Search results for "spain"

showing 10 items of 2556 documents

Yogurt consumption and abdominal obesity reversion in the PREDIMED study.

2016

Yogurt consumption and abdominal obesity reversion in the PREDIMED study. BACKGROUND AND AIMS: Evidence on the association yogurt consumption and obesity is not conclusive. The aim of this study was to prospectively evaluate the association between yogurt consumption, reversion of abdominal obesity status and waist circumference change in elderly. METHODS AND RESULTS: 4545 individuals at high cardiovascular risk were prospectively followed. Total, whole-fat and low-fat yogurt consumption were assessed using food frequency questionnaires. Generalized estimating equations were used to analyze the association between yogurt consumption and waist circumference change (measured at baseline and y…

0301 basic medicineMaleTime FactorsEndocrinology Diabetes and MetabolismMedicine (miscellaneous)0939-4753Logistic regressionDiet MediterraneanDieta mediterràniaRisk FactorsOdds RatioFood scienceProspective StudiesGeneralized estimating equationAbdominal obesityAged 80 and overBioquímica y tecnologíaNutrition and DieteticsAge Factorsfood and beveragesMiddle AgedCircumferenceYogurtDiet RecordsBiochemistry and technologyTreatment OutcomeCardiovascular DiseasesObesity AbdominalOlder adultsObesitatFemalemedicine.symptomWaist CircumferenceCardiology and Cardiovascular Medicinemedicine.medical_specialtyWaistIogurtBioquímica i biotecnologiaabdominal obesity03 medical and health sciencesInternal medicineWeight LossmedicineHumansAgedConsumption (economics)030109 nutrition & dieteticsbusiness.industryPREDIMED studyOdds ratiomedicine.diseaseObesityDietary FatsLogistic ModelsSpainMultivariate AnalysisLinear Modelsbusiness
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Tomato sauce enriched with olive oil exerts greater effects on cardiovascular disease risk factors than raw tomato and tomato sauce: a randomized tri…

2016

Epidemiological studies have observed a negative association between tomato intake and the incidence of cardiovascular disease. As tomato sauces are usually cooked with the addition of oil, some studies have pointed out that both processes may increase the bioavailability of the bioactive compounds. However, the effect of consumption of raw tomatoes and tomato sauces on inflammation biomarkers and adhesion molecules related to atherosclerosis remains unknown. The aim of this study was to test the postprandial effects of a single dose of raw tomatoes (RT), tomato sauce (TS) and tomato sauce with refined olive oil (TSOO) on cardiovascular disease risk factors. We performed an open, prospectiv…

0301 basic medicineMaleTime FactorsLymphocyteCD36postprandial030204 cardiovascular system & hematologytomatochemistry.chemical_compound0302 clinical medicineSolanum lycopersicumRisk FactorsTomàquetsFood scienceCookingProspective StudiesProspective cohort studyNutrition and DieteticsCross-Over Studiesbiologycardiovascularcookedfood and beveragesPostprandial PeriodLipidsInflamaciótomato; postprandial; cardiovascular; cooked; food matrix; bioavailabilityOli d'olivaPostprandialmedicine.anatomical_structureCardiovascular diseasesEstudi de casosCardiovascular DiseasesFemaleInflammation Mediatorslcsh:Nutrition. Foods and food supplyNutritive ValueAdultAdolescentlcsh:TX341-641Article03 medical and health sciencesYoung AdultTomatoesmedicineHumansSugarOlive OilInflammation030109 nutrition & dieteticsCholesterolbusiness.industryMalalties cardiovascularsProtective FactorsCrossover studyBioavailabilityDietchemistrySpainFruitbiology.proteinCase studiesbusinessEnergy IntakebioavailabilityCell Adhesion MoleculesBiomarkersfood matrixOlive oilFood Science
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Dietary Marine ω-3 Fatty Acids and Incident Sight-Threatening Retinopathy in Middle-Aged and Older Individuals With Type 2 Diabetes Prospective Inves…

2016

IMPORTANCE: Diabetic retinopathy (DR) is a devastating complication of individuals with type 2 diabetes mellitus. The retina is rich in long-chain ω−3 polyunsaturated fatty acids (LCω3PUFAs), which are substrate for oxylipins with anti-inflammatory and antiangiogenic properties. Experimental models support dietary LCω3PUFA protection against DR, but clinical data are lacking. OBJECTIVE: To determine whether LCω3PUFA intake relates to a decreased incidence of sight-threatening DR in individuals with type 2 diabetes older than 55 years. DESIGN, SETTING, AND PARTICIPANTS: In late 2015, we conceived a prospective study within the randomized clinical trial Prevención con Dieta Mediterránea (PRED…

0301 basic medicineMaleTime FactorsMediterranean diet2168-6165Type 2 diabetesDieta mediterrànialaw.inventionRandomized controlled triallawRisk FactorsProspective StudiesProspective cohort studyAged 80 and overBioquímica y tecnologíaDiabetisIncidenceDiabetic retinopathyMiddle AgedType 2 DiabetesBiochemistry and technologyTreatment OutcomeFemalemedicine.medical_specialtyBioquímica i biotecnologiaRisk AssessmentOlder IndividualsArticle03 medical and health sciencesInternal medicineDiabetes mellitusFatty Acids Omega-3medicineHumansAgedDiabetic Retinopathybusiness.industryType 2 Diabetes MellitusPREDIMED studymedicine.diseaseSurgeryOphthalmology030104 developmental biologyDiabetes Mellitus Type 2SeafoodSpainRelative riskDietary SupplementsRetinopatia diabèticabusinessFollow-Up Studies
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Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.

2017

Background-The relationship between plasma concentrations of betaine and choline metabolism and major cardiovascular disease (CVD) end points remains unclear. We have evaluated the association between metabolites from the choline pathway and risk of incident CVD and the potential modifying effect of Mediterranean diet interventions. Methods and Results-We designed a case-cohort study nested within the PREDIMED (Prevention With Mediterranean Diet) trial, including 229 incident CVD cases and 751 randomly selected participants at baseline, followed up for 4.8 years. We used liquid chromatography-tandem mass spectrometry to measure, at baseline and at 1 year of follow-up, plasma concentrations …

0301 basic medicineMaleTime FactorsMediterranean dietEpidemiologymodelos de riesgos proporcionaleshumanosSistema cardiovascular -- Malaltieséteres de fosfolípidosDisease030204 cardiovascular system & hematologyGut floraDiet MediterraneanCholinechemistry.chemical_compound0302 clinical medicineBetainecardiovascular diseaseRisk FactorsTandem Mass Spectrometryestudios prospectivosmetabolómicaCholineProspective StudiesTrimethylamine-n-oxidemediana edadOriginal ResearchDiet and Nutritionmetilaminas2. Zero hungerAged 80 and overChromatographyancianoCholine metabolismbiologydietaresultado del tratamientoIncidencePhospholipid Ethersdistribución de la ji al cuadradoMiddle AgedCardiovascular disease3. Good healthPrimary PreventioncolinaTreatment OutcomeCardiovascular Diseasesespectrometría de masas en tándemPlasma concentrationProfileFemaleCardiology and Cardiovascular Medicinefosforilcolinamedicine.medical_specialtyPhosphorylcholineestudios de casos y controlesenfermedades cardiovascularesGut microbiotaincidencia03 medical and health sciencesMethylaminesfactores de tiempoInternal medicineMediterranean dietOxidationmedicinefactores de riesgoHumansMetabolomicsanálisis multifactorialDieta -- Mediterrània Regió de lacromatografíaAgedProportional Hazards ModelsChi-Square Distributiongut microbiotabusiness.industrybetaínaPlasma sanguiniLifestylebiology.organism_classificationPredimedDietBetainePhosphatidylcholine030104 developmental biologyEndocrinologychemistrySpainCase-Control StudiesMultivariate AnalysisbusinessBiomarkersChromatography Liquid
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Concentrations of urinary arsenic species in relation to rice and seafood consumption among children living in Spain.

2017

Inorganic arsenic (i-As) has been related to wide-ranging health effects in children, leading to lifelong concerns. Proportionally, dietary i-As exposure dominates in regions with low arsenic drinking water. This study aims to investigate the relation between rice and seafood consumption and urinary arsenic species during childhood and to assess the proportion of urinary i-As metabolites. Urinary arsenic species concentration in 400 4-year-old children living in four geographical areas of Spain, in addition to repeated measures from 100 children at 7 years of age are included in this study. Rice and seafood products intake was collected from children's parents using a validated food frequen…

0301 basic medicineMaleUrinary systemPopulationchemistry.chemical_elementFood ContaminationUrine010501 environmental sciencesBiology01 natural sciencesBiochemistryArticleArsenic03 medical and health scienceschemistry.chemical_compoundEnvironmental healthSurveys and QuestionnairesJournal ArticleHumansFood scienceeducationChildArsenic0105 earth and related environmental sciencesGeneral Environmental ScienceConsumption (economics)education.field_of_studyintegumentary systemfood and beveragesOryzaEnvironmental exposureEnvironmental ExposureDiet030104 developmental biologychemistrySeafoodSpainChild PreschoolEnvironmental PollutantsFemaleArsenobetaineFood contaminantEnvironmental MonitoringEnvironmental research
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Blood zinc levels and cognitive and functional evaluation in non-demented older patients.

2018

A complete battery of geriatric and psychometric tests was used to determine whether plasma-borne zinc (Zn), a key ion in neuroplasticity, can be associated with the severity of functional, psychological and cognitive impairment in non-demented older individuals. There was a significant positive correlation between plasma Zn levels and the concentration subcategory measured with the Mini-Mental State Examination (MMSE) test (p  0.001), but not the total MMSE score, and the levels were significantly reduced in polymedicated patients (defined as concurrent administration of5 drugs). No correlations were found between plasma Zn levels and depressive symptoms measured with the Yesavage scale fo…

0301 basic medicineMalemedicine.medical_specialtyAgingActivities of daily livingBarthel indexBiochemistrySeverity of Illness Index03 medical and health sciences0302 clinical medicineEndocrinologyCognitionOlder patientsInternal medicineActivities of Daily LivingGeneticsMedicineHumansCognitive DysfunctionMolecular BiologyGeriatric AssessmentDepression (differential diagnoses)AgedAged 80 and overPsychiatric Status Rating ScalesFunctional evaluationMini–Mental State Examinationmedicine.diagnostic_testbusiness.industryDepressionCognitionCell BiologyMiddle AgedPoor sleepZinc030104 developmental biologySpainFemalebusiness030217 neurology & neurosurgeryExperimental gerontology
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Endocrinology of Aging From a Muscle Function Point of View: Results From the Toledo Study for Healthy Aging.

2016

Aging is a process that involves a reduction in muscle strength and anabolic hormone concentrations, which impacts significantly on health.To study the hormone/total strength (H/TS) ratio as a proxy of anabolic insensitivity status in elders, and its relationship with disability, hospitalization, and mortality risk.A total of 1462 persons aged ≥65 years from the Toledo Study of Healthy Aging participated in this study. Serum concentrations of insulin like growth factor 1, total and free testosterone, dehydroepiandrosterone, dehydroepiandrosterone sulfate, and 17β-estradiol were measured. Total maximal voluntary isometric strength was obtained (handgrip, shoulder, hip, and knee) using standa…

0301 basic medicineMalemedicine.medical_specialtyAnabolismmedicine.medical_treatmentDehydroepiandrosteroneEndocrine SystemIsometric exercisePhysical strengthLogistic regressionHealthy Aging03 medical and health scienceschemistry.chemical_compoundInsulin-like growth factor0302 clinical medicineDehydroepiandrosterone sulfateInternal medicinemedicineHumans030212 general & internal medicineMuscle StrengthMuscle SkeletalGeneral NursingAgedbusiness.industryHealth PolicyMortality rateGeneral MedicineHospitalization030104 developmental biologyEndocrinologychemistrySpainFemaleGeriatrics and GerontologybusinessJournal of the American Medical Directors Association
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Community-acquired febrile urinary tract infection caused by extended-spectrum beta-lactamase-producing bacteria in hospitalised infants.

2015

Abstract Introduction Extended-spectrum beta-lactamase (ESBL) producing bacteria are infrequent pathogens of urinary tract infections in children. The objective of our study was to investigate the presence, clinically associated characteristics and risk factors for acquisition of urinary tract infection/acute pyelonephritis (UTI/APN) in hospitalised children Methods A case-control study in a second level community hospital in Spain, in which 537 episodes of UTI/APN were investigated in a retrospective study between November 2005 and August 2014. Cases were patients with ESBL strains. For each case, four ESBL-negative controls were selected. A questionnaire with the variables of interest was…

0301 basic medicineMalemedicine.medical_specialtyFevermedicine.drug_classmedicine.medical_treatment030106 microbiologyAntibioticsHospitals CommunityComorbidityFosfomycinTazobactamVesicoureteral refluxMeropenembeta-Lactam Resistancebeta-Lactamases03 medical and health sciencesBacterial ProteinsRisk FactorsInternal medicineSurveys and Questionnairespolycyclic compoundsmedicineEscherichia coliHumansEscherichia coli InfectionsRetrospective StudiesVesico-Ureteral RefluxInpatientsPyelonephritisbusiness.industryInfantbiochemical phenomena metabolism and nutritionbacterial infections and mycosesmedicine.diseaseSurgeryCommunity-Acquired InfectionsSpainCase-Control StudiesUrinary Tract InfectionsBeta-lactamasebacteriaGentamicinFemalebusinessmedicine.drugPiperacillinEnfermedades infecciosas y microbiologia clinica
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Preferred Music Listening Intervention in Nursing Home Residents with Cognitive Impairment: A Randomized Intervention Study.

2019

Background The current trend in addressing symptoms of dementia comprises non-pharmacological strategies such as music interventions for the management and improvement of cognitive function, memory, agitation, depression, or anxiety. Objective To determine the impact of a preferred music listening group intervention upon the functional, cognitive, and emotional dimensions in nursing home residents. Methods A randomized intervention study was carried out. The study was conducted from June to August 2015, and involved a preferred music listening group intervention lasting 60 minutes, 5 days/week during 8 weeks. A total of 119 adults aged ≥65 years, with annual permanent residence in the nursi…

0301 basic medicineMalemedicine.medical_specialtyPsychological intervention03 medical and health sciences0302 clinical medicineIntervention (counseling)medicineDementiaHomes for the AgedHumansCognitive DysfunctionMusic TherapyDepression (differential diagnoses)AgedAged 80 and overbusiness.industryGeneral NeuroscienceTinetti testCognitionPatient PreferenceGeneral Medicinemedicine.diseasehumanitiesNursing HomesPsychiatry and Mental healthClinical Psychology030104 developmental biologySpainPhysical therapyAuditory PerceptionAnxietyResidenceFemaleGeriatrics and Gerontologymedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesJournal of Alzheimer's disease : JAD
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Clinical effectiveness of influenza vaccination after allogeneic hematopoietic stem cell transplantation: A cross-sectional prospective observational…

2018

Abstract Background Vaccination is the primary method for preventing influenza respiratory virus infection (RVI). Although the influenza vaccine is able to achieve serological responses in some allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients, its clinical benefits are still uncertain. Methods In this prospective, cross-sectional study, we retrospectively analyzed the effect of inactivated trivalent influenza vaccination on the prevalence of influenza RVI in a consecutive cohort of 136 allo-HSCT adult recipients who developed 161 RVI over 5 flu seasons (from 2013 to 2018). Respiratory viruses in upper– and/or lower–respiratory tract specimens were tested using multi…

0301 basic medicineMalemedicine.medical_treatmentHematopoietic stem cell transplantationinfluenza virus0302 clinical medicineRisk FactorsOdds RatioMedicine030212 general & internal medicineProspective StudiesArticles and CommentariesImmunodeficiencybiologyVaccinationHematopoietic Stem Cell Transplantationvirus diseasesMiddle AgedVaccinationHospitalizationInfectious DiseasesTreatment OutcomeInfluenza VaccinesCohortFemaleMicrobiology (medical)Adultmedicine.medical_specialtyAdolescentInfluenza vaccine030106 microbiologyOrthomyxoviridae03 medical and health sciencesImmunocompromised HostYoung AdultInternal medicineInfluenza HumanHumansTransplantation Homologousallogeneic hematopoietic stem cell transplantationRisk factorAgedRetrospective Studiescommunity-acquired respiratory virusbusiness.industryOdds ratiomedicine.diseasebiology.organism_classificationCross-Sectional StudiesSpainbusinessimmunodeficiency score index
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