Search results for "sort"

γ2-Adaptin, a Ubiquitin-interacting Adaptor, Is a Substrate to Coupled Ubiquitination by the Ubiquitin Ligase Nedd4 and Functions in the Endosomal Pa…

2008

gamma2-Adaptin is a putative member of the clathrin adaptor protein family with unknown physiological function. We previously reported that gamma2-adaptin acts as a ubiquitin receptor by virtue of its ubiquitin-interacting motif. Here we demonstrate that this motif mediates a specific physical interaction with the ubiquitin ligase Nedd4 and promotes ubiquitination of gamma2-adaptin. By mapping regions of Nedd4 involved in binding to gamma2-adaptin, we identified its C2 domain to be essential, whereas the WW and HECT domains are dispensable. Consistent with this, we uncovered that the C2 domain of Nedd4 is ubiquitinated itself and as such is recruited by the ubiquitin-interacting motif of ga…

γ2-Adaptin is functioning in the late endosomal sorting pathway and interacts with ESCRT-I and -III subunits.

2010

Abstractγ2-Adaptin is a clathrin adaptor-related protein with unclear physiological function. Previous studies indicated that γ2-adaptin might act within the multivesicular body (MVB) protein-sorting pathway that is central to receptor down-regulation, lysosome biogenesis, and budding of enveloped viruses. Here, we have analyzed the effects of excess and deficit γ2-adaptin on exogenous and endogenous MVB cargoes and on the MVB machinery itself. Foreign cargoes, like retroviral Gags, are entrapped by overexpressed γ2-adaptin in detergent-insoluble polymers and blocked in budding. When viral budding involves MVB/endosomal structures, excess γ2-adaptin acts by accelerating lysosomal Gag destru…

Angle Factors and Projected Area Factors for Comfort Analysis of Subjects in Complex Confined Enclosures: Analytical Relations and Experimental Resul…

2008

This paper addresses an important problem in the evaluation of the thermal comfort of people living or working in the sort of confined spaces typical of current architecture. In the details, a new algorithm is proposed for the evaluation of the angle factors of people within rooms characterized by complex shapes, where the envelope components are not always mutually orthogonal. The algorithm is based on field data obtained by means of an experimental photographic apparatus which allows measurements of projected area factors of seated or standing people in such complex confined environments.

Historia verdadera, y exemplar del Gran Cisma de Inglaterra, con sus factores Henrico Octavo, y Ana Bolena. Sacada de Don Fray Diego de Yepes ... el …

Data presa de Palau Sign.: [A]-B2, C[8 Reclams Grav. xil. a la port. avant del tít., representant la mort decapitada d'Anna Bolena Frisos

Users’ Preferences for Designing Spaces under Urban Bridges as Vital Urban Spaces

2018

Today’s fast-paced urbanization process has caused many problems in urban development. Therefore, urban space is slowly losing its nature and disappearing due to the speed of rapid urban development. Trying to keep up with the modern era’s prevalent epoch of roads and bridges, urban policies in Iran have focused on developing road networks in recent years. Thus numerous elevated structures, urban highways and bridges are used to connect the urban fabric of the country’s cities, enabling the smooth transition of traffic in its cities. Although many view urban highways merely as tools for mobility; it is true that they influence on urban structure and the communities that they interconnect. H…

Hunting for valuables from landfills and assessing their market opportunities A case study with Kudjape landfill in Estonia

2017

Landfill mining is an alternative technology that merges the ideas of material recycling and sustainable waste management. This paper reports a case study to estimate the value of landfilled materials and their respective market opportunities, based on a full-scale landfill mining project in Estonia. During the project, a dump site (Kudjape, Estonia) was excavated with the main objectives of extracting soil-like final cover material with the function of methane degradation. In total, about 57,777 m3 of waste was processed, particularly the uppermost 10-year layer of waste. Manual sorting was performed in four test pits to determine the detailed composition of wastes. 11,610 kg of waste was…

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

2019

P.B. participated in the design, carried out the study, implemented the websites and search systems and wrote the manuscript. RELISH consortium annotated the articles. Y.Z. conceived the study, participated in the initial design, assisted in analyzing data and wrote the manuscript. All authors read, contributed to the discussion and approved the manuscript. Rayner Gonzálezlez-Prendes is member of the RELISH consortium. Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly deve…

Funebres oraciones, que en las exequias pomposas, que hizieron a ... Doña María Luysa de Borbon Muger de ... Carlos Segundo ... la Vills de Alzira, y…

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Portada orlada Postil·les marginals Signatures: A-G4, H3

Automatic image-based identification and biomass estimation of invertebrates

2020

1. Understanding how biological communities respond to environmental changes is a key challenge in ecology and ecosystem management. The apparent decline of insect populations necessitates more biomonitoring but the time-consuming sorting and expert-based identification of taxa pose strong limitations on how many insect samples can be processed. In turn, this affects the scale of efforts to map and monitor invertebrate diversity altogether. Given recent advances in computer vision, we propose to enhance the standard human expert-based identification approach involving manual sorting and identification with an automatic image-based technology. 2. We describe a robot-enabled image-based ident…

Inducing the Lyndon Array

2019

In this paper we propose a variant of the induced suffix sorting algorithm by Nong (TOIS, 2013) that computes simultaneously the Lyndon array and the suffix array of a text in $O(n)$ time using $\sigma + O(1)$ words of working space, where $n$ is the length of the text and $\sigma$ is the alphabet size. Our result improves the previous best space requirement for linear time computation of the Lyndon array. In fact, all the known linear algorithms for Lyndon array computation use suffix sorting as a preprocessing step and use $O(n)$ words of working space in addition to the Lyndon array and suffix array. Experimental results with real and synthetic datasets show that our algorithm is not onl…