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showing 10 items of 1317 documents

Dietary polyunsaturated fatty acids may increase plasma LDL-cholesterol and plasma cholesterol concentrations in carriers of an ABCG1 gene single nuc…

2011

Abstract Background ABCG1 mediates cellular cholesterol transport, but there is very little known about the influence of ABCG1 polymorphisms on human plasma lipoprotein cholesterol concentrations or on the interactions of these polymorphisms with diet. Objective Our objective was to investigate whether interactions between PUFA intake and ABCG1 polymorphisms modulate associations with plasma total cholesterol (TC), LDL- and HDL-cholesterol in two Spanish populations. Methods We grounded our investigation on two general population-based studies: the Hortega study (population A) and the Pizarra study (population B). Participants included 1178 individuals (50.0% women, age range 21–85 years) a…

AdultMaleHeterozygotemedicine.medical_specialtyPopulationSingle-nucleotide polymorphismBiologyPolymorphism Single NucleotideYoung Adultchemistry.chemical_compoundGene FrequencySurveys and QuestionnairesInternal medicineGenotypemedicineHumansGene–environment interactionAlleleeducationAllele frequencyATP Binding Cassette Transporter Subfamily G Member 1AgedAged 80 and overchemistry.chemical_classificationGeneticseducation.field_of_studyChi-Square DistributionCholesterolHomozygoteCholesterol LDLMiddle AgedDietUp-RegulationCholesterolPhenotypeEndocrinologychemistrySpainFatty Acids UnsaturatedATP-Binding Cassette TransportersFemaleGene-Environment Interactionlipids (amino acids peptides and proteins)Cardiology and Cardiovascular MedicinePolyunsaturated fatty acidAtherosclerosis
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Differential association of polymorphisms in the TNFalpha region with psoriatic arthritis but not psoriasis.

2002

To investigate the potential association of tumour necrosis factor alpha (TNFalpha) microsatellite and promoter alleles with psoriatic arthritis (PsA).DNA from 89 white patients with PsA, 65 patients with psoriasis, and 99 healthy white controls was investigated for two TNFalpha promoter (-238 and -308) and three microsatellite polymorphisms (TNFa, c, and d). Patients had previously been studied by serology for HLA class I antigens and by sequence-specific polymerase chain reaction for DRB1* alleles. In addition, TNFalpha production of Ficoll separated peripheral blood mononuclear cells (PBMC) into culture supernatants after stimulation with lipopolysaccharide, alphaCD3 antibodies, phytohae…

AdultMaleImmunologyArthritisEnzyme-Linked Immunosorbent AssayHuman leukocyte antigenurologic and male genital diseasesPeripheral blood mononuclear cellPolymerase Chain ReactionGeneral Biochemistry Genetics and Molecular BiologyStatistics NonparametricPsoriatic arthritisRheumatologyPsoriasismedicineOdds RatioImmunology and AllergyHumansPsoriasisPromoter Regions GeneticAllelesCells CulturedPhytohaemagglutininAgedAged 80 and overChi-Square DistributionPolymorphism Geneticbiologybusiness.industryTumor Necrosis Factor-alphaHaplotypeArthritis PsoriaticMiddle Agedmedicine.diseaseExtended ReportCase-Control StudiesImmunologybiology.proteinLeukocytes MononuclearFemaleAntibodybusinessMicrosatellite RepeatsAnnals of the rheumatic diseases
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[A gastric polypoid signet ring cell carcinoma]

2007

The authors signal a case of gastric polypoid signet ring cell carcinoma, of particular interest for its rarity like show from the review of the literature, which is the first to have been described after Tabaru's citation.The study has been carried out at the Department of Surgical and Oncological Sciences of the University of Palermo. It has been based on 2000 cases analysed from June 2001 to December 2003.The authors advance some and emphasizes the diagnostic flow chart and therapeutic choices adopted.We agree that the endoscopic polypectomy is surgical procedure of first approach, but modifying the therapeutic guideline in relation to histologic examination, like happened in the case in…

AdultMaleLinee guida pratiche come argomentoBiopsyFemminaSex FactorSettore MED/08 - Anatomia PatologicaDi mezza etàDistribuzione Chi-SquarePolypsSex FactorsPolypPrevalenzaFattori sessualiStomach NeoplasmsPrevalenceHumansAge FactorAgedAged 80 and overChi-Square DistributionInvecchiato 80 e oltreAdultoAge FactorsEndoscopyMiddle AgedImmunohistochemistryI polipiCarcinoma cellula ad anello con sigilloBiopsiaSettore MED/18 - Chirurgia GeneraleNeoplasie Di StomacoPractice Guidelines as TopicGli esseri umaniFemaleFattori di etàEndoscopiaMaschioimmunoistochimicaCarcinoma Signet Ring CellHumanInvecchiato
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In-Vivo Estimation and Repeatability of Force-Length Relationship and Stiffness of the Human Achilles Tendon using Phase Contrast MRI

2008

Purpose To devise a method using velocity encoded phase contrast MRI and MR-compatible dynamometry, for in vivo estimation of elastic properties of the human Achilles tendon and to assess within-session and day-to-day repeatability of this technique. Materials and Methods Achilles tendon force and calcaneus-movement-adjusted displacement were measured during a submaximal isometric plantarflexion in 4 healthy subjects, four repeated trials each. The measured force-length (F-L) relationship was least-squares fitted to a cubic polynomial. Typical error was calculated for tendon displacement at multiple force levels, stiffness from the “linear region,” and transition point from the displacement…

AdultMaleMaterials scienceIsometric exerciseAchilles TendonArticleTransition pointmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingDisplacement (orthopedic surgery)Least-Squares AnalysisAchilles tendonStiffnessReproducibility of ResultsAnatomyRepeatabilitymusculoskeletal systemMagnetic Resonance ImagingTendonmedicine.anatomical_structureCalcaneusStress Mechanicalmedicine.symptomBiomedical engineering
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Neomuscular fatigue to power loading using a weight-stack device fitted with or without additional rubber band resistance

2014

The addition of a rubber band (RB) to traditional weight-based resistance may be beneficial regarding the deceleration phase common during explosive power actions with light weights. This would lead to greater force and muscle activity during the latter part of the movement, but this may influence the distribution of neuromuscular fatigue. Fifteen men performed 2 knee extension power loadings (5 × 5 × 40% of 1 repetition maximum [1RM]) using a typical weight-stack device without (WS) and with the addition of a RB (WS + RB) in a crossover design. Concentric contractions were performed as fast as possible, and analyzed for torque, velocity, power, and vastus lateralis and medialis surface ele…

AdultMaleMaterials scienceKnee JointPhysical Therapy Sports Therapy and RehabilitationIsometric exerciseElectromyographyConcentricQuadriceps MuscleRoot mean squareYoung AdultIsometric ContractionmedicineHumansOrthopedics and Sports MedicineLactic AcidMuscle StrengthLead (electronics)ta315Cross-Over StudiesMuscle fatiguemedicine.diagnostic_testElectromyographyResistance TrainingGeneral MedicineAmplitudeTorqueMuscle FatigueExercise TestRange of motionBiomedical engineeringThe Journal of Strength and Conditioning Research
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EMG, heart rate, and accelerometer as estimators of energy expenditure in locomotion.

2014

AB Purpose: Precise measures of energy expenditure (EE) during everyday activities are needed. This study assessed the validity of novel shorts measuring EMG and compared this method with HR and accelerometry (ACC) when estimating EE. Methods: Fifty-four volunteers (39.4 +/- 13.9 yr) performed a maximal treadmill test (3-min loads) including walking with different speeds uphill, downhill, and on level ground and one running load. The data were categorized into all, low, and level loads. EE was measured by indirect calorimetry, whereas HR, ACC, and EMG were measured continuously. EMG from quadriceps (Q) and hamstrings (H) was measured using shorts with textile electrodes. Validity of the met…

AdultMaleMean squared errorPopulationPhysical ExertionPhysical Therapy Sports Therapy and RehabilitationWalkingAccelerometerClothingQuadriceps MuscleRunningHeart RateLinear regressionStatisticsHeart rateAccelerometryHumansOrthopedics and Sports MedicineTreadmillta315educationElectrodesMathematicseducation.field_of_studyElectromyographyEstimatorta3141Middle AgedExercise TestFemaleAkaike information criterionEnergy MetabolismMedicine and science in sports and exercise
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Effect of innervation zones in estimating biceps brachii force-EMG relationship during isometric contraction

2012

Measuring muscle forces in vivo is invasive and consequently indirect methods e.g., electromyography (EMG) are used in estimating muscular force production. The aim of the present paper was to examine what kind of effect the disruption of the physiological signal caused by the innervation zone has in predicting the force/torque output from surface EMG. Twelve men (age 26 (SD ±3)years; height 179 (±6)cm; body mass 73 (±6)kg) volunteered as subjects. They were asked to perform maximal voluntary isometric contraction (MVC) in elbow flexion, and submaximal contractions at 10%, 20%, 30%, 40%, 50% and 75% of the recorded MVC. EMG was measured from biceps brachii muscle with an electrode grid of 5…

AdultMaleMean squared errorintervation zonePhysical Exertionta221BiophysicsNeuroscience (miscellaneous)Isometric exerciseElectromyographyBicepsElectrode GridSensitivity and SpecificityRoot mean squareIsometric ContractionElbow JointmedicineMuscular forceHumansMuscle StrengthMuscle Skeletalta315ta218MathematicsOrthodonticsvalidationta214medicine.diagnostic_testta114ElectromyographyReproducibility of ResultsmodelingAnatomybody regionsNeurology (clinical)Stress Mechanicalhigh-density EMGneuromuscularLeave one out methodAlgorithmsJOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY
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Dynamics and molecular evolution of HIV-1 strains in Sicily among antiretroviral naïve patients.

2012

Abstract HIV-1 subtype B is the most frequent strain in Sicily. To date, there is no available data about the genetic diversity of HIV-1 viral strains circulating in Sicily among antiretroviral (ARV) naive subjects and the role of immigration as potential determinant of evolutionary dynamics of HIV-1 molecular epidemiology. For this purpose, HIV-1 polymerase (pol) sequences obtained from 155 ARV naive individuals from 2004 to 2009 were phylogenetically analysed. The overall rate of HIV-1 non-B infections was 31.0% (n = 48/155), increasing from 7.8% in 2004–2006 to 40.9% in 2009, and about one-third were identified as unique recombinant forms. CRF02_AG was the prevalent non-B clade (n = 28/4…

AdultMaleMicrobiology (medical)AdolescentPopulationHIV Infectionsnon-B subtypeBiologySettore MED/42 - Igiene Generale E ApplicataMicrobiologyCohort StudiesEvolution MolecularMolecular evolutionGeneticsCluster AnalysisHumansHIV-1 subtypes; non-B subtypes; CRF; Molecular evolution; HAART-naïve patientsChildEvolutionary dynamicseducationCladeSicilyMolecular BiologyPhylogenyEcology Evolution Behavior and SystematicsAgedMolecular Epidemiologyeducation.field_of_studyGenetic diversityHIV-1 subtypeChi-Square DistributionMolecular epidemiologyPhylogenetic treeHAART-naïve patientsStrain (biology)Infantvirus diseasesCRFMiddle AgedGenes polVirologyInfectious DiseasesChild PreschoolHIV-1Molecular evolutionFemale
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Transthoracic three-dimensional echocardiographic volumetry of distorted left ventricles using rotational scanning

1997

The purpose of this study was to evaluate the relation of transthoracic three- and two-dimensional echocardiographic left ventricular volumetry to cineventriculographic volumetry. Twenty-five patients with distorted left ventricles were included in the study. To demonstrate the impact of acquiring data by rotational scanning, we performed three- and two-dimensional echocardiography in 36 latex ventricles with data acquisition in different areas of the ultrasound sectors. Interobserver and intraobserver variability were calculated to test for reproducibility. The three-dimensional imaging system consisted of a rotation motor device, a transthoracic 2.5 MHz transducer, a conventional ultrasou…

AdultMaleModels Anatomicmedicine.medical_specialtyCardiac VolumeHeart VentriclesCardiac VolumeLeft VentriclesConventional ultrasoundRoot mean squareImage Processing Computer-AssistedHumansMedicineRadiology Nuclear Medicine and imagingAgedObserver VariationReproducibilitybusiness.industryUltrasoundReproducibility of ResultsMiddle AgedTransducermedicine.anatomical_structureVentricleRegression AnalysisFemaleRadiologyCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealJournal of the American Society of Echocardiography
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Randomized study comparing two tongue base surgeries for moderate to severe obstructive sleep apnea syndrome

2009

To compare the effectiveness and morbidity of the tongue base radiofrequency and tongue base suspension techniques combined with uvulopalatopharyngoplasty for moderate to severe obstructive sleep apnea.Prospective and randomized surgical trial at a university hospital.In total, 57 patients received either tongue base radiofrequency reduction (n = 29) or tongue base suspension (n = 28). Apnea-hypopnea index, lowest oxygen saturation (polysomnography), Epworth score, and side effects were assessed. Success was defined as aor =50 percent reduction and final apneahypopnea index15/h, and an Epworth score11.The success rates of the two procedures were 57.1 percent and 51.7 percent, respectively (…

AdultMaleModerate to severemedicine.medical_specialtyPolysomnographymedicine.medical_treatmentSeverity of Illness IndexTongue Baselaw.inventionTongueRandomized controlled triallawHumansMedicineProspective StudiesAgedSleep Apnea ObstructiveChi-Square Distributionbusiness.industryUvulopalatopharyngoplastyMiddle Agedmedicine.diseaseOtorhinolaryngologic Surgical ProceduresSurgeryObstructive sleep apneaLogistic ModelsTreatment OutcomeOtorhinolaryngologyCatheter AblationFemaleSurgerybusinessOtolaryngology–Head and Neck Surgery
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