Search results for "squalene"

showing 4 items of 24 documents

Solid nanoemulsion as antigen and immunopotentiator carrier for transcutaneous immunization

2015

Imiquimod, a toll-like receptor 7 (TLR7) agonist, is an active pharmaceutical ingredient (API) established for the topical treatment of several dermal cancerous and precancerous skin lesions. Within this work, the immunostimulatory effect of imiquimod is further exploited in a transcutaneous immunization (TCI) approach based on a solid nanoemulsion (SN) formulation. SN contains a combination of imiquimod with the model peptide antigen SIINFEKL as a novel approach to omit needle and syringe and optimize dermal antigen administration. Excipients including sucrose fatty acid esters and the pharmaceutically acceptable oils MCT (middle chain triglycerides), avocado oil, jojoba wax and squalene a…

0301 basic medicineSkin NeoplasmsChemistry PharmaceuticalImmunologyAntineoplastic AgentsImiquimodImmunopotentiatorBiologyAdministration Cutaneous030226 pharmacology & pharmacyMice03 medical and health sciencesFreeze-dryingSqualenechemistry.chemical_compoundDrug Delivery Systems0302 clinical medicineAdjuvants ImmunologicAntigenIn vivomedicineAnimalsHumansActive ingredientImiquimodChromatographyVaccinationPermeationNanostructuresMice Inbred C57BL030104 developmental biologychemistryLangerhans CellsImmunologyAminoquinolinesImmunizationOilsPrecancerous Conditionsmedicine.drugCellular Immunology
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Metallic Core Nanocarriers for Multiple Cancer Targeting

2014

SPIOns Inulin Squalene Magnetic targeting
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Emerging opportunities for the effective valorization of wastes and by-products generated during olive oil production process: Non-conventional metho…

2015

Abstract Background A large amount of wastes and by-products are generated during olive oil production process. Traditionally, these products have been considered as a problem. However, they constitute a great source of high-added value compounds, which have the potential to be used as food additives and/or nutraceuticals. Therefore, valorization of wastes and by-products from food industry kills two birds with one stone and addresses both the use of waste and by-products and societal health, thus greatly contributing for a sustainable food chain from an environmental and economical point of view. Scope and approach In the present review, current and new insights in the recovery of high-add…

[SDV.BIO]Life Sciences [q-bio]/Biotechnologyfood.ingredientFood industry[SDV]Life Sciences [q-bio]By-products01 natural sciences12. Responsible consumptionUltrasoundsSqualenechemistry.chemical_compound0404 agricultural biotechnologyNutraceuticalfoodAdded value[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringMicrowaves2. Zero hungerOlive wastesWaste managementbusiness.industryFood additive010401 analytical chemistryExtraction (chemistry)04 agricultural and veterinary sciencesSub- and supercritical fluid extraction040401 food scienceSupercritical fluid0104 chemical sciencesElectrotechnologieschemistry13. Climate actionEnvironmental sciencebusiness[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood ScienceBiotechnologyOlive oilTrends in Food Science & Technology
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Isolierung und Identifizierung von Sterinen im Metabolismus des Pilzes Botrytis cinerea / Isolation and identification of sterols in the metabolism o…

1983

The fungus Botrytis cinerea, which belongs to the class of ascomycetes, has been analysed for its sterol composition. It is able to produce ergosterol, cerevisterol, lanosterol/dihydrolanosterol and cholesterol besides β-sitosterol. The identification of the sterols is carried out with different analytical methods including mass spectrometry. In the extracts of the mycelium also squalene has been identified

ErgosterolErgosterol peroxidebiologyChemistryLanosterolfungiFungusbiology.organism_classificationGeneral Biochemistry Genetics and Molecular BiologySterolchemistry.chemical_compoundSqualeneBiochemistrypolycyclic compoundslipids (amino acids peptides and proteins)MyceliumBotrytis cinereaZeitschrift für Naturforschung C
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