solutions which are limit o…
Pottery decoration in the Neolithic of Kaf Taht el-Ghar (Tetouan, Morocco). AGRIWESTMED Works 2012
2021
Presentamos el estudio de los restos cerámicos de la fase neolítica de Kaf Taht el-Ghar (Mechrouha, Tetuán, Marruecos), enfocado principalmente en el análisis de técnicas y patrones decorativos. Ello cuenta con el interés añadido de corresponder, en su fase antigua, a las cerámicas asociadas a las primeras evidencias de agricultura y ganadería en el Magreb Occidental, encuadradas en el tercer cuarto del VI milenio cal AC. En dichas decoraciones dominan impresiones variadas, en particular las realizadas con concha estriada y lisa, peine y de cypraea. El uso de tales técnicas podría incluir estas primeras producciones cerámicas dentro del mundo impresso-cardial de la Europa mediterránea centr…
Active faulting and continental slope instability in the Gulf of Patti (Tyrrhenian side of NE Sicily, Italy): a field, marine and seismological joint…
2016
The Gulf of Patti and its onshore sector represent one of the most seismically active regions of the Italian Peninsula. Over the period 1984–2014, about 1800 earthquakes with small-to-moderate magnitude and a maximum hypocentral depth of 40 km occurred in this area. Historical catalogues reveal that the same area was affected by several strong earthquakes such as the Mw = 6.1 event in April 1978 and the Mw = 6.2 one in March 1786 which have caused severe damages in the surrounding localities. The main seismotectonic feature affecting this area is represented by a NNW–SSE trending right-lateral strike-slip fault system called ‘‘Aeolian–Tindari–Letojanni’’ (ATLFS) which has been interpreted a…
Evidence of positive tectonic inversion in the north-central sector of the Sicily Channel (Central Mediterranean)
2016
In order to unravel the tectonic evolution of the north-central sector of the Sicily Channel (Central Mediterranean), a seismo-stratigraphic analysis of single- and multi-channel seismic reflection profiles has been carried out. This allowed to identify, between 20 and 50 km offshore the central-southern coast of Sicily, a ~80-km-long deformation belt, characterized by a set of WNW–ESE to NW–SE fault segments showing a poly-phasic activity. Within this belt, we observed: i) Miocene normal faults reactivated during Zanclean–Piacenzian time by dextral strike-slip motion, as a consequence of the Africa–Europe convergence; ii) releasing and restraining bend geometries forming well-developed pul…