Search results for "spiromesifen"

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Topical bioassay of Oberon® on Drosophila melanogaster pupae: delayed effects on ovarian proteins, cuticular hydrocarbons and sexual behaviour

2021

International audience; Spiromesifen (Oberon? 240 SC; concentrated solution; Bayer CropScience, Germany) a pesticide derived from spirocyclic tetronic acids, acts mainly though blocking lipid biosynthesis via acetyl-CoA carboxylase. However, its mode of action requires further analyses. This study aims to evaluate the sublethal effects of spiromesifen on the fruit fly Drosophila melanogaster. The treatment was carried out by topical application on newly moulted pupae using two concentrations (LD10 = 21.45 and LD25 = 39.53 ?g a.i./pupa). Our results showed that the developmental duration of larvae and pupae were not significantly affected by treatment. However, spiromesifen caused delayed ef…

0106 biological sciencesanimal structuresprogeny010603 evolutionary biology01 natural sciencesOberonLipid biosynthesisBioassaycomputer.programming_languagebiology010604 marine biology & hydrobiologycuticular hydrocarbonsfungisexual behaviour[SDV.BDLR]Life Sciences [q-bio]/Reproductive BiologyPesticidebiology.organism_classificationspiromesifenproteinsPupaBiochemistryAnimal Science and ZoologyhexapodaDrosophila melanogasterdelayed effectscomputerDevelopmental Biology
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Pre-imaginal exposure to Oberon® disrupts fatty acid composition, cuticular hydrocarbon profile and sexual behavior in Drosophila melanogaster adults

2021

International audience; Oberon® is a commercial formulation of spiromesifen, a pesticide inhibitor of lipid biosynthesis via acetyl CoA carboxylase, widely used in agricultural crop protection. However, its mode of action requires further analysis. We currently examined the effect of this product on Drosophila melanogaster as a non-target and model organism. Different concentrations of spiromesifen were administered by ingestion (and contact) during pre-imaginal development, and we evaluated its delayed action on adults. Our results suggest that spiromesifen induced insecticidal activity on D. melanogaster. Moreover, spiromesifen treatment significantly increased the duration of larval and …

Male0106 biological sciencesInsecticidesmedicine.medical_specialtyPhysiologyHealth Toxicology and MutagenesisAnimal ScalesBiologyToxicology01 natural sciencesBiochemistrySexual Behavior Animal03 medical and health sciencessexual behaviorInternal medicineLipid biosynthesisMelanogastermedicineAnimalsSpiro CompoundsMode of action030304 developmental biology0303 health sciencesLarvacuticular hydrocarbonsFatty AcidsfungiAcetyl-CoA carboxylasetoxicityLipid metabolismCell BiologyGeneral Medicinebiology.organism_classificationspiromesifenHydrocarbons[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology010602 entomologyDrosophila melanogasterEndocrinologyToxicityFemaleDrosophila melanogasterComparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
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