Search results for "spectrum"
showing 10 items of 2043 documents
International Society for Extracellular Vesicles: first annual meeting, April 17-21, 2012: ISEV-2012
2012
Extracellular micro- and nano-scale membrane vesicles produced by different cells are recognized as an essential entity of physiological fluids in a variety of organisms and function as mediators of intercellular communication employed for the regulation of multiple systemic and local processes. In the last decade, an exponential amount of experimental work was dedicated to exploring the biogenesis and secretion mechanisms, physiological and pathological functions and potential applications of the extracellular vesicles (EVs). Noteworthy is the large heterogeneity of in vitro and in vivo models applied, technical approaches developed in these studies and the diversity of designations assign…
Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder
2020
Celiac Disease (CD) is an immune-mediated disease triggered by the ingestion of wheat gliadin and related prolamins from other cereals, such as barley and rye. Immunity against these cereal-derived proteins is mediated by pro-inflammatory cytokines produced by both innate and adaptive system response in individuals unable to adequately digest them. Peptides generated in this condition are absorbed across the gut barrier, which in these patients is characterized by the deregulation of its permeability. Here, we discuss a possible correlation between CD and Autistic Spectrum Disorder (ASD) pathogenesis. ASD can be induced by an excessive and inappropriate brain opioid activity during the neon…
Improved measurement of $^8$B solar neutrinos with $1.5 kt·y$ of Borexino exposure
2017
We report on an improved measurement of the $^8$B solar neutrino interaction rate with the Borexino experiment at the Laboratori Nazionali del Gran Sasso. Neutrinos are detected via their elastic scattering on electrons in a large volume of liquid scintillator. The measured rate of scattered electrons above 3 MeV of energy is $0.223\substack{+0.015 \\ -0.016}\,(stat)\,\substack{+0.006 \\ -0.006}\,(syst)$ cpd/100 t, which corresponds to an observed solar neutrino flux assuming no neutrino flavor conversion of $\Phi\substack{\rm ES \\ ^8\rm B}=2.57\substack{+0.17 \\ -0.18}(stat)\substack{+0.07\\ -0.07}(syst)\times$10$^6$ cm$^{-2}\,$s$^{-1}$. This measurement exploits the active volume of the …
Multi-resolution anisotropy studies of ultrahigh-energy cosmic rays detected at the Pierre Auger Observatory
2017
We report a multi-resolution search for anisotropies in the arrival directions of cosmic rays detected at the Pierre Auger Observatory with local zenith angles up to $80^\circ$ and energies in excess of 4 EeV ($4 \times 10^{18}$ eV). This search is conducted by measuring the angular power spectrum and performing a needlet wavelet analysis in two independent energy ranges. Both analyses are complementary since the angular power spectrum achieves a better performance in identifying large-scale patterns while the needlet wavelet analysis, considering the parameters used in this work, presents a higher efficiency in detecting smaller-scale anisotropies, potentially providing directional informa…
Influencia del sesgo de género en el diagnóstico de trastorno de espectro autista: una revisión
2018
espanolLa prevalencia del trastorno de espectro autista (TEA) se ha incrementado en los ultimos anos, en parte debido a las mejoras de los metodos de deteccion y en parte a las modi- ficaciones en la definicion que se han ido incorporando a los manuales diagnosticos. Este incremento ha provocado que el indice de prevalencia por genero sea en la actualidad de un 1,4/1, segun algunos autores, o hasta de un 15,7/1 segun otros, con un numero muy superior de varones que reciben el diagnostico en comparacion con el numero de mujeres que lo reciben. Las distintas explicaciones que se han dado a esta cuestion apuntan a unas determinadas diferencias de genero en las manifestaciones sintomaticas del …
Stippled epiphyses in fetal alcohol syndrome.
1990
We report on punctate epiphyseal calcifications (stippled epiphyses) in the fetal alcohol syndrome and present the differential diagnosis of chondrodysplasia punctata. A literature survey shows that epiphyseal calcifications accompanying alcoholic embryopathy are regularly located in the lower limbs and rarely found in the upper extremities.
Poznawczo-behawioralne programy terapeutyczne wykorzystywane w pracy z wymagającymi wsparcia adolescentami z zaburzeniami ze spektrum autyzmu (ASD L1…
2020
Artykuł zawiera opis wybranych metod poznawczo-behawioralnych wykorzystywanych w pracy z wymagającą wsparcia młodzieżą z zaburzeniami ze spektrum autyzmu (ASD L1). We wstępie opisano pokrótce historię zaburzenia i podstawowe problemy występujące u dzieci i młodzieży ze spektrum zaburzeń autystycznych. W dalszej części przytoczono informacje na temat technik poznawczo-behawioralnych często stosowanych w pracy z tymi adolescentami. Omówiono przykładowe programy treningów umiejętności społecznych: PEERS (Program for the Education and Enrichment of Relationship Skills) oraz MASSI (Multimodal Anxiety and Social Skills Intervention). Przybliżono dwa programy wykorzystywane w pracy nad rozwijaniem…
Communicative skills in Spanish children with Autism Spectrum Disorder and children with Attention Deficit Hyperactivity Disorder. Analysis through p…
2018
Background Communicative skills are one of the main deficits experienced by children with Autism Spectrum Disorder (ASD). The differential diagnosis is a complex issue that clinicians often face. For this reason, this study has two objectives: 1) to analyze the similarities and differences that children with Attention Deficit Hyperactivity Disorder (ADHD) and children with ASD present in their linguistic and communicative skills, through parentś perceptions and narrative production; 2) to identify the relative importance of the skills analyzed in discriminating children with ASD versus children with ADHD, as well as the classification power of each of the two measurement methods used. Metho…
Narratives of children with high-functioning autism spectrum disorder: A meta-analysis
2016
Abstract Background The aim of this meta-analysis was to analyze the narrative performance of children and adolescents with high-functioning Autism Spectrum Disorders (ASD) in terms of microstructure, macrostructure and internal state language. Method A systematic literature search yielded 24 studies that met the predetermined inclusion criteria. Effect sizes for each study were calculated for eight variables and analyzed using a random effects model. Intellectual ability, age and type of narrative were considered as potential moderators. Results Results revealed that the children with ASD performed significantly worse than their peers on all the variables considered. Conclusions Findings a…
Cranio-Facial Characteristics in Children with Autism Spectrum Disorders (ASD)
2019
Background: Cranio-facial anomalies frequently occur in neurodevelopmental disorders because both face and brain are derived from neuroectoderm. The identification of differences in the facial phenotype of children with Autism Spectrum Disorders (ASD) may reflect alterations in embryologic brain development in children with ASD. Methods: we evaluated 33 caucasian children with ASD using a 2D computerized photogrammetry. Anthropometric euclidean measurements and landmarks located on the soft tissue of the face and head, were based on five cranio-facial indexes. Relationships between anthropometric z-scores and participant characteristics (i.e., age, Global IQ, severity of autistic symptoms m…