Search results for "stance"
showing 10 items of 7708 documents
Rikoksista tuomitut naiset : yhteisöstä erottaminen ja takaisinliittymisen mahdollisuudet
2019
Tutkimus käsittelee yhteisöstä erottamisen ja siihen takaisinliittymisen mahdollisuuksia rikostaustaisten naisten elämässä. Tutkimuksen kohteena ovat rikostaustaisten naisten kertomukset elämänkulustaan. Tutkimuksessa analysoidaan naisten kertomuksia siirtymäriittiteorian eli yhteisöstä erottamisen, liminaalin ja takaisinliittämisen näkökulmasta. Aineisto on kerätty haastattelemalla 18 naista, jotka haastatteluhetkellä olivat joko suorittamassa vankeusrangaistustaan, ehdonalaisen vapauden valvonnassa tai rangaistuksensa suorittaneet. Aineiston analyysissa on käytetty narratiivista lähestymistapaa sekä Greimasin aktanttimallia. Aineiston analyysissa esiin nousevia keskeisiä teemoja ovat päih…
Nessuno resta indietro: un progetto di service learning
2022
La chiusura delle scuole ha provocato un incremento significativo della povertà educativa ha sollecitato l’opportunità di progettare interventi integrati di service learning per favorire il recupero e il potenziamento dei minori in difficoltà. 869 studenti del Corso di Laurea Magistrale in Scienze della Formazione Primaria dell’Università degli Studi di Palermo, sono stati coinvolti nella progettazione e nella realizzazione di percorsi didattici mirati, rivolti agli alunni “fragili” di 33 scuole palermitane. Complessivamente sono state erogate 60.000 ore in DAD di attività di recupero e di potenziamento dell’apprendimento di alunni della scuola primaria di Palermo. Le attività didattiche sf…
Il progetto Nessuno resta indietro: formazione alla ricerca didattica
2022
La chiusura delle scuole che ha provocato un incremento significativo della povertà educativa ha sollecitato l’opportunità di progettare interventi integrati di service learning per favorire il recupero e il potenziamento dei minori in difficoltà. 869 studenti del Corso di Laurea Magistrale in Scienze della Formazione Primaria dell’Università degli Studi di Palermo, sono stati coinvolti nella progettazione e nella realizzazione di percorsi didattici mirati, rivolti agli alunni “fragili” di 33 scuole palermitane. Complessivamente sono state erogate 60,000 ore in DAD di attività di recupero e di potenziamento dell’apprendimento di alunni della scuola primaria di Palermo. Le attività didattich…
Mucin 1 deficiency mediates corticosteroid insensitivity in asthma
2019
BACKGROUND: The loss of corticosteroid efficacy is an important issue in severe asthma management and may lead to poor asthma control and deterioration of airflow. Recent data indicate that Mucin 1 (MUC1) membrane mucin can mediate corticosteroid efficacy in chronic rhinosinusitis, but the role of MUC1 in uncontrolled severe asthma is unknown. The objective was to analyze the previously unexplored role of MUC1 on corticosteroid efficacy in asthma. METHODS: Mucin 1 expression was evaluated by real-time PCR in human bronchial epithelial cells (HBEC) and blood neutrophils from uncontrolled severe asthma (n=27), controlled mild asthma (n=16), and healthy subjects (n=13). IL-8, MMP9, and GM-CSF …
Velocity-based resistance training: do women need greater velocity loss to maximize adaptations?
2021
Abstract Purpose Men and women typically display different neuromuscular characteristics, force–velocity relationships, and differing strength deficit (upper vs. lower body). Thus, it is not clear how previous recommendations for training with velocity-loss resistance training based on data in men will apply to women. This study examined the inter-sex differences in neuromuscular adaptations using 20% and 40% velocity-loss protocols in back squat and bench press exercises. Methods The present study employed an 8-week intervention (2 × week) comparing 20% vs. 40% velocity-loss resistance training in the back squat and bench press exercises in young men and women (~ 26 years). Maximum strengt…
Effects of ectopic expression of NGAL on doxorubicin sensitivity.
2012
Neutrophil gelatinase-associated lipocalin (NGAL, a.k.a Lnc2) is a member of the lipocalin family which has diverse roles including stabilizing matrix metalloproteinase-9 from auto-degradation and as siderocalins which are important in the transport of iron. NGAL also has important biological functions involved in immunity and inflammation as well as responses to kidney damage. NGAL expression has also been associated with certain neoplasia and is important in the metastasis of breast cancer. Many advanced cancer patients have elevated levels of NGAL in their urine and it has been proposed that NGAL may be a prognostic indicator for certain cancers (e.g. breast, brain, and others). NGAL exp…
Nostalgia, community and resistance : Counter-cultural politics in a Finnish skinzine
2019
Culture and community building are an essential part of the appeal of the far-right and fascist movements. Studying their cultural products is therefore important for a deeper understanding of the movement and their modus operandi. One elemental part of their culture are the so-called zines, small-scale do-it-yourself magazines intended for scene members. In certain respects, the far-right zines, skinzines, follow the forms and trends of other underground publications, especially punk-zines, with which they also share the resistance identity as stigmatized and marginalized actors. However, the political visions in skinzines are more or less opposite to ‘democratic zines’, creating certain t…
A fluorescence study of the loading and time stability of doxorubicin in sodium cholate/PEO-PPO-PEO triblock copolymer mixed micelles
2019
Abstract Hypothesis Doxorubicin hydrochloride (DX) is one of the most powerful anticancer agents though its clinical use is impaired by severe undesired side effects. DX encapsulation in nanocarrier systems has been introduced as a mean to reduce its toxicity. Micelles of the nonionic triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) (PEO-PPO-PEO), are very promising carrier systems. The positive charge of DX confines the drug to the hydrophilic corona region of the micelles. The use of mixed micelles of PEO-PPO-PEO copolymers and a negatively charged bile salt should favour the solubilization of DX in the apolar core region of the micelles. Experiments We st…
Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL.
2022
Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing future cardiovascular events. Low-density lipoproteins (LDL) have been successfully targeted, and their reduction is one of the key preventing measures in patients with atherosclerotic disease. LDL particles are pivotal for the formation and progression of atherosclerotic plaques; yet, they are quite heterogeneous, and smaller, denser LDL species are the most atherogenic. These particles have greater arterial entry and retention, higher susceptibility to oxidation, as well a…
A firm's activity in social media and its relationship with corporate reputation and firm performance
2015
There is growing debate about whether companies’ investments in social media really pay off. This research attempts to contribute to this discussion by investigating the relationship between a firm’s social media activity and two outcomes, namely, company reputation and firm financial performance. Two propositions are developed based on theory and tested with a sample of 59 companies. The findings suggest that a firm’s social media activity is only partially linked with its financial performance and is not linked with corporate reputation. The implications of the research suggest that little is known about the relationships between a firm’s social media activity and corporate reputation and…