Search results for "slip"
showing 10 items of 471 documents
Nutraceuticals and dyslipidaemia: Beyond the common therapeutics
2014
Dyslipidaemia accelerates the atherosclerotic process and its morbid consequences; statins represent the evidence-based treatment of choice for reducing low-density lipoprotein cholesterol levels and decreasing cardiovascular events. Unfortunately, statins are frequently not available for several reasons, including intolerance, side effects or, simply, patient preference. Nutraceuticals and functional food ingredients that are beneficial to vascular health may represent useful compounds that are able to reduce the overall cardiovascular risk induced by dyslipidaemia by acting parallel to statins or as adjuvants in case of failure or in situations where statins cannot be used. The mechanisms…
Consenso Delphi sobre el diagnóstico y manejo de la dislipidemia en pacientes con enfermedad renal crónica: análisis post-hoc del estudio DIANA
2016
Resumen Antecedentes y objetivos: Este estudio post hoc analizó la percepción de la importancia de la enfermedad renal crónica (ERC) en el cribado de la dislipidemia y en la elección del tratamiento con estatinas entre médicos de Atención Primaria (MAP) y otras especialidades mediante cuestionario Delphi. Métodos: El cuestionario incluyó 4 bloques de preguntas alrededor del paciente dislipémico con alteración del metabolismo hidrocarbonado. Aquí se presentan los resultados relacionados con la consideración de la ERC en el cribado y la elección de la estatina. Resultados: De los 497 expertos incluidos, el 58% eran MAP y el 42%, especialistas (35, el 7%, nefrólogos). Hubo consenso en realizar…
Consenso Delphi sobre el diagnóstico y manejo de la dislipidemia en pacientes con enfermedad renal crónica: análisis post-hoc del estudio DIANA
2016
ResumenAntecedentes y objetivosEste estudio post hoc analizó la percepción de la importancia de la enfermedad renal crónica (ERC) en el cribado de la dislipidemia y en la elección del tratamiento con estatinas entre médicos de Atención Primaria (MAP) y otras especialidades mediante cuestionario Delphi.MétodosEl cuestionario incluyó 4bloques de preguntas alrededor del paciente dislipémico con alteración del metabolismo hidrocarbonado. Aquí se presentan los resultados relacionados con la consideración de la ERC en el cribado y la elección de la estatina.ResultadosDe los 497 expertos incluidos, el 58% eran MAP y el 42%, especialistas (35, el 7%, nefrólogos). Hubo consenso en realizar un cribad…
A NEXT GENERATION SEQUENCING APPROACH FOR MOLECULAR DIAGNOSIS OF MONOGENIC DYSLIPIDEMIAS
The therapeutic modulation of atherogenic dyslipidemia and inflammatory markers in the metabolic syndrome: what is the clinical relevance?
2008
The metabolic syndrome consists of a constellation of clinical and biochemical risk factors that cluster together and heighten the risk for atherogenesis, cardiovascular diseases, and diabetes. Established risk cardiovascular factors like hypertension, atherogenic dyslipidaemia, and glucose intolerance occur in the setting of insulin resistance and central adiposity, with genetic and environmental influences modulating the ultimate risk. Chronic insults to the endothelium take its toll in the form of silent as well as clinically evident cardiovascular events. The cellular and vascular accompaniments have shed some light into the underlying pathophysiology. Heightened, low-grade inflammatory…
An Analytical Tire Model with Flexible Carcass for Combined Slips
2014
Published version of an article in the journal: Mathematical Problems in Engineering. Also available from the publisher at: http://dx.doi.org/10.1155/2014/397538 The tire mechanical characteristics under combined cornering and braking/driving situations have significant effects on vehicle directional controls. The objective of this paper is to present an analytical tire model with flexible carcass for combined slip situations, which can describe tire behavior well and can also be used for studying vehicle dynamics. The tire forces and moments come mainly from the shear stress and sliding friction at the tread-road interface. In order to describe complicated tire characteristics and tire-roa…
Calculation of Turbo-Roundabouts with Slip Lanes
2013
A turbo roundabout is a particular type of roundabout where all lanes are bounded by traffic signs and by non-mountable curbs installed at entering and circulating lanes. Turbo roundabouts also have a very particular shape to accomplish the splitting of traffic streams and to prevent cars weaving through. These aspects make turbo-roundabouts more appropriate than roundabouts when a higher level of safety has to be guaranteed, particularly in presence of relevant pedestrian and two-wheels traffic volumes. Only in some traffic conditions, turbo roundabouts can offer higher capacities than conventional double-lanes roundabouts, so if more capacity must be guarantee a bypass lane can be added t…
Free-surface shape in unbaffled stirred vessels: Experimental study via digital image analysis
2013
There is a growing interest in using unbaffled stirred tanks for addressing a number of processing needs such as low shear damage (sensitive biocultures), low attrition (solid–liquid applications), deep-cleaning/sterilization (pharmaceutical applications). The main feature of uncovered, unbaffled stirred tanks is highly swirling motion of the fluid that results in a deformation of the free liquid surface. At sufficiently high agitation speeds the resulting whirlpool reaches the impeller and gives rise to a gas–liquid dispersion, so leading to the formation of a dispersion without the use of gas-sparger; the so-called self-inducing operation of the vessel. In this work, digital image analysi…
Cross-Flow Turbine Design For Energy Production And Discharge Regulation
2015
Cross-flow turbines are very efficient and cheap turbines that allow a very good cost/benefit ratio for energy production located at the end of conduits carrying water from a water source to a tank. In this paper a new design procedure for a cross-flow turbine working with a variable flow rate is proposed. The regulation of the head immediately upstream the turbine is faced by adopting a shaped semicircular segment moving around the impeller. The maximum efficiency of the turbine is attained by setting the velocity of the particles entering the impeller at about twice the velocity of the rotating system at the impeller inlet. If energy losses along the pipe are negligible, the semicircular …
Finite element modelling of slipage between FRP rebar and concrete in pull-out test
2014
The paper presents numerical results of direct pull-out test of glass fiber-reinforced polymer (GFRP) rebars embedded in concrete. Rebars of three different cross-sections are considered: circular without longitudinal ribs and with two and four ribs. The design analyses of the rebar configurations embedded in concrete are investigated by the 3D finite element method (FEM), which takes into account the non-linearity using ANSYS software. The results of the numerical model with two ribs were compared with the experimental results. Then, the effect of different rebar geometries to the load-slip pull-out curves was studied. It is concluded that the influence of rib height and width on the pull-…