Search results for "spirometria"
showing 8 items of 8 documents
VHb-siirtogeenin vaikutukset geenimuunnellun nieriän (Salvelinus alpinus) hapenkulutukseen ja kasvuun
2012
Nieriä (Salvelinus alpinus) on arvostettu laji sekä urheilukalastuksessa että ruokakalana. Vähentyneiden populaatioiden ja viljelyssä havaittujen ongelmien takia sitä ei kuitenkaan Suomessa voida taloudellisesti hyödyntää parhaalla mahdollisella tavalla. Ilmastonmuutos voi hankaloittaa ennestään nieriän viljelyä, sillä se on kylmän veden laji. Tulevaisuudessa voi siirtogeenisten lajien käyttö ruokakalana olla mahdollista niiden uusien ominaisuuksien ja tehokkaamman viljelyn takia. Tässä tutkimuksessa selvitettiin miten bakteerihemoglobiinia (VHb) koodaava VHb-siirtogeeni vaikuttaa nieriän hapenkulutukseen ja kasvuun. Geenin vaikutuksia tutkittiin mittaamalla kalojen hapenkulutusta kolmessa …
Telomere Length in Circulating Leukocytes is Associated with Lung Function and Disease
2014
Several clinical studies suggest the involvement of premature ageing processes in chronic obstructive pulmonary disease (COPD). Using an epidemiological approach, we studied whether accelerated ageing indicated by telomere length, a marker of biological age, is associated with COPD and asthma, and whether intrinsic age-related processes contribute to the interindividual variability of lung function. Our meta-analysis of 14 studies included 934 COPD cases with 15 846 controls defined according to the Global Lungs Initiative (GLI) criteria (or 1189 COPD cases according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria), 2834 asthma cases with 28 195 controls, and s…
Criteri spirometrici per la diagnosi di bronco-ostruzione in soggetti anziani
2008
Dynaamiset keuhkotoiminnat kilpauimareilla maalla ja vedessä sekä maksimaalisen uintikuormituksen yhteydessä
2002
Marja Päivinen Dynaamiset keuhkotoiminnat kilpauimareilla maalla ja vedessä maksimaalisen uintikuormituksen yhteydessä. Liikuntajj;siologian pro gradu-tutkielma. Liikuntabiologian laitos. Jyväskylän Yliopisto. Hengitys on tärkeä osa kestävyysurheilusuoritusta. Uinnin hengitys eroaa maalla tehtävien lajien hengityksestä monin tavoin. Sisäänhengitys ja uloshengitys tapahtuvat käsivetorytmin mukaan, uloshengitys tapahtuu veden aiheuttamaa vastusta vastaan ja kehonasento on vaakatasossa. Lisäksi ympäröivä vesi puristaa elimistöä ja johtaa lämpöä tehokkaasti vaikuttaen uinnin aikaiseen hengitykseen. Tässä tutkimuksessa selvitettiin pitkän uintiharjoitustaustan omaavien ja kokeneiden kilpauimarei…
Genetic and Environmental Effects on Telomere Length and Lung Function : A Twin Study
2017
Background The purpose of the study was to estimate the heritability of leukocyte telomere length (LTL) and lung function and to examine whether LTL and lung function share genetic or environmental effects in common. Methods 386 monozygotic and dizygotic Finnish twin sisters (age 68.4±3.4 years) were included. Relative LTL was determined from peripheral blood DNA by qPCR. Lung function measures of FEV1, FVC, FEV1/FVC, and PEF were derived from spirometry. Genetic modeling was performed with MPlus statistical software. Results Univariate analysis revealed that in LTL, 62% (95% confidence interval 50–72) of the variance was explained by additive genetic and 38% (28–50) by unique environmental…
Associations between muscle strength, spirometric pulmonary function and mobility in healthy older adults
2014
Background: Pathological obstruction in lungs leads to severe decreases in muscle strength and mobility in patients suffering from chronic obstructive pulmonary disease. The purpose of this study was to investigate the interdependency between muscle strength, spirometric pulmonary functions and mobility outcomes in healthy older men and women, where skeletal muscle and pulmonary function decline without interference of overt disease. Methods: 135 69 to 81‐yr‐old participants were recruited into the cross‐sectional study, which was performed as a part of European study MyoAge. Full, partial and no mediation models were constructed to assess the interdependency between muscle strength (handgr…
La spirometria nel bambino collaborante
2016
La spirometria fornisce al medico l’opportunità di accertare la normalità ed il grado di anomalia della funzione respiratoria. Oggi è disponibile una grande varietà di attrezzature computerizzate per l’esecuzione della spirometria in età pediatrica e, in particolare, gli apparecchi che si basano sulla misura del flusso mediante pneumotacografo o turbina sono di facile uso ambulatoriale. I principali parametri misurati sono: FVC, FEV1, PEF, FEF25-75 ed il rapporto FEV1/FVC %. Attraverso l’esame spirometrico è possibile identificare almeno 3 pattern di condizione respiratoria patologica: 1) la disfunzione ventilatoria di tipo ostruttivo; 2) la disfunzione ventilatoria di tipo restrittivo; 3) …
Near-normal aerobic capacity in long-term survivors after lung transplantation
2021
The clinical course of lung transplantation (LT) is diverse: some patients present chronic lung allograft dysfunction (CLAD) and progressive decline in pulmonary function, but others maintain normal spirometric values and active lives. Objectives The aim of this study was to elucidate whether long-term LT survivors with normal spirometry achieve normal exercise capacity, and to identify predictive factors of exercise capacity. Methods This was a cross-sectional multicentre study, where bilateral LT recipients who survived at least 10 years after LT, with normal spirometry, no diagnosis of CLAD and modified Medical Research Council dyspnoea degree ≤2 underwent cardiopulmonary exercise testin…