Search results for "soma"
showing 10 items of 2624 documents
Genome architecture enables local adaptation of Atlantic cod despite high connectivity
2017
Adaptation to local conditions is a fundamental process in evolution; however, mechanisms maintaining local adaptation despite high gene flow are still poorly understood. Marine ecosystems provide a wide array of diverse habitats that frequently promote ecological adaptation even in species characterized by strong levels of gene flow. As one example, populations of the marine fish Atlantic cod (Gadus morhua) are highly connected due to immense dispersal capabilities but nevertheless show local adaptation in several key traits. By combining population genomic analyses based on 12K single-nucleotide polymorphisms with larval dispersal patterns inferred using a biophysical ocean model, we show…
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs)
2020
[Image: see text] Translational readthrough-inducing drugs (TRIDs) rescue the functional full-length protein expression in genetic diseases, such as cystic fibrosis, caused by premature termination codons (PTCs). Small molecules have been developed as TRIDs to trick the ribosomal machinery during recognition of the PTC. Herein we report a computational study to identify new TRID scaffolds. A pharmacophore approach was carried out on compounds that showed readthrough activity. The pharmacophore model applied to screen different libraries containing more than 87000 compounds identified four hit-compounds presenting scaffolds with diversity from the oxadiazole lead. These compounds have been s…
Partitioning of nitrogen during melting and recycling in subduction zones and the evolution of atmospheric nitrogen
2019
Abstract The subduction of sediment connects the surface nitrogen cycle to that of the deep Earth. To understand the evolution of nitrogen in the atmosphere, the behavior of nitrogen during the subduction and melting of subducted sediments has to be estimated. This study presents high-pressure experimental measurements of the partitioning of nitrogen during the melting of sediments at sub-arc depths. For quantitative analysis of nitrogen in minerals and glasses, we calibrated the electron probe micro-analyzer on synthetic ammonium feldspar to measure nitrogen concentrations as low as 500 μg g−1. Nitrogen abundances in melt and mica are used together with mass balance calculations to determi…
Geochemistry of Noble Gases and CO2 in Fluid Inclusions From Lithospheric Mantle Beneath Wilcza Góra (Lower Silesia, Southwest Poland)
2018
Knowledge of the products originating from the subcontinental lithospheric mantle (SCLM) is crucial for constraining the geochemical features and evolution of the mantle. This study investigated the chemistry and isotope composition (noble gases and CO2 ) of fluid inclusions (FI) from selected mantle xenoliths originating from Wilcza Góra (Lower Silesia, southwest Poland), with the aim of integrating their petrography and mineral chemistry. Mantle xenoliths are mostly harzburgites and sometimes bear amphiboles, and are brought to the surface by intraplate alkaline basalts that erupted outside the north-easternmost part of the Eger (Ohře) Rift in Lower Silesia. Olivine (Ol) is classified int…
Cretaceous ultrapotassic magmatism from the Sava-Vardar Zone of the Balkans
2020
Highlights • Geochemically diverse Late Cretaceous small-volume magmatism in the Sava-Vardar Zone. • Late Cretaceous ultrapotassic lava, equivalent of minette and kersantite. • Magma derivation from a LREE and K enriched, garnet-bearing anciently metasomatized mantle source. • Magmatism occurred either in a fore-arc setting or is associated with transtensional tectonics. Abstract Late Cretaceous global plate reorganization associated with the inception of counterclockwise rotation of Africa relative to Europe initiated in the Balkan region small-volume magmatism of diverse geochemical signature along the enigmatic Sava-Vardar Zone. We study a Late Cretaceous lamprophyric sill in Ripanj vill…
Phlogopite-pargasite coexistence in an oxygen reduced spinel-peridotite ambient
2021
AbstractThe occurrence of phlogopite and amphibole in mantle ultramafic rocks is widely accepted as the modal effect of metasomatism in the upper mantle. However, their simultaneous formation during metasomatic events and the related sub-solidus equilibrium with the peridotite has not been extensively studied. In this work, we discuss the geochemical conditions at which the pargasite-phlogopite assemblage becomes stable, through the investigation of two mantle xenoliths from Mount Leura (Victoria State, Australia) that bear phlogopite and the phlogopite + amphibole (pargasite) pair disseminated in a harzburgite matrix. Combining a mineralogical study and thermodynamic modelling, we predict …
Whole-rock Nd–Hf isotopic study of I-type and peraluminous granitic rocks from the Chinese Altai: Constraints on the nature of the lower crust and te…
2017
Abstract The nature of the lower crust and tectonic setting of the Chinese Altai in the early to middle Paleozoic are still hotly debated. Decoupling between zircon Hf and whole-rock Nd isotopic systems for granites results in different interpretations for the above issues. In order to solve the problem, whole-rock Nd–Hf isotopic analyses were conducted on representative early to middle Paleozoic I-type granite and strongly peraluminous granites and rhyolites from the Chinese Altai. The I-type granites show metaluminous to weakly peraluminous feature and have eNd(t) values ranging from − 2.2 to + 0.8 and eHf(t) from + 3.9 to + 12.9, respectively. The strongly peraluminous granites and rhyol…
An experimental study of the role of partial melts of sediments versus mantle melts in the sources of potassic magmatism
2019
Abstract Potassium-rich lavas with K/Na of >2 are common in orogenic and anorogenic intraplate magmatic provinces. However, in the primitive mantle, the concentration of Na exceeds that of K by 10 times. The source of K-rich lavas thus needs to be either K-enriched or Na-depleted to account for high K/Na ratios. The geochemical and isotopic compositions of high 87Sr/86Sr post-collisional lavas show that their mantle source contains a recycled crustal component. These highly K-enriched lavas with crustal like trace element patterns are termed “orogenic lamproites” and are compositionally distinct from K-rich “anorogenic lamproites” that show lower 87Sr/86Sr and a trace element pattern that r…
Drivers of shell growth of the bivalve, Callista chione (L. 1758) - Combined it environmental and biological factors
2018
WOS:000426027100014; Seasonal shell growth patterns were analyzed using the stable oxygen and carbon isotope values of live-collected specimens of the bivalve Callista chione from two sites in the Adriatic Sea (Pag and Cetina, Croatia). Micromilling was performed on the shell surface of three shells per site and shell oxygen isotopes of the powder samples were measured. The timing and rate of seasonal shell growth was determined by aligning the delta O-18(shell)-derived temperatures so that the best fit was achieved with the instrumental temperature curve. According to the data, shells grew only at very low rates or not at all during the winter months, i.e., between January and March. Shell…
Lowering histamine formation in a red Ribera del Duero wine (Spain) by using an indigenous O. oeni strain as a malolactic starter
2016
This study demonstrates for the first time that a non-commercial selected autochthonous O. oeni strain has been used to conduct malolactic fermentation (MLF) while lowering histamine formation in the same winery. Lactic acid bacteria (LAB) were isolated from 13 vats before and after spontaneous MLF at the Pago de Carraovejas winery from the Ribera del Duero region (Spain). Only O. oeni were present, typed and characterized, and both histamine producer and non-producers existed. From the non-producers, one strain was selected to become a starter according to its genetic profile, prevalence in the different wines in the winery, resistance to alcoholic degree, resistance to high polyphenolic c…