Search results for "speech"
showing 10 items of 1281 documents
Variable phenotype in 17q12 microdeletions: Clinical and molecular characterization of a new case
2014
Microdeletions of 17q12 including the hepatocyte nuclear factor 1 beta (HNF1B) gene, as well as point mutations of this gene, are associated with the Renal Cysts and Diabetes syndrome (RCAD, OMIM 137920) and genitourinary alterations. Also, microdeletions encompassing HNF1B were identified as a cause of Mayer-Rokitansky-Kuster-Hauser Syndrome (MRKH, OMIM 277000) in females and, recently, were associated with intellectual disability, autistic features, cerebral anomaly and facial dysmorphisms. In this report, we describe a boy with a deletion in 17q12 region detected by SNP array, encompassing the HNF1B gene, that showed dysmorphic features, intellectual disability (ID), serious speech delay…
Numerical simulation of glottal flow
2012
In cases of permanent immobility of both vocal folds patients have difficulties with breathing but rarely with voicing. However, clinical experience shows that the shape of the larynx (voice box) seems to have a significant influence on the degree of airflow and breathing pattern. In order to find an optimal geometry of the larynx in terms of easiness for breathing after the surgical change of vocal folds or false vocal cords (ventricular folds), a set of numerical simulations of glottal flow for weakly compressible Navier-Stokes equations has been performed. We compare airflow resistance and volumetric flow rate for several geometry concepts for inspiration as well as expiration. Finally, …
External laryngeal frame function in voice production revisited: A review
1996
Research indicates significant contribution of extrinsic laryngeal mechanisms to voice production. This article reviews the major theories of the role of the external laryngeal factors in voice production and relevant experimental data. The review suggests that partly neglected external factors and possibly even misinterpretation of some of the recently documented individual variation in physiological data may have unnecessarily complicated the issues pertaining to the interplay between the physiological mechanisms of the larynx. The implications of contemporary findings and documentation in the modeling of the extrinsic factors are discussed and a synthesis of empirical data into two simpl…
ERP correlates of letter identity and letter position are modulated by lexical frequency
2013
The encoding of letter position is a key aspect in all recently proposed models of visual-word recognition. We analyzed the impact of lexical frequency on letter position assignment by examining the temporal dynamics of lexical activation induced by pseudowords extracted from words of different frequencies. For each word (e.g., BRIDGE), we created two pseudowords: A transposed-letter (TL: BRIGDE) and a replaced-letter pseudoword (RL: BRITGE). ERPs were recorded while participants read words and pseudowords in two tasks: Semantic categorization (Experiment 1) and lexical decision (Experiment 2). For high-frequency stimuli, similar ERPs were obtained for words and TL-pseudowords, but the N400…
The role of linguistic and cognitive factors in emotion recognition difficulties in children with ASD, ADHD or DLD.
2018
Background Many children with neurodevelopmental disorders such as autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD) or developmental language disorder (DLD) have difficulty recognizing and understanding emotions. However, the reasons for these difficulties are currently not well understood. Aims To compare the emotion recognition skills of children with neurodevelopmental disorders as well as those children's skills with the skills of their typically developing (TD) age peers. Also, to identify the role of underlying factors in predicting emotion recognition skills. Methods & procedures The 6-10-year-old children (n = 50) who participated in the study had eith…
Developmental trajectories of early communication skills.
2012
Purpose This study focused on developmental trajectories of prelinguistic communication skills and their connections to later parent-reported language difficulties. Method The participants represent a subset of a community-based sample of 508 children. Data include parent reports of prelinguistic communication skills at 12, 15, 18, and 21 months and language difficulties at age 4;7 (years;months). The authors used latent profile analysis to identify groups of children with differing developmental trajectories of prelinguistic communication skills ( n = 271). The relations among these groups and follow-up data of parent-reported concerns of language development ( n = 187), as well as the ro…
Continuity From Prelinguistic Communication to Later Language Ability: A Follow-Up Study From Infancy to Early School Age.
2016
Purpose This longitudinal study examined the development of prelinguistic skills and the continuity of communication and language from the prelinguistic stage to school age. Method Prelinguistic communication of 427 Finnish children was followed repeatedly from 6 to 18 months of age ( n = 203–322 at ages 6, 9, 12, 15, and 18 months), and its associations with language ability at ages 2;0 ( n = 104), 3;0 ( n = 112), 4;7 ( n = 253), 5;3 ( n = 102), and 7;9 ( n = 236) were examined using latent growth curve modeling. Results Prelinguistic development across several skills emerged as a rather stable intraindividual characteristic during the first 2 years of life. Continuity from prelinguistic …
Basic numeracy in children with specific language impairment: heterogeneity and connections to language.
2006
Purpose This study examined basic numerical skills in children with specific language impairment (SLI) and how well linguistic factors explain the variance in these children’s number skills. Method The performance of children with SLI ( n = 29) was compared with that of typically developing children along a continuum ranging from preschool to 3rd grade ( n = 20, 47, 40, and 33). This facilitated both linguistic and educational age comparisons. To study number skills within the SLI group more closely, this group was divided into subgroups on the basis of their performance in verbal and nonverbal numerical skills. The performance of the different SLI subgroups on the linguistic and nonverbal…
Children with differing developmental trajectories of prelinguistic communication skills: language and working memory at age 5.
2014
Purpose In this article, the authors examine the developmental continuity from prelinguistic communication to kindergarten age in language and working memory capacity. Method Following work outlining 6 groups of children with different trajectories of early communication development (ECD; Määttä, Laakso, Tolvanen, Ahonen, & Aro, 2012), the authors examined their later development by psychometric assessment. Ninety-one children first assessed at ages 12–21 months completed a battery of language and working memory tests at age 5;3 (years;months). Results Two of the ECD groups previously identified as being at risk for language difficulties continued to show weaker performance at follow-u…
Prepositions and pronouns in connected discourse of individuals with aphasia
2018
The lexical-grammatical divide has been a widely addressed topic in aphasia. Speech parts are generally classified as either belonging to a lexical or a grammatical category based on the frequency of acquisition of new members in their paradigms (open vs. closed classes), thus neglecting heterogeneity within categories. Such an approach has led to contradictory findings. First, prepositions form closed classes, but are classically taken as lexical items. Pronouns, also belonging to a closed class, are analyzed as grammatical elements. Second, both within the group of prepositions and pronouns, forms with different syntactic and semantic properties co-exist. Following the theoretical notions…