Search results for "spain"

showing 10 items of 2556 documents

Effectiveness and safety of ombitasvir, paritaprevir, ritonavir ± dasabuvir ± ribavirin: An early access programme for Spanish patients with genotype…

2017

Over the last 5 years, therapies for hepatitis C virus (HCV) infection have improved significantly, achieving sustained virologic response (SVR) rates of up to 100% in clinical trials in patients with HCV genotype 1. We investigated the effectiveness and safety of ombitasvir/paritaprevir/ritonavir +/- dasabuvir in an early access programme. This was a retrospective, multicentre, national study that included 291 treatment-naive and treatment-experienced patients with genotype 1 or 4 HCV infection. Most patients (65.3%) were male, and the mean age was 57.5years. The mean baseline viral load was 6.1 log, 69.8% had HCV 1b genotype, 72.9% had cirrhosis and 34.7% were treatment-naive. SVR at 12 w…

MaleCirrhosisSustained Virologic ResponseHepacivirusmedicine.disease_causechemistry.chemical_compound0302 clinical medicinesevere fibrosisdasabuvirMedicineAged 80 and overMiddle AgedInfectious DiseasesTreatment Outcome030220 oncology & carcinogenesis030211 gastroenterology & hepatologyDrug Therapy CombinationFemaleViral loadmedicine.drugAdultmedicine.medical_specialtyDrug-Related Side Effects and Adverse ReactionsGenotypeHepatitis C viruscompassionate useAntiviral Agents03 medical and health sciencesVirologyInternal medicineHumansAdverse effectAgedRetrospective StudiesHepatologybusiness.industryRibavirinparitaprevirHepatitis C Chronicmedicine.diseaseVirologydigestive system diseasesOmbitasvirDiscontinuationombitasvirchemistryParitaprevirSpainhepatitis Cbusiness
researchProduct

Surrounding Greenness and Pregnancy Outcomes in Four Spanish Birth Cohorts

2012

Background: Green spaces have been associated with improved physical and mental health; however, the available evidence on the impact of green spaces on pregnancy is scarce. Objectives: We investigated the association between surrounding greenness and birth weight, head circumference, and gestational age at delivery. Methods: This study was based on 2, 393 singleton live births from four Spanish birth cohorts (Asturias, Gipuzkoa, Sabadell, and Valencia) located in two regions of the Iberian Peninsula with distinct climates and vegetation patterns (2003–2008). We defined surrounding greenness as average of satellite-based Normalized Difference Vegetation Index (NDVI) (Landsat 4–5 TM data at …

MaleClimateHealth Toxicology and MutagenesisEmbaràs010501 environmental sciencesHead circumference01 natural sciencesCohort Studies0302 clinical medicinePregnancyProspective Studies030212 general & internal medicine2. Zero hungerPregnancy OutcomeCohortGestational ageInfants -- Alimentació3. Good healthCohort effectCohortReproductive healthTerm BirthFemaleSeasonsEndocrinologia obstètricaAdultCephalometryNDVIBirth weightEnvironmentBiologyNormalized Difference Vegetation Index03 medical and health sciencesBirth weightmedicineHumans0105 earth and related environmental sciencesGreen spacePregnancyPregnancy outcomesResearchPublic Health Environmental and Occupational HealthInfantGestational agemedicine.diseaseConfidence intervalSocioeconomic FactorsSpainGreennessINMADemography
researchProduct

The relationship of task self-efficacy and role efficacy beliefs to role performance in Spanish youth soccer

2004

The aim of this study was to examine the relationship between role efficacy and role performance after controlling for the effects of task self-efficacy. Two hundred and ninety-five Spanish youth soccer players from 20 teams completed self-report measures of task self-efficacy, role efficacy and role performance at the mid-point of a competitive season. The 20 team coaches also provided ratings of each of their players' role performances at mid-season. Consistent with hypotheses, bivariate correlations showed task self-efficacy and role efficacy were positively related to role performance ratings. Hierarchical regression analyses revealed that role efficacy contributed significantly to the …

MaleCompetitive BehaviorAdolescentTeam sportPhysical Therapy Sports Therapy and RehabilitationBivariate analysisFootballDevelopmental psychologyTask (project management)SoccerTask Performance and AnalysisHumansOrthopedics and Sports MedicineSelf-efficacybiologyAthletesMultilevel modelRegression analysisAchievementbiology.organism_classificationSelf EfficacySpainRegression AnalysisPsychologyGoalsSocial psychologyJournal of Sports Sciences
researchProduct

Solving Man-Induced Large-Scale Conservation Problems: The Spanish Imperial Eagle and Power Lines

2011

[Background] Man-induced mortality of birds caused by electrocution with poorly-designed pylons and power lines has been reported to be an important mortality factor that could become a major cause of population decline of one of the world rarest raptors, the Spanish imperial eagle (Aquila adalberti). Consequently it has resulted in an increasing awareness of this problem amongst land managers and the public at large, as well as increased research into the distribution of electrocution events and likely mitigation measures.

MaleConservation of Natural ResourcesEnvironmental EngineeringEcological MetricsPopulation SizeEagleslcsh:MedicineLibrary scienceSpanish imperial eagleEcological RiskElectric Power SuppliesEngineeringOrnithologyAnimalsHumansConservation sciencelcsh:ScienceBiologyConservation ScienceMultidisciplinaryGeographyEcologyPopulation Biologybiologylcsh:RBiodiversitybiology.organism_classificationElectric InjuriesGeographyCommunity EcologySpainFemalelcsh:QChristian ministryPopulation EcologyZoologyEnvironmental ProtectionResearch Article
researchProduct

Health Assets, Vocation and Zest for Healthcare Work. A Salutogenic Approach to Active Coping among Certified Nursing Assistant Students

2020

People&rsquo

MaleCoping (psychology)Health Toxicology and MutagenesisPopulationnurselcsh:MedicineInterpersonal communicationArticleactive coping*certified nurse assistantcertified nurse assistant03 medical and health sciences0302 clinical medicineNursingNursing AssistantsAdaptation PsychologicalHealth careHumans030212 general & internal medicineOccupationsStudentsasset-based approachNursing Assistanteducation*active copingeducation.field_of_study030505 public healthZestbusiness.industry*health assets model*vocationlcsh:Rhealth assets modelPublic Health Environmental and Occupational Healthsalutogenic model of health*salutogenic model of healthHealth promotionSpainVocational educationvocationFemale*asset-based approach*nurse0305 other medical sciencePsychologybusinessStress PsychologicalInternational Journal of Environmental Research and Public Health
researchProduct

A Cross-Country Examination on the Fear of COVID-19 and the Sense of Loneliness during the First Wave of COVID-19 Outbreak

2021

The aim of the current study is to examine gender, age. and cross-country differences in fear of COVID-19 and sense of loneliness during the lockdown, by comparing people from those countries with a high rate of infections and deaths (e.g., Spain and Italy) and from countries with a mild spread of infection (e.g., Croatia, Serbia, Slovakia, Slovenia, and Bosnia and Herzegovina). A total of 3876 participants (63% female) completed an online survey on “Everyday life practices in COVID-19 time” in April 2020, including measures of fear of COVID-19 and loneliness. Males and females of all age groups in countries suffering from the powerful impact of the COVID-19 pandemic reported greater fear o…

MaleCross-country Fear of COVID-19 Loneliness Psychosocial distress COVID-19Health Toxicology and MutagenesisSloveniapandemijecoronaviruslcsh:MedicineDisease Outbreaksrestrictions0302 clinical medicineEconomic costPandemicstrah030212 general & internal medicineEveryday lifeukrepipublic healthLonelinessFearItalypsihosocialne stiskefearFemalemedicine.symptomPsychologySerbiaisolationmedicine.medical_specialtySlovakiaCoronavirus disease 2019 (COVID-19)Croatiafear of COVID-19Article03 medical and health sciencesmedicinelonelinessHumansPandemicsAgedBosnia and Herzegovinaudc:616-036.21:614:616.89-008.441osamljenostSARS-CoV-2koronavirusPublic healthpandemicjavno zdravjelcsh:RPublic Health Environmental and Occupational HealthOutbreakCOVID-19psychosocial distressMental healthSpainCommunicable Disease Controlcross-country030217 neurology & neurosurgeryDemographyizolacijaInternational Journal of Environmental Research and Public Health
researchProduct

PPAR-alpha L162V and PGC-1 G482S gene polymorphisms, but not PPAR-gamma P12A, are associated with alcohol consumption in a Spanish Mediterranean popu…

2008

Abstract Background Peroxisome Proliferator-Activated Receptors (PPARs) and its co-activators are regulatory elements of the cellular lipid homeostasis and have been associated with feeding behavior modulation. Animal models suggest that these genes may be involved in alcohol consumption regulation. However, no studies in humans exist. Our aim is to estimate the possible association between polymorphisms in the PPAR-α , PPAR-γ and PPAR-γ co-activator 1A ( PGC-1A ) genes and alcohol consumption in humans. Methods We have conducted a cross-sectional study between the PPAR-α L162V, PPAR-γ P12A and PGC-1A G482S polymorphisms, and alcohol consumption in a general Mediterranean Spanish population…

MaleCross-sectional studyClinical BiochemistryPeroxisome Proliferator-Activated ReceptorsPeroxisome proliferator-activated receptorAlcoholBiochemistryGenechemistry.chemical_compoundGene FrequencyPolymorphism (computer science)Heat-Shock ProteinsGeneticschemistry.chemical_classificationAged 80 and overeducation.field_of_studyMediterranean RegionGeneral MedicineMiddle AgedPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaFemaleAdultmedicine.medical_specialtyAdolescentAlcohol DrinkingGenotypePopulationSingle-nucleotide polymorphismBiologyPolymorphism Single NucleotideYoung AdultInternal medicinemedicineHumansPPAR alphaeducationAllele frequencyAllelesAgedEthanolPolymorphism GeneticEthanolBiochemistry (medical)DNASingle nucleotide polymorphismEndocrinologyCross-Sectional StudieschemistrySocioeconomic FactorsSpainAlcoholic beveragesTranscription FactorsClinica chimica acta; international journal of clinical chemistry
researchProduct

People would rather see a physician than a dentist when experiencing a long-standing oral ulceration. A population-based study in Spain

2020

Background Primary care physicians have been reported to be the first choice for patients with oral ulcerations. This study investigates the health-seeking behaviour of lay public in Galicia (North-western Spain) if experiencing a long-standing oral ulceration. Material and Methods Cross-sectional population-based survey of randomly selected respondents conducted from March 1, 2015 to 30 June 2016. Results A total of 5,727 pedestrians entered the study (response rate: 53%), mostly in the 45-64 age group (30.2%; n=1,728), 47.7% of them (n=2,729) were males. Most participants (42.1%; n=2,411) reported to visit their dentist once a year and had secondary or compulsory education as their highes…

MaleCross-sectional studyDentistsPopulationMEDLINEDentistryPrimary careHumansMedicineeducationGeneral DentistryAgedResponse rate (survey)education.field_of_studyOral Medicine and Pathologybusiness.industryResearchPrimary care physicianOral ulcerations:CIENCIAS MÉDICAS [UNESCO]Population based studyCross-Sectional StudiesOtorhinolaryngologySpainUNESCO::CIENCIAS MÉDICASSurgerybusiness
researchProduct

Screen media usage, sleep time and academic performance in adolescents: clustering a self-organizing maps analysis.

2014

Screen media usage, sleep time and socio-demographic features are related to adolescents' academic performance, but interrelations are little explored. This paper describes these interrelations and behavioral profiles clustered in low and high academic performance. A nationally representative sample of 3,095 Spanish adolescents, aged 12 to 18, was surveyed on 15 variables linked to the purpose of the study. A Self-Organizing Maps analysis established non-linear interrelationships among these variables and identified behavior patterns in subsequent cluster analyses. Topological interrelationships established from the 15 emerging maps indicated that boys used more passive videogames and compu…

MaleCross-sectional studyEpidemiologyEconomicsIntelligenceEconomics of Training and EducationCulturePsychological interventionSocial Scienceslcsh:MedicineAcademic achievementPediatricsDevelopmental psychologyCultural AnthropologyChild DevelopmentSociologySurveys and QuestionnairesHuman PerformanceMedicine and Health SciencesCluster AnalysisPsychologyPublic and Occupational HealthChildlcsh:ScienceHuman CapitalMultidisciplinarySocial ResearchSocioeconomic Aspects of HealthEducational StatusFemalePsychologyBehavioral and Social Aspects of HealthResearch ArticleSelf-organizing mapAdolescentAffect (psychology)Adolescent MedicineMental Health and PsychiatryHumansCluster analysisSocioeconomic statusSedentary lifestyleBehaviorComputerslcsh:RCognitive PsychologyBiology and Life SciencesAchievementSocial EpidemiologyHealth CareCross-Sectional StudiesVideo GamesSpainAnthropologyDevelopmental PsychologyHuman IntelligenceCognitive Sciencelcsh:QSedentary BehaviorSleepCell PhoneNeurosciencePLoS ONE
researchProduct

Smartphone Addiction Inventory (SPAI): Translation, adaptation and validation of the tool in Spanish adult population

2018

The wide functionality and the vast range of attributes offered by smartphones has led to a substantial increase in the average amount of time these devices are used per day. An excessive use of these tools has been shown to result in symptomatology similar to psychological disorders caused by substance addiction. In Spain, smartphone use has risen exponentially but the effects of this increase remain unclear. Therefore, an instrument is required to help determine the extent of smartphone addiction in the Spanish population. The Smartphone Addiction Inventory (SPAI) is a valid and reliable mean to identify and measure smartphone addiction and so, the aim of this research is the translation …

MaleCultureSocial Scienceslcsh:Medicine050109 social psychologyGeographical locationsMathematical and Statistical Techniques0302 clinical medicineSociologyGoodness of fitSurveys and QuestionnairesMedicine and Health SciencesPsychologyPublic and Occupational Healthlcsh:ScienceReliability (statistics)media_commonMultidisciplinaryStatistics05 social sciencesDependència (Psicologia)Middle AgedConfirmatory factor analysisEuropePhysical SciencesEngineering and TechnologyFemaleSmartphonemedicine.symptomPsychologyFactor AnalysisResearch ArticleClinical psychologyAdultBehavioral addictionAdolescentPsychometricsSubstance-Related Disordersmedia_common.quotation_subjectEquipmentAddictionResearch and Analysis MethodsYoung Adult03 medical and health sciencesCronbach's alphaCross-Cultural StudiesMental Health and PsychiatrymedicineHumans0501 psychology and cognitive sciencesEuropean UnionStatistical MethodsAdaptation (computer science)Communication EquipmentAddictionSubstance Addictionlcsh:RBiology and Life SciencesModels TheoreticalAbstinence030227 psychiatryBehavior AddictiveSpainBehavioral AddictionAge GroupsTelèfon mòbilPeople and PlacesPopulation Groupingslcsh:QSelf ReportCell PhonesMathematics
researchProduct