Search results for "spirooxindole"

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Synthesis and Structure Elucidation of Novel Spirooxindole Linked to Ferrocene and Triazole Systems via [3 + 2] Cycloaddition Reaction

2022

In the present work, a novel heterocyclic hybrid of a spirooxindole system was synthesized via the attachment of ferrocene and triazole motifs into an azomethine ylide by [3 + 2] cycloaddition reaction protocol. The X-ray structure of the heterocyclic hybrid (1″R,2″S,3R)-2″-(1-(3-chloro-4-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carbonyl)-5-methyl-1″-(ferrocin-2-yl)-1″,2″,5″,6″,7″,7a″-hexahydrospiro[indoline-3,3″-pyrrolizin]-2-one revealed very well the expected structure, by using different analytical tools (FTIR and NMR spectroscopy). It crystallized in the triclinic-crystal system and the P-1-space group. The unit cell p…

spirooxindole; ferrocene; triazole; azomethine ylide; [3 + 2] cycloaddition (32CA) reactiontriazoleazomethine ylideChemistry (miscellaneous)Organic ChemistryDrug DiscoveryferroceneMolecular MedicinePharmaceutical Sciencespirooxindole[3 + 2] cycloaddition (32CA) reactionPhysical and Theoretical ChemistryAnalytical ChemistryMolecules; Volume 27; Issue 13; Pages: 4095
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