Search results for "soin"

showing 10 items of 600 documents

ANNELATED ISOINDOLES WITH POTENT ANTITUMOR ACTIVITY

2009

ANNELATED ISOINDOLESSettore CHIM/08 - Chimica Farmaceutica
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Do ventilatory parameters influence outcome in patients with severe acute respiratory infection? Secondary analysis of an international, multicentre1…

2021

Purpose: To investigate the possible association between ventilatory settings on the first day of invasive mechanical ventilation (IMV) and mortality in patients admitted to the intensive care unit (ICU) with severe acute respiratory infection (SARI). Materials and methods: In this pre-planned sub-study of a prospective, multicentre observational study, 441 patients with SARI who received controlled IMV during the ICU stay were included in the analysis. Results: ICU and hospital mortality rates were 23.1 and 28.1%, respectively. In multivariable analysis, tidal volume and respiratory rate on the first day of IMV were not associated with an increased risk of death; however, higher driving pr…

ARDSSoins intensifs réanimationmedicine.medical_treatmentAirway pressuresPEEP positive end-expiratory pressureCritical Care and Intensive Care Medicinelaw.inventionHypoxemiaCohort StudiesPositive-Pressure RespirationMechanical ventilationSARI severe acute respiratory infectionlawHospital MortalityProspective StudiesIQR interquartile rangesProspective cohort studyRCT randomized controlled trialTidal volumeSOFA Sequential Organ Failure AssessmentSAPS Simplified Acute Physiology ScoreIntensive care unitVCV volume-controlled ventilationHIV human immunodeficiency virusIntensive Care UnitsIC GLOSSARI Intensive Care Global Study on Severe Acute Respiratory Infectionmedicine.symptomCohort studyLOS length of staymedicine.medical_specialtyVt tidal volumeCOPD Chronic obstructive pulmonary diseaseNYHA New York Heart Association.PCV pressure-controlled ventilationArticleInternal medicineICU Intensive Care UnitSIMV Synchronized intermittent mandatory ventilationmedicineTidal VolumeHumansDP driving pressurePEEPARDS acute respiratory distress syndromeMechanical ventilationbusiness.industryOdds ratioPneumoniaPlateau pressuremedicine.diseaseRespiration ArtificialVILI ventilator induced lung injuryCI confidence intervalOR odds ratioIMV invasive mechanical ventilationCPAP continuous positive airway pressureARDSbusinessSD standard deviationECMO extracorporeal membrane oxygenationPBW predicted body weightPplat plateau pressure
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Le bon soignant en soins palliatifs et les définitions du patient

2010

National audience; L'hôpital n'est pas un milieu homogène : les pratiques et les représentations professionnelles divergent d'un service à l'autre, mais se présentent toutes comme étant au service du soin. Dès lors, chaque service défend, entre autres, une définition de ce que sont un bon soignant et un bon patient. L'auteur, sociologue, aborde ici la figure du « bon soignant » en soins palliatifs puis, dans un second temps, passe rapidement sur la figure du « bon patient », avant de s'attarder sur celles construites par les professionnels, leur permettant de bien faire leur travail, à savoir deux grands types de patients : le mourant et l'agonisant.

Accompagnement mourant[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/Lawsoins palliatifs[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieSociologieReprésentation maladie[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologieMalade incurablebon soignantImage professionnel[ SHS.DROIT ] Humanities and Social Sciences/Law
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Semantic structures of timbre emerging from social and acoustic descriptions of music

2011

The perceptual attributes of timbre have inspired a considerable amount of multidisciplinary research, but because of the complexity of the phenomena, the approach has traditionally been confined to laboratory conditions, much to the detriment of its ecological validity. In this study, we present a purely bottom-up approach for mapping the concepts that emerge from sound qualities. A social media ( http://www.last.fm ) is used to obtain a wide sample of verbal descriptions of music (in the form of tags) that go beyond the commonly studied concept of genre, and from this the underlying semantic structure of this sample is extracted. The structure that is thereby obtained is then evaluated th…

Acoustics and UltrasonicsComputer scienceEcological validityMusic information retrievalsointiväriSpeech recognitionmusiikkisosiaalinen mediacomputer.software_genreTimbreSimilarity (psychology)Social media.Music information retrievalElectrical and Electronic EngineeringSet (psychology)Structure (mathematical logic)Music psychologybusiness.industryNatural language processingVector-based semantic analysisDegree (music)acoustic featuresakustiset piirteetArtificial intelligencebusinessTimbrecomputerNatural language processingEURASIP Journal on Audio, Speech, and Music Processing
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Enhancing the efficacy of integrative improvisational music therapy in the treatment of depression : study protocol for a randomised controlled trial

2019

Abstract Background Depression is among the leading causes of disability worldwide. Not all people with depression respond adequately to standard treatments. An innovative therapy that has shown promising results in controlled trials is music therapy. Based on a previous trial that suggested beneficial effects of integrative improvisational music therapy (IIMT) on short and medium-term depression symptoms as well as anxiety and functioning, this trial aims to determine potential mechanisms of and improvements in its effects by examining specific variations of IIMT. Methods/design A 2 × 2 factorial randomised controlled trial will be carried out at a single centre in Finland involving 68 adu…

AdultMalemasennusTime FactorsAdolescentEmotionsmusiikkiterapiaAnxietyresonanssiclinical improvisationStudy ProtocolYoung AdultIntegrative psychotherapyhengitysHumansahdistusimprovisointiLungFinlandRandomized Controlled Trials as TopicResonance frequency breathinglcsh:R5-920DepressionRespirationClinical improvisationBiofeedback PsychologyMiddle AgedpsykoterapiaAffectTreatment OutcomedepressionAuditory PerceptionkotitehtävätFemaleHomeworkMusic therapylcsh:Medicine (General)resonance frequency breathingintegrative psychotherapy
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Étude comparative des politiques éducatives d'inclusion en France et en Afrique subsaharienne

2010

Ce travail présente un projet de recherche, en cours de réalisation, sur la comparaison entre les politiques éducatives d'inclusion des enfants en situation d'handicap en France et dans deux pays d'Afrique subsaharienne : l'Éthiopie et le Cameroun. Il s'intéresse à l'étude mécanismes mis en place par ces politiques nationales pour favoriser l'insertion, le développement et la réussite scolaire de ces enfants. Les résultats de l'étude exploratoire réalisée en Éthiopie ont montré que l'appropriation du concept d'éducation inclusive et la mise en ouvre effective d'une politique d'inclusion connaissent des limites, en dépit de la prise en compte des besoins éducatifs spéciaux dans le plan de dé…

AfriqueComparaison internationaleCameroun[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationÉthiopiePolitique éducativeHandicapÉlève[ SHS.EDU ] Humanities and Social Sciences/EducationÉducation inclusiveFranceBesoin éducatif
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In-Service teacher education in Kenya

1984

International audience

Afrique[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationCoût de l'enseignementBesoin de formationSystème éducatifKenyaComputingMilieux_MISCELLANEOUSFormation continue des enseignantsEnseignement primaire
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Enhancement of retention predictions in reversed-phase liquid chromatography using reference compounds

2004

Abstract The use of reference compounds to correct errors associated with the preparation of mobile phase is studied, in order to enhance modelling of retention for optimisation purposes in reversed-phase liquid chromatography. The method fits individual retention models for a set of reference compounds, which are present in all injections. In second step, mobile-phase composition is corrected for each chromatogram, according to the fitted models of the reference compounds. The enhanced precision provided by the large number of replicates for the reference compounds is partially propagated to the retention models of the analytes. The approach is assayed in the separation of amino acids, aft…

AnalyteChromatographyIsoindolesChemistryAnalytical chemistryReversed-phase chromatographyBiochemistryAnalytical Chemistrychemistry.chemical_compoundReagentPhase (matter)Environmental ChemistryDerivatizationAcetonitrileSpectroscopyPhthalaldehydeAnalytica Chimica Acta
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Automatisoitu GUI-testaus mobiiliapplikaatioissa

2017

Mobiiliapplikaatioiden määrä on kasvanut viime vuosina paljon, joten niiden laadunvalvonta on tärkeää. Tässä tutkielmassa etsitään automatisoidusta GUI-testauksesta piirteitä, jotka auttaisivat mobiilitestausta kohtaamaan alan kasvavat vaatimukset. Lupaavimpia ratkaisuja tarjoavat testityökalut, jotka yhdistävät erilaisia testaustapoja tai toimivat useilla alustoilla. The number of mobile applications has grown much over the past years, making quality control for apps important. In this thesis traits that help mobile testing face the growing demands of the industry are looked for from automated GUI testing. The test tools that seem most promising combine different ways of testing or work on…

AndroidGUI-testausmobiilitestausautomatisointi
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Pyrano[2,3-e]isoindol-2-ones, new angelicin heteroanalogues

2009

A convenient synthesis of the pyrano[2,3-e]isoindol-2-one ring system, an heteroanalogue of angelicin, is reported. Our synthetic approach consists of the annelation of the pyran ring on the isoindole moiety using 5-dialkylamino- or 5-hydroxymethylene intermediates as building blocks. The photoantiproliferative activity of the new derivatives was studied. Some of them bearing the benzyl group at the 8 position were active with IC(50) in the micromolar range. Cell cytotoxicity involves apoptosis, alteration of cell cycle profile and membrane photodamage.

AnnulationPyrano-isoindolesStereochemistryChemistry PharmaceuticalClinical BiochemistryPharmaceutical ScienceApoptosisIsoindolesRing (chemistry)BiochemistryChemical synthesisInhibitory Concentration 50Jurkat CellsStructure-Activity Relationshipchemistry.chemical_compoundAngelicinCell Line TumorFurocoumarinsDrug DiscoveryHumansMoietyMolecular BiologyPyransMolecular StructurePyrano-isoindoleChemistryPhotochemotherapeutic activityOrganic ChemistryPyrano-isoindoles; Angelicin heteroanalogues; Photochemotherapeutic activity; ApoptosisSettore CHIM/08 - Chimica FarmaceuticaAngelicin heteroanaloguesOxygenModels ChemicalPyranDrug DesignBenzyl groupMolecular MedicineK562 CellsIsoindoleAngelicin heteroanalogueBioorganic & Medicinal Chemistry Letters
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