Search results for "solu"
showing 10 items of 7577 documents
The new world of biosimilars: what diabetologists need to know about biosimilar insulins
2010
Biosimilar pharmaceuticals are emerging as patent protection on the original biopharmaceutical products expires. However, biopharmaceuticals are particularly complex molecules, and biosimilar insulins present special challenges. In part this reflects their structure and chemical modification after synthesis to attain a biologically active form. Their therapeutic window is narrow and the accuracy of their dosing is highly dependent on the formulation and quality of the administration device. For these reasons, the European Medicines Agency has issued stringent guidelines that must be fulfilled in order to receive approval as a biosimilar soluble insulin. Prescribers should therefore consider…
Early and Later Predictors of Outcome in Brief Therapy: The Role of Real Relationship
2012
Objectives The study examined whether clients who continued longer in brief therapy reported stronger associations of real relationship and working alliance with therapy outcome than clients who received very brief treatment. It also examined whether real relationship and working alliance assessed early in treatment predicted outcome differently from that assessed later in therapy. Method Fifty clients (32 women; Mage = 22.3 years) were recruited from a university counseling center. Thirty-two clients (very brief therapy) completed the post-third session assessment of real relationship and working alliance, and 18 (brief therapy) had both the third and eighth assessment. Results The real re…
Magnetic properties of Co–Al, Ni–Al, and Mg–Al hydrotalcites and the oxides formed upon their thermal decomposition
2002
The magnetic behaviour of Co–Al, Ni–Al, and Mg–Al hydrotalcites (HTlc) with a M2+/Al3+ molar ratio of 3 and carbonates in the interlayer, as well as the mixed oxides obtained after calcination at 823 K for 5 h, has been investigated by DC and AC magnetic susceptibility measurements and isothermal magnetisation. The samples were also characterised by ICP-OES and XRD. The magnetic measurements show that Co–Al and Ni–Al HTlcs behave as ferromagnets, with ordering temperatures of approximately 6–7 K in both cases, and displaying hysteresis loops at 2 K with coercive fields of 4.2 and 5.5 mT, respectively, whereas the Mg–Al-HTlc shows the expected diamagnetic behaviour. A solid solution of cobal…
Local thermal equilibrium and ideal gas Stephani universes
2005
The Stephani universes that can be interpreted as an ideal gas evolving in local thermal equilibrium are determined. Five classes of thermodynamic schemes are admissible, which give rise to five classes of regular models and three classes of singular models. No Stephani universes exist representing an exact solution to a classical ideal gas (one for which the internal energy is proportional to the temperature). But some Stephani universes may approximate a classical ideal gas at first order in the temperature: all of them are obtained. Finally, some features about the physical behavior of the models are pointed out.
Review of thermal infrared applications and requirements for future high-resolution sensors
2016
High-resolution thermal infrared (TIR) remote sensing has a wide range of applications. In this paper, we describe the different applications and requirements identified in a literature review and during a consultation meeting with researcher experts in different fields. As a result, more than 30 applications were identified within three different fields: 1) land and solid Earth; 2) health and hazards; and 3) security and surveillance. A complete set of requirements (spatial, temporal, and radiometric resolution, algorithms used, and supporting data, among others) for each application is also provided. The results presented in this paper provide useful information to enhance the importance …
Minimum configuration of thermal infrared bands for land surface temperature and emissivity estimation in the context of potential future missions
2014
Abstract A number of applications rely on the availability of high resolution TIR data, both in terms of spatial and temporal resolution, as well as in terms of spectral configuration. A consensus exists among the thermal community regarding the lack of such a kind of data, since only one operational sensor is currently providing multispectral TIR data at high spatial resolution (the case of ASTER, at 90 m spatial resolution and a 16-day revisit time). In this paper we propose a minimum multispectral configuration to allow the retrieval of both land surface temperature (LST) and emissivity ( e ) from thermal infra-red (TIR) data. For this purpose, we propose a minimum configuration based on…
Land Surface Temperature Retrieval Methods From Landsat-8 Thermal Infrared Sensor Data
2014
The importance of land surface temperature (LST) retrieved from high to medium spatial resolution remote sensing data for many environmental studies, particularly the applications related to water resources management over agricultural sites, was a key factor for the final decision of including a thermal infrared (TIR) instrument on board the Landsat Data Continuity Mission or Landsat-8. This new TIR sensor (TIRS) includes two TIR bands in the atmospheric window between 10 and 12 $\mu\hbox{m}$ , thus allowing the application of split-window (SW) algorithms in addition to single-channel (SC) algorithms or direct inversions of the radiative transfer equation used in previous sensors on board …
Effect of Isovalent Substitution on the Thermoelectric Properties of the Cu2ZnGeSe4–xSx Series of Solid Solutions
2013
Knowledge of structure–property relationships is a key feature of materials design. The control of thermal transport has proven to be crucial for the optimization of thermoelectric materials. We report the synthesis, chemical characterization, thermoelectric transport properties, and thermal transport calculations of the complete solid solution series Cu_2ZnGeSe_(4–x)S_x (x = 0–4). Throughout the substitution series a continuous Vegard-like behavior of the lattice parameters, bond distances, optical band gap energies, and sound velocities are found, which enables the tuning of these properties adjusting the initial composition. Refinements of the special chalcogen positions revealed a chang…
Resolving the true band gap of ZrNiSn half-Heusler thermoelectric materials
2015
N-type XNiSn (X = Ti, Zr, Hf) half-Heusler (HH) compounds possess excellent thermoelectric properties, which are believed to be attributed to their relatively high mobility. However, p-type XNiSn HH compounds have poor figures of merit, zT, compared to XCoSb compounds. This can be traced to the suppression of the magnitude of the thermopower at high temperatures. E_g = 2eS_(max)T_(max) relates the band gap to the thermopower peak. However, from this formula, one would conclude that the band gap of p-type XNiSn solid solutions is only one-third that of n-type XNiSn, which effectively prevents p-type XNiSn HHs from being useful thermoelectric materials. The study of p-type HH Zr_(1−x)Sc_xNiSn…
POSS-tetraalkylammonium salts: A new class of ionic liquids
2012
A series of new polyhedral oligomeric silsesquioxane ionic liquids (POSS-ILs) based on the trimethylpropylammonium dielectric constants, which, conversely, display slight differences originating from the nature of the anions. The long alkyl-chain substituents on the POSS core infer on this series of ILs an overall hydrophobic character and solution properties comparable to those of classic cationic surfactants, resulting in an effective extractant capability of polyanions from aqueous solutions. Their solution diffusion properties, as investigated by room-temperature dynamic light scattering, solution conductivity, density, and osmometric measurements, do not provide evidence for the occurr…